General Surgery - Anorectal Flashcards

1
Q

What are the sx of haemorrhoids?

A
  • Painless bright red rectal bleeding
  • Pruritus
  • Rectal fullness or an anal lump, and soiling
  • Severe anaemia
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2
Q

How are haemmorhoids investigated?

A
  • Abdo exam
  • PR exam (internal haemmorhoids are not palpable)
  • Proctoscopy
  • Sigmoidoscopy
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3
Q

How are haemmorhoids treated?

A
  1. Medical: (1st-degree.) ↑Fluid and fibre is key ± topical analgesics & stool softener (bulk forming). Topical steroids for short periods only.
  2. Non-operative: (2nd & 3rd degree, or 1st degree if medical therapy failed.)
    • Rubber band ligation. Banding produces an ulcer to anchor the mucosa (SE: bleeding, infection; pain)
    • Sclerosants: (1st- or 2nd-degree.) 2mL of 5% phenol in oil is injected into the pile above the dentate line, inducing fibrotic reaction. .
  3. Surgery:
    • Haemmorhoid artery ligaton
    • Excisional haemorrhoidectomy
    • Stapled haemorrhoidopexy
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4
Q

What is Pilonidal sinus disease?

A
  • Disease of the inter-gluteal region*, characterised by the formation of a sinus in the cleft of the buttocks
  • Commonly affects males aged 16-30 years
  • It is starting from a hair follicle in the intergluteal cleft becoming infected or inflamed
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5
Q

How does pilonidal sinus disease present?

A
  • Intermittent red, painful, and swollen mass in the sacrococcygeal region
  • Commonly discharge from the sinus
  • Pilonidal sinus opens up onto the skin, but does not communicate with the anal canal
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6
Q

How do you manage pilonoidal sinuses?

A
  • Conservative: shaving the affected region and plucking the sinus free of any hair. Abx
  • Surgical
    • Incision and drainage; chronic: removal of the pilonidal sinus tract.
    • Excising the tract and laying open the wound
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7
Q

What is a perianal fistula?

A

Abnormal connection between the anal canal and the perianal skin

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8
Q

What are some of the causes of peri anal fistula?

A
  • IBD – Crohn’s/ UC
  • Systemic diseases – Tuberculosis, diabetes, HIV
  • Trauma hx - to the anal region
  • Previous radiation therapy to the anal region
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9
Q

How would we predict the trajectory of fistula?

A

The Goodsall Rule

  • External opening posterior to the transverse anal line – fistula tract will follow a curved course to the posterior midline
  • External opening anterior to the transverse anal line – fistula tract will follow a straight radial course to the dentate line
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10
Q

What classification is used to divide anal fistula into four distinct types:

A

Park’s classification system​

  1. Inter-sphincteric fistula (most common)
  2. Trans-sphincteric fistula
  3. Supra-sphincteric fistula (least common)
  4. Extra-sphincteric fistula
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11
Q

How are fistula managed?

A

Surgical:

  • A fistulotomy: laying the tract open by cutting through skin and subcutaneous tissue, allowing it to heal by secondary intention
  • The placement of a seton: (suitable for high tract disease) though the fistula attempts to bring together and close the tract, passing out at opening of the perianal skin adjacent to the external opening
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12
Q

What causes anorectal abscesses?

A
  • Caused by plugging of the anal ducts, the ducts that drain the anal glands in the anal wall, helping to ease the passage of faecal matter through mucus secretion.
  • Blockage -> fluid stasis -> infection
  • Common causative organisms include E. coli, Bacteriodes spp., and Enterococcus spp..
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13
Q

How are anorectal abscesses managed?

A
  • Conservative: analgesia + abx
  • Surgical: surgical incision and drainage. These can then be left to heal via secondary intention
  • Proctoscopy post drainage to check for perianal fistula
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14
Q

What is an anal fissure?

A
  • Tear in the mucosal lining of the anal canal, most commonly due to trauma from defecation of hard stool.
  • It can be classified according to its duration:
    • Acute – present for <6 weeks
    • Chronic – present for >6 weeks
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15
Q

What are the symptoms of anal fissure?

A
  • Intense pain post-defecation, which can last several hours.
  • Pain can be far out of proportion to the size of the fissure
  • Other sx: may include bleeding (commonly bright red blood on wiping) or itching, both typically post-defecation.
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16
Q

How would you examine?

A
  • DRE - palpation
  • EUA - examination under anaesthetic
  • Proctoscopy
17
Q

How are anal fissures managed?

A
  • Conservative: reducing RFs, analgesia
    • Increasing fibre and fluid
    • Stool softening laxatives: (e.g. Movicol or Lactulose)
    • Topic anaesthetics: e.g. lidocaine
    • Hot baths can to relax the anal sphincter
  • Medical: GTN cream or diltiazem cream
  • Surgical therapy (for chronic fissures)
    • Botox injections
    • Lateral sphincterotomy
18
Q

What is a rectal prolapse?

A
  • Protrusion of mucosal or full-thickness layer of rectal tissue out of the anus.
  • There are two main types* of rectal prolapse:
    • Partial thickness – the rectal mucosa protrudes out of the anus
    • Full thickness – the rectal wall protrudes out the anus
19
Q

What are the clinical features of a rectal prolapse?

A
  • Rectal mucus discharge
  • Faecal incontinence
  • Per rectum bleeding
  • Visible ulceration
20
Q

What are the surgical management options?

A

Surgical

  • Perineal approach
    • Delormes operation: the prolapsed lining of the rectal mucosa is removed and the underlying muscle reinforced with plicated sutures
    • Altemeier’s operation: resection of the redundant prolapsed bowel to restore the original anatomy
  • Abdominal approach: laparoscopically (most common), robotically, open
21
Q

What are the majority of anal cancers?

A
  • Squamous cell carcinomas: Below the dentate line
  • Remainder (~10%): adenocarcinomas - upper anal canal epithelium and the crypt glands
22
Q

What is anal intraepithelia neoplasia?

A
  • Precancerous condition that can affect either the perianal skin or anal canal, linked to the development of squamous cell carcinoma.
  • Strongly linked to infection with the human papilloma virus (HPV).
  • The grading of AIN is dependent on the degree of cytological atypia and the depth of that atypia in the epidermis. High-grade AIN (grade 2 or 3) is premalignant and may progress to invasive cancer.
23
Q

What are the RFs for developing anal cancer?

A
  • HPV infection ( 80-90% of cases, especially HPV-16 and HPV-18)
  • HIV/ syphilus
  • Increasing age
  • Smoking
  • Immunosuppression
  • Crohn’s disease
24
Q

What are the symptoms of anal cancer?

A
  • Rectal pain or rectal bleeding
  • Anal discharge
  • Pruritus
  • Presence of a palpable mass
  • Locally invasive disease: Perianal infection and fistula-in-ano
25
Q

How is anal cancer investigated?

A
  • Gold standard: proctoscopy
  • Examination under anaesthetic (EUA) + biopsy
  • Women: a smear test to exclude CIN + further biopsies if signs of vulval intraepithelial neoplasia (VIN) are present.
  • HIV test
  • Imaging
    • USS-guided Fine Needle Aspiration (FNA): of any palpable inguinal lymph nodes
    • CT thorax-abdomen-pelvis: distant metastases
    • MRI Pelvis: to assess the extent of local invasion (T stage)
26
Q

How is anal cancer managed?

What are some of the complications of this treatment?

A
  • 1st line: chemo-radiotherapy:
    • Treatment via external beam radiotherapy to the anal canal and inguinal lymph nodes
    • Dual-chemotherapy agents, such as mitomycin C and 5-fluorouracil.
  • Surgery: for advanced disease
    • Abdominoperineal resection (APR) mainly
    • For some a posterior or total pelvic exenteration is required.
  • Follow up: every 3–6 months for a period of 2 years

Complications:

  • Chemoradiation-related pelvic toxicity: can present with dermatitis, diarrhoea, proctitis, and/or cystitis.
  • Longer term: fertility issues, faecal incontinence, vaginal dryness, erectile dysfunction, and rectovaginal fistula