General Surgery Flashcards
List the causes of Acute Pancreatitis
Gall-stones
Ethanol
Trauma
Steroids Mumps Autoimmune Scorpion bite Hyperlipidaemia ERCP Diabetes
ALSO IDIOPATHIC
Why do you get fat necrosis with acute pancreatitis?
If caused by gallstones, duodenopancreatic reflux causes the activation of enzymes in the pancreatic duct.
Describe the presentation of acute pancreatitis
Pain - rapid onset, radiating to the back, severe and epigastric
Profuse vomiting
Give 5 signs of acute pancreatitis
Tachycardia Pallor (shock) Rigid abdomen Ileus Jaundice
What are the two skin changes seen in acute hemorrhagic pancreatitis
Grey turners sign - in the flanks
Cullen’s sign - around the umbilicus
What results of investigations would you see in acute pancreatitis?
Raised serum amylase Raised serum lipase ABG AXR - no psoas shadow/sentinel loop of proximal jejunum from ileus CT
Give the management of pancreatitis
NBM
Analgesia - Pethidine
Observations - every hour
Daily - FBC/U&E/Ca/Glucose/Amylase and ABG
Abscess/Necrosis - parenteral nutrition and laparotomy
Give four risk factors for chronic pancreatitis
Alcoholism
Malnutrition
Hereditary
Hypercalcemia
What investigations would you do for chronic pancreatitis?
AXR - calcifications
MRCP
ERCP - dilatation/irregular pancreatic duct and compression of bile duct by the pancreatic head
EUS
What are the non-surgical management options for chronic pancreatitis?
Analgesics - long term opiates
Diet - low fat diet with pancreatin
What are the surgical options for chronic pancreatitis?
Partial/total pancreatectomy
Roux-en-Y reconstruction
Whipple’s pancreaticoduodenectomy
Give 5 risk factors for pancreatic carcinoma
Smoking Alcoholism Carcinogens Diabetes mellitus Chronic pancreatitis
Give the common type of pancreatic tumour and the most likely locations.
Ductal adenocarcinoma
60% head
25% body
15% tail
What is the classical presentation of pancreatic cancer?
Painless, obstructive jaundice (Courvoisier’s law)
What is the most common presentation of pancreatic cancer?
Dull, aching epigastric pain that radiates to the back, relieved by sitting forwards
What imaging techniques would be useful in diagnosing pancreatic cancer?
US/CT - would show pancreatic mass +/- biliary dilatation +/- liver metastases
EUS is the best for diagnosis and staging
Give the common locations and presentations of a direct spread of a pancreatic tumour
Common bile duct - obstructive jaundice
Duodenum - occult/overt intestinal bleeding or obstruction
Portal vein - portal vein thrombosis/portal hypertension and ascites
IVC - bilateral leg oedema
What is the common presentation of cholangiocarcinoma?
Painless, progressive jaundice - dark urine and pale stools
Epigastric pain, steatorrhoea and weight loss
What imaging would be used in cholangiocarcinoma?
MRCP
ERCP ( can also stent at this point)
CT guided needle biopsy
Give the classical presentation of biliary colic
RUQ pain radiating to the back +/- jaundice
What is the standard treatment for biliary colic?
Laparoscopic cholecystectomy
What is the underlying pathology of acute cholecystitis?
Impaction of stone/sludge in the neck of the gallbladder.
What differs between acute cholecystitis and biliary colic?
Inflammatory component - raised WCC and fever
What is Murphy’s sign
Two fingers placed on RUQ (painful area). Patient asked to breath in deeply, pain is felt and inspiration halted when gallbladder impacts on hand.
Must be compared to the LUQ