Genetic factors and disease/inheritance patterns Flashcards
1
Q
Genotype
A
genetic constitution of an individual
2
Q
Phenotype
A
clinical appearance (results from interaction of environment and genotype)
3
Q
Allele
A
one of several alternative forms of a gene at a specific locus
4
Q
Locus
A
position of gene/DNA on genetic map
5
Q
Polymorphism
A
frequent hereditary variations at a locus
6
Q
Homozygous
A
both alleles are the same at a locus
7
Q
Heterozygous
A
alleles are different at a locus
8
Q
Hemizygous
A
genes carried on an unpaired chromosome
refers to a locus on an x chromosome in males
9
Q
Autosomal dominant inheritance
A
only manifests in heterozygous state
affects males+females equally
affected individuals in multiple generations
transmission by individuals of both sexes to both sexes
