Genes & Central Dogma of Biology Flashcards

1
Q

Gene

A

basic unit of genetic information; a segment of DNA that determines a trait

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2
Q

Where are genes located?

A

on chromosomes

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3
Q

Allele

A

alternate form of a gene

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4
Q

Homozygous

A

copies of an allele are the same

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5
Q

Heterozygous

A

copies of an allele are different

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6
Q

Expressed allele

A

dominant

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7
Q

Unexpressed allele

A

recessive

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8
Q

Non-sex-related chromosomes

A

autosomes

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9
Q

Sex-related chromosomes

A

sex chromosomes

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10
Q

Sex chromosomes determine

A

sex-linked traits

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11
Q

Central Dogma

A

DNA –> RNA –> Protein

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12
Q

Process from DNA to Protein

A

DNA –> transcription –> RNA –> translation –> Amino acids –> Protein folding –> Protein

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13
Q

Transcription

A

the process of copying a gene’s DNA sequence to make an RNA molecule; first step in gene expression

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14
Q

Translation

A

mRNA is decoded and a protein is produced

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15
Q

Protein folding

A

a linear polypeptide folds into its characteristic and functioning 3-D structure

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16
Q

3 regions of a gene

A

(1) Promoter, (2) Transcribed region, (3) Termination site

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17
Q

Promoter

A

specifies where RNA Polymerase will begin transcription

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18
Q

Transcribed region

A

“RNA coding region”
-part that gets transcribed into RNA

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19
Q

Termination site

A

Region of DNA that tells the RNA polymerase when transcription should stop

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20
Q

Character

A

a recognizable feature controlled by genetics

21
Q

Trait

A

a version of a character

22
Q

Protein

A

large, complex molecule that does most of the work in cells; required for structure, function, and regulation of tissues and organs

23
Q

Polypeptide chain

A

single, unbranched chain of amino acid

24
Q

Proteins have different structural levels

A

Primary, Secondary, Tertiary, Quaternary

25
Primary structure
amino acid monomers join to form polypeptide chains
26
Secondary structure
polypeptide chains may form alpha helices or beta pleated sheets
27
Tertiary structure
polypeptides fold, creating specific shapes
28
Quaternary structure
two or more polypeptides assemble to form larger protein molecules
29
Enzymes
speed up (catalyze) biochemical reactions
30
Structural Proteins
provide physical stability and movement
31
Defensive Proteins
recognize and respond to nonself substances (ex: antibodies)
32
Signaling Proteins
Control physiological processes (ex: hormones)
33
Receptor Proteins
receive and respond to chemical signals
34
Membrane Transporters
regulate passage of substances across cellular membranes
35
Storage Proteins
store amino acids for later use
36
Transport Proteins
bind and carry substances within the organism
37
Gene Regulatory Proteins
determine the rate of expression of a gene
38
Motor Proteins
cause movement of structures in the cell
39
Gated Channel Protein
opens in response to a stimulus; transport protein that opens a "gate" to allow a molecule to pass through the membrane
40
What are proteins composed of?
amino acids
41
Hydrophobic
repels water
42
Hydrophilic
mixes with water
43
Amino Acid
a group of organic molecules consisting of a basic amino group, an acidic carboxyl group, and an organic R group (side chain)
44
How do amino acids bond together?
bond together covalently in a condensation reaction by peptide linkages (peptide bonds)
45
Hormones
endocrine signals that enter the blood and activate target cells; either bind to specific receptors on cell surfaces or diffuse through cell membrane to bind to internal receptors
46
What can pass through hydrophobic lipid bilayer
small, uncharged molecules
47
What cannot pass through lipid bilayer
large polar molecules
48
How does a protein form?
one or more polypeptide chains fold into specific 3-D shapes