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Gynecology > Generalities > Flashcards

Generalities Flashcards

1
Q

2 hormones that is secreted by the testes

A

Testosterone

Mullerian-inhibiting factor

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2
Q

What enzyme converts testosterone to dihydrotestosterone?

A

5-a-reductase

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3
Q

Absence of mullerian-inhibiting factor causes ____

A

Uterus
Cervix
Oviducts
Upper 1/3 of vagina

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4
Q

Wolfian duct regress in the absence of ____

A

testosterone

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5
Q

The presence of ___ chromosome is the single most determinant of sex

A

Y

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6
Q

Mesonephric duct

A

Wolfian duct

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7
Q

Paramesonephric duct

A

Mullerian duct

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8
Q

Hypothesis wherein one X chromosome present in females is inactivated

A

Lyon hypothesis

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9
Q

sex chromatin mass

A

barr body

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10
Q

Found in nucleus of neutrophils in females

A

Drumstick appendages

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11
Q

What is detected in hair root test?

A

Fluorescent body (Y body)

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12
Q

Gold standard for sex determination

A

Karyotyping

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13
Q

AOG where all embryos have bipotential gonads

A

4-6 wks AOG

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14
Q

Cells that secrete testosterone

A

Leydig cells

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15
Q

Cells that secrete antimullerian hormone

A

Sertoli cells

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16
Q

AOG when testes descends through inguinal ring

A

7-9 mos AOG

17
Q

Sertoli cells develop at ___ wks

18
Q

Leydig cells develop at ___

19
Q

2 control mechanisms in devt if phenotypic sex

A

Classic endocrine mechanism

Local paracrine mechanism

20
Q

What hormone is required in the diff of external genitalia?

21
Q

Genital tubercle develops in to ___ tissue

A

erectile
M: glans penis, corpus cavernosum
F: clitoris, vestibular bulb

22
Q

Genital swelling in M fuse to form ___

A

scrotum and prepuce

23
Q

Genital swelling in F do NOT fuse but develop into…

A

labia minora

24
Q

Urogenital sinus in M develops into…

A

urethra

cowper’s and prostate gland

25
Q

Urogenital sinus in F develops into…

A

urethra
lower 2/3 of vagina
Bartholin’s and Skene’s glands

26
Q

Genotype for Turner syndrome

27
Q

Short stature, ovarian dysgenesis, shield chest with widely spaced nipples, webbed neck, coarctation of the aorta

A

Turner syndrome

28
Q

Testicular atrophy, eunichoid body shape, tall long extremities, gynecomastia, female hair distribution

A

Klinefelter syndrome

29
Q

Genotype of Klinefelter syndrome

30
Q

2 barr bodies, menstrual irregularities and learning d/o’s

A

Superfemale (XXX)

31
Q

Type of hermaphroditism with functional gonads

A

True hermaphroditism

32
Q

Genetic males with female phenotype

A

Male pseudohermaphrodites

33
Q

Causes adrenal androgen overproduction in the fetus

A

Congenital adrenal hyperplasia/

21 hydroxylase deficiency

34
Q

Sex determination established by genetic inheritance

A

Chromosomal/ genetic sex

Gynecology (7 decks)

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