General Surgery (Lower GI) Flashcards
Describe the pathophysiology of Appendicitis
Usually caused by luminal obstruction (secondary to faecoliths/lymphoid hyperplasia/impacted stool/tumour)
What are Faecoliths?
Faecal Debris and Calcium Salts
Give three risk factors of Appendicitis
Family History
Ethnicity (Caucasians)
Environmental (Seasonal - Summer)
Give 4 clinical features of Appendicitis
Pain (initial dull periumbilical, then later sharp in RIF)
Vomiting
Nausea
Anorexia
What is McBurney’s Point?
2/3 from Umbilicus to ASIS
Focus of peritoneal pain in late appendicitis
State three features OE of a patient with Appendicitis
Tachycardic
Tachypnoeic
Pyrexial
State two exams which would be positive in an Appendicitis patient
Psoas Sign - RIF pain with right hip extension (retrocoecal appendix irritates psoas muscle)
Rovsing’s Sign - RIF pain when LIF is palpated
Give 5 differentials for Appendicitis
Ectopic Pregnancy Ovarian Cyst Rupture Ureteric Stones Diverticulitis IBS
How would you manage an Appendicitis patient?
Laproscopic Appendicectomy
Describe 3 complications of Appendicitis. How could we reduce the risk?
Perforation
Appendiceal Mass
Pelvic Abscess
Antibiotic Treatment
Describe the pathophsyiology of Colorectal Cancer
Occurs via progression
Normal Mucosa to Colonic Adenoma (Polyps)
Colonic Adenoma to Invasive Adenocarcinoma
Describe the two genetic mutations associated with Colorectal Cancer
APC (Adenomatous Polyposis Coli) - Normally a tumour supressor gene, associated with FAP
HNPCC - DNA mismatch repair gene, associated with Lynch Syndrome
Give four risk factors for Colorectal Cancer
Age
IBD
Family History
Low Fibre Diet
Describe 3 presentations of Right Sided Colorectal Cancer
Late Presentation
Abdo Pain
Occult Bleeding
Describe 3 presentations of Left Sided Colorectal Cancer
Rectal Bleeding
Tenesmus
Change in bowel habit
What is the marker of Colorectal Cancer?
CEA
Not used in diagnosis but used to monitor progression
Give three possible imaging techniques for Colorectal Cancer
Colonoscopy
CT Scan
MRI Rectum
Describe Duke’s Staging of Colorectal Cancer
A - Confined to muscularis mucosa
B - Trough muscularis mucosa
C - Regional Lymph Nodes
D - Distant Metastases
Surgery is the mainstay of treatment for Colorectal Cancer. What blood vessels would have to be dissected and reanastamosed in a RIGHT Hemicolectomy?
Ileocolic
Right Colic
Right Middle Colic
Surgery is the mainstay of treatment for Colorectal Cancer. What blood vessels would have to be dissected and reanastamosed in a LEFT Hemicolectomy?
IMV
Left Colic
Left branch of middle colic
Surgery is the mainstay of treatment for Colorectal Cancer. What blood vessels would have to be dissected and reanastamosed in a Sigmoidectomy?
Inferior Mesenteric Artery
Give an example of when an Anterior Resection is used
High rectal tumours
Give an example of when an AP Resection is used
Low Rectal Tumours
What is the Hartmann’s Procedure?
Used in emergency bowel surgery
Complete resection of rectosigmoid colon with formation of end colosomy and closure of rectal stump
Reversible