General Surgery Flashcards

1
Q

Gastroesophogeal reflux

A

Vague sx, hard to distinguish. pH monitoring best. Typical case- overweight person, burning retrosternal pain, heartburn when bending over/tight clothes/flad in bed, relieved by antacids or h2 blockers. If long-standing history, concern = damage to lower esoph, possible Barret- do endoscopy/biopsy

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2
Q

Surgery for GERD

A

Appropriate in long-standing sx disease w/ no medical control. Necessary for ulceration or stenosis, or severe dysplastic changes. For latter, do resection, otherwise laparoscopic Nissen fundoplication. Verify acid reflux w/ pH, do endoscopy/biopsy to lower esoph, that lower esoph sphincter weak, do manometry and gastric emptying study, and a barrium swallow to see where esophagogastric jn is

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3
Q

Motility problems

A

Recognizable clin patterns- crushing pain w/ swallowing = uncoordinated massive contraction, dysphagia = achalasia (solids easier than liquids). D barium swallow then manometry

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4
Q

Achalasia

A

More common in woman, dysphagia worse for liquids, pt can sit up straight and wait to swallow. occasional regurg of food, x-ray shows MEGAESOPHAGUS. Dx w/ manometry, repeated dilatations or surgical myotomy (heller) for tx

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5
Q

Cancer of esophagus

A

Classic progression- dysphagia w/ meath, then solids, then soft foods, liquids, then several mo. saliva. Sig weight loss. Squam CC in men w/ somoking/drinking (esp in AA). Adenocarcinoma in long-standing GERD. Dx w/ endoscopy + biopsy, barium swallow first to prevent perforation. CT scan assesses operabiilty, often just palliative :(

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6
Q

Mallory Weiss tear

A

Prolonged forceful vom => BRB coming up. Endoscopy establishes dx, then photocoag

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7
Q

Boerhaave syndrome

A

Prolonged forceful vom => esoph perforation. Continous, severe wrenching epigastric/low sternal pain (sudden), then fever, leukocytosis + very sick pt. Swallow gastrografin (barium only if gg no work), then emergency surg repair. Delay is BAD

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8
Q

Instrumental perf of esophagus

A

Most common reason for perf, post endoscopy, sx develop. Emphysema in neck is dx, do contrast study + prompt repair

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9
Q

Gastric adenocarcinoma

A

More common in elderly. Arex, weight loss, vague epigastric distress, early satiety, occasional vom blood. Endo/biopsy for dx, then CT scan to assess operability. Surgry is best therapy

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10
Q

Gastric lymphoma

A

Almost as common as gastric adenocarcinoma. Tx w/ chemo/radiation. Surgery done if perforation feared as tumor melts. Low-graded lymphomatoid trans (MALTOMA) reversed by H. pylori erad

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11
Q

Mechanical intestinal obstruction

A

From adhesions from prior ex-lap. Colicky ab pain + protracted vom, progressive ab distention (if low obstruction), no poo or fart. Early- high-pitched bowel sounds and colikcy pain, then silence. xray w/ distented small bowel loops, air-fluid levels. Tx NPO, NG suction and Iv fluids, hope for spont resolution, watch for signs of strangu

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12
Q

Strangulated obstruction

A

Compromised blood supply, pt develops fever, leuko, constant pain, peritoneal irritation => periotnitis/sepsis. Emergency surgery required

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13
Q

Mech intestinal obstruction caused by incarcerated hernia

A

Same clinic picture as strangula, but with a hernia that’s no longer reducible. Do surgery to elim hernia but- emergently post rehydration if strangulation, electively in those that re reducible and have bowel

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14
Q

Carcinoid syndrome

A

Seen in pts w/ small bowel carcinoid tumor w/ liver mets. Diarrhea, face flush, wheezing, right-side vave damage. 24 hr urinary collection for 5hydroxyindolacetic acid for dx. If episodic, only high conc during attack

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15
Q

Acute appendicits

A

Anorexia, vague periumbilical pain => sharp, severe, constant, to RLQ. Tenderness, guarding, rebound to right/below belly. Modest fever and leukocytosis, neutrophilia/immature forms. If not classic pres, do a CT. Then surgery

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16
Q

Right colon cancer

A

Anemia (hypochromic, iron deficiency) in elderly, stool 4+ occult blood. Colonoscopy/biopsy dx, right hemicolectomy tx

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17
Q

Left colon cancer

A

Bloody bowel mvts, bload coats outside of stool, constipation, narrow stool. Flexible proctosigmoidoscopic exam + biopsy dx, then full colonoscopy to rule of synchronous secondary primary. CT scan to eval operability/extend. pre-op chemo/rads if large

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18
Q

Colonic polyps

A

Pre-malig possibility. Malignant potential most in familial polyposis (like Gardener), then villous adenoma, and last adenomatous polyp. Non-malig = juvenile, Peutz-Jegher, inflamm, and hyperplastic

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19
Q

Chronic ulcerative colitis (CUC)

A

manage medically. Surgical if longer than 20 years, severe interference w/ nutrition, multiple hopsitals, needing high dose steroids/immuno sup, or TOXIC MEGACOLON. Definitive treatment of CUC = remove colon, including rectal mucosa

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20
Q

Pseudomembranous enterocolitis

A

From c-dif, caused by clindamycin, or cephalos. Profuse watery diarrhea, cramps, fever, leuko. Look for toxin in stool, stop abx, no antidiarrheals, use metro, or vanco as alternate

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21
Q

Anorectal disease

A

rule out cancer by proper p/e (including proctosigmoidoscopic exam), even if it seems benign

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22
Q

Hemorrhoids

A

Bleed when internal 9tx rubber band ligation), hurt when external (need surgery if conservative fails). Internal hemmorhoids can be painful/itchy if prolapse

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23
Q

Anal fissure

A

Young women, pain w/ poop/ blood streaks on stool. fear of pain => not enough pooping, refuse exam, might need anesthesia. Fissue posterior at midline. Tight sphincter cause/perpetuates problem, so relax it w/ stool softener, topical nitroglycerin, botulin, dilatation or lateral internal sphincterotomy

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24
Q

Crohn’s (anal)

A

Starts w/ fissure/fistula/small ulceration, dx suspected if area fails to heal or gets worse after surgery (normally heals well)

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25
Ischiorectal abscess (perirectal)
Febrile, super perirectal pain (can't sit down or poop). P/e shows classif abscess lateral to anus, need I&D, rule out cancer w/ proper exam. if idabetes, could get bad necrotizing after, so watch
26
Fistula in ano
Post perirectal abscess, epithelial migration from anal crypts and perineal skin make a permane ttract. pt has fecal soiling and occasional perineal discomfort. P/e shows opening/openings lateral to anus. Cordlike tract, discharge expressed. rule out necrosis/draining tumor, treat w/ fistulotomy
27
squam cell carcinoma of anus
more common in HIV+ or homosexuals w/ receptive sex, fungating mass grows out of anus, mets in inguinal nodes. dx w/ biopsy, tx with nigro chemorads then surgery if residual
28
General GI bleed stats
3/4 upper Gi, 1/4 in colon/rectum, few in jejunum/ileum Gi colon bleeds from angiodysplasia, polyps, divertic, cancer (old ppl). Hemorrhoids more common w/ age. Old person bleed = could be anywhere young person GI bleed= upper GI (more likely) Stats for when blood is per rectum
29
Vomiting blood
Upper GI (nose to lig of treitz). Also if blood in NG tube when bleeding per rectum. Otherwise upper GI endoscopy
30
Melena
Digested blood, so it is high up. Uper GI endoscopy
31
red blood per rectum
Come from anywhere (upper Gi if came down too fast). Dx w/ NG tube if actively bleeding (bloody means its upper Gi). No blood in NG w/ white flluid? Check duod w/ upper Gi endo. No blood w/ yellow fluid (bile), then it can't be upper Gi at all
32
Active bleeding per rectum, not upper GI
Harder work up. exclud bleeding hemorrrhoids w/ anoscopy, colonscopy not helpful during active bleeding. Two options- if bleeding more then 2ml/min, angiogram + embolization. If less than .5 ml/min, wait till bleding stops, then colonscopy. In-between, do tagged red cell study, if it puddles, angiogram. Slow test though, so pt might not be bleeding by the end. But could guide a hemicolectomy in future. Or do a colonscopy later
33
Recent hx of blood per rectum?
if young, do Upper Gi, if old, then do full Gi endo
34
Blood per rectum in child
Most likely Meckel's. workup w/ technetium scan, look for actopic gastric mucosa
35
Massive upper Gi bleed
stressed, multiple trauma, or post-op pt from stress ulcers. dx w/ endo, then angio embo, or avoid by maintaining gastric pH above 4
36
Acute ab pain
perforation, obstruction, inflamm, or ischemia
37
Perf ab pain
Sudden onset, constant/generalized/very severe. Won't move, protects abdomen. Except in v old/sick, general peritonitis. Free air under diaphragm in upright x ray = dx. Perf peptic ulcer most common. SURGERY
38
Obstructive acute ab pain
sudden colikcy pian, typical location/radiation. pt moves constantly, seeking comfortable position. few physical findings
39
Inflamm acute abdomen
Gradual onset, slow build up at least 6 hrs, constant, starts ill-defined, locates to area over time, typical rads pattern. p/e of peritoneal irritation in affected area + systemic signs (leuko + fever), except in pancreatitis
40
Ischemic process
Combine severe ab pain + blood in gut lumen
41
Primary peritonitis
Child w/ nephrosis + ascites or adult w/ ascites + mild acute abdomen and mabes fever/leuko. Ascitic culture shows single organism (in normal acute ab, many orgs.) Tx w/ abx, not surg
42
Tx for general acute ab
Ex-lap, no need for specific dx. if not primary peritonitis, rule out mimics of acute ab (MI, lower lobe pneumo (CXR), PE (immobile patient), and rule out non-surg things (pancreatitis and urinary stones)
43
Acute pancreatitis
Alcoholic w/ upper acute abdomen. Classic- rapid onset inflamm, constant, epigastric, radiating through to back, nausea/vom/retching. P/e findings in upper abdomen, modest. Dx w/ serum/urinary amylase or lipase (serum 12-48 hrs, urine if 3-6days). Ct if unclear. tx = NPO, NG suction, Iv fluids
44
Biliary tract disease
Fat woman, forties, 55 children, RUQ ab pain
45
Ureteral stones
Sudden colicky flank pain radiating to inner thigh/scrotum/labia, sometimes urinary symptoms of urgency/frequency, microhemat in UA. Xray shows stone, CT even better
46
Acute diverticulitis
LLQ pain (one of few! tubes/ovary in women). Pt = middle-age/beyond/ fever, leuk, p/e of peritoneal in LLQ, palpable tender mass. Ct dx, tx = npo, iv, abx. Most cool down, surg if not, elective surg if 2+ attacks
47
Volvulus of sigmoid
Old people, signs of intestinal ob and severe ab distention, x-rays dx, show air-fluid levels in small bowel, distended colon, air-filled loop in RUQ that tapers down to LLQ (parrots beak shape). Proctosigmoidscopic exam resolves acute problem. Leave rectal tube, recurrence? do elective sig resection
48
Mesenteric ischemia
Old ppl, develop acute ab in someone w/ a-fib or recent MI (clot from SMA). Very old dont show super acute abdomen, so late dx, w/ blood in bowel lumen + acidosis and sepsis. If early case, arterio embo saves day!
49
Primary hepatroma (hepatocellular carcinoma)
in US, only w/ cirrhosis. vague RUQ discomfort, weight loss. Spcific blood marker = alpha-feto protein. CT scan shows location/extent, resection done if possible
50
Mets to liver
More common than primary cancer (20:1). Found by CT f/u for 1st tumor, or b/c of rising CEA in colonic cancer. If slow growing and confined to one lobe, can resect, otherwise radioablation
51
Hepatic adenoma
complication of OCP, can rupture and bleed massively in abdomen. Dx CT, emergency surgery
52
Pyogenic liver abscess
Complication of biliary tract disease (Acute ascending cholangitis). Pt develops fevr, leuko, tender liver. Sonogram/CT dx, percutaneous drainage reqd
53
Amebic abscess of liver
Men w/ mexico connection. Presentation and imaging dx similar, tx w/ metro (rarely needs drainage). Def dx froms erology (ameba not in pus), but takes 2 weeks, so just tx empirically. If improve, no drain
54
Hemolytic jaundice
Low level (bili of 6 or 8), all unconjugated (indirect), no elevation of other, no bile in urine. W/u for why hemolysis
55
Obstructive jaundice
Elevation of both types of bili, lil elev of transaminase, very high alk phosphatase. First, sonogram, look for dilatation of biliary ducts, also why. If stone, can't see stone in common bile duct but can see them in gallbladder (can't dilate). If malignant obstruct, large, thin-walled distended gallbladder often (Courvoisier-terrier sign)
56
Obstructive jaundice from stones
Obese, fecund woman in forties with high alk phsoph, dilated sonogram ducts, nondil gallblader w/ stones. Do ERCP to dx, sphincterotomy, and remove duct stone. Then cholecystectomy
57
Obs. Jaundice from Tumor
Cause- adenocarcinoma of head of pan, ampulla of Vater or cholangiocarcinoma from common duct Dx- snoogram w/ dilated gallbladder, then CT (panc cancers show up), then perc biopsy. If CT neg, ERCP next. Other cancers are smaller, but show in ERCP
58
Ampullary Cancers
If malig obstructive jaundice w/ anemia + blood in stool. can bleed into lumen and obstruct biliary flow at once. Do endoscopy first. 40% cure rate
59
Pancreatic cancer
Seldom cured, even with whipple (pancreatodudenotomy).
60
Gallstones
Responsible for majority of biliary tract pathology, spectrum of disease, 4 Fs, more common in mexican and native americans. Leave asx alone!
61
Biliary colic
Stone in cystic duct, tempt occlusion. colicky pain in RUQ, to right shoulder and beltlike to back, after fatty food. Naus/vom, but no peritonitis or systemic. self-limt (10-30 min), stopped by anticholinergics. Sonogram dx, elective surg if ya want
62
Acute cholecystitis
Biliary colic, but then stone stays in duct, inflamm process. Constant pain, modest fever/leuk, peritonitis in RUQ. Minimal change in liver fn. Sonogram dx- stones + thick gallbladder, pericholecystic flui. HIDA shows uptake not to gallbladder. Tx = NG suction, NPO, IV fluids, abx cooldown, elective removal later. No response? emergency lap chole, or temporize with emerg perc. transhepatic cholecystotomy (DRAIN)
63
Acute ascending cholangitis
DEADLY, stones partially block common duct => ascending infection up the duct. Old and very sick, high fever, chills, high WBC (sepsis), some high bili,key = high alk phosoph. Give IV abx + emergency decomp of common duct (ERCP or PTC or surgery). eventual cholecystectomy
64
Obstructive jaundice w/ no cholangitis
Stones COMPLETELY block biliary obstruction
65
Biliary pancreatitis
Stones impacted in ampulla, obstruct panc and bili ducts. Often pass spontaneously, w/ mild/short episode of cholangitis + pancreatitis. Sonogram dx gallstones, tx conservatively, if not, ERCP and sphincterotomy to dislodge
66
Acute pancreatitis
Complication of gallstones, or alcoholics. Edematous, hemorrhagic, suppurative (abscess). => later panc pseudocyst or chronic pancreatitis
67
Acute edematous pancreatitis
Alcoholic/gallstones pt. Epigastric/mid ab pain after heavy meal or alcohol, constant, radiates thru back, w/ nause, vom, and retching. tenderness/mild rebund in upper ab. High serum amylase/lipase (urinary later). Know it's edematous w/ elevated hematocrit. resolution follows few days of panc rest (NPO<, NG, IV)
68
Acute hemorrhagic pancreatitis
More deadly, starts edematous, but lower hematocrit = a clue. Also see rnason's criteria- early elevated WBC and blood glucose, low serum clalcium. Hematocrit lowers by next morning, and calcium low despite tx, BUN up, mets acidosis + low arterial PO2. Terrible progrnosis, need ICU. => multiple panc abscesses, try to anticipate/drain w/ daily CT scans
69
Pancreatic abscess (suppurative)
Someoen not getting CT scans, w/ fever + leuko after 10 days of pancreatitis. see pus collections in imaging, do perc drainage
70
Pseudocyst (panc)
Late sequela of acute panc or panc upper abdominal trauma, in 5 weeks you see a pseudoscyst, juice outside the ducts (often lesser sac), pressure symptoms (early satiety, vague discomfort, deep palpable mass). DxCT or sonogram. Tx by size/age of psedocyst, smaller than 6 cm or younger than 6 weeksis a-ok, but too big or old means tx- drain it! perc or surg or endoscopically
71
Chronic pancreatitis
Devastating disease, esp in alcoholics, get a calcified burned-out pancreas, steatorrhea, diabetes, and epigastric pain. Diabetes/steatorrhea controled with insulin + panc enzymes, but the pain SUCKS. ERCp shows specific pts of obstruction/dilitation, drain pancreatic duct maybe
72
Abdominal hernias
electively repair to avoid risk of intestinal obstruction/strangulation, except for umbilical hernias in young patients under 2, and esoph sliding hiatal hernias (not true). Irreducible hernias need emergency surg to prevent strang, those that were always irreducible for years need elective repair only
73
How to rule out cancer in breast disease
Get tissue from pathologist. Age is best correlator, quite possible by middle age, very like in old or w/ fam hx
74
Mammography
Adjunct to p/e, start at age 40, earlier if fam hx, cant do before 20 or during lactation, can be done during pregos. Mammo guided multiple core biopsy are best way to biopsy breast masses
75
Fibroadenomas
Young women (teens, early twenties), firm, rubbery mass, moves easily. Do FNA or sonogram to dx. Can remove if ya want
76
Giant Juvenile Fibroadenomas
in very young adolescents, very rapid growth, remove to avoid deformity/distortion
77
Cystosarcoma phyllodes
Late 20s, grow over many years, get real big, replace/distort entire breat, not invasive/becoming fixed. Most benign, but could become sarcoma. Do biopsy, and def remove
78
Mammary dysplasia (fibrocystic disease, cystic mastitis)
30s and 40s (not after menopause), bilat tenderness with MC + multiple lumps that follow MC. No dom/persistent mass, do mammo, if persistent mass, gotta do aspiration. Clear fluid and mass goes away? Dunzo. Mass persists/recurs, do formal biopsy. Bloody fluid? Send to cyto!
79
Intraductal papilloma
Young women (20-40), bloody nipple discharge. Mammogram to look for other lesions, but wont show papilloma. Use galactogram for dx, guide surgical resection
80
Breast abscess
Only in lactating women, do i&d, but biopsy abscess wall jic
81
Breast cancer
Think it in any woman w/ a palpable breast mass. Also ill-defined fixed mass, orange peel skin, retrac of nipple, eczematoid lesions of areola, reddish orange peel skin over mass, palpable axillary nodes. Trauma does not rule out cancer
82
Breast cancer in pregos
Dx same way as if not pregnant, tx same except no rads during preg, and no chemo during first tri. keep baby alive!
83
Mammograms w/ breast cancer show
Irregular area of increased density w/ fine microcalcifications that wudn't there before
84
Treatment of resectable breast cancer
Starts w/ lumpectomy + axillary sampling + post-op rads,or modified radical mastectomy. Former only when tumor is small in relatively large breast away from nipple
85
Infiltrating ductal carcinoma
standard form! inflamm cancer is only variant that is much worse. Other variants (lobal, medullary mucinous) have slightly better prognosis, tx same way as standard. Lobular might be more bilateral (but not enough to just chop both off)
86
Ductal carcinoma in situ
CANNOT mets! But very high incidence of recurrence w/ only local excision, so do total simple masectomy for multicentric lesions, or lumpectomy if its all in one quarter
87
Inoperable cancer of breast
Chemo (maybe rads), inoperable based on local extent (not mets)
88
Adjuvant systemic therapy
Post surgery in all pts, esp if axillary nodes +. Chemo, or hormonal if receptor positive. premenopausal women get tramoxifen, post menopausal get anastrozole. Frail old women w/ tumors that aren't too bad should just get hormones!
89
Persistent h/a or back pain in breast cancer pt?
METS! Do ct for brain mets, bone scan + x-ray (in pedicles). Radiation + braces
90
Thryoid nodules
In euthyroid pts could be cancer (but low incidence so don't just chop it) If benign, follow but no intervent If malignant/indeterminate, do lobectomy, then do frozen section Total removal if follicular cancers, then tx w/ radioactive iodine later to get the blood-borne mets
91
Thyroid nodules in hyperthyroid pts
Almost never cancer, might be hot. Clinical signs = weight loss (but ravenous appetite), palpitations, heat intolerance, moist skin, fidgety, tachycardia, a-fid/flutter, cofirm w/ TSH low or T4 high. Nuke scan shows nodule, tx w/ radioactive iodine or surg the hot adenoma
92
Hyperparathyroidism
Serendipitous discovery of high serum calcium! Repeat calc, look for low phosph, rule out bone mets. If persists, do PTH determination (in light of calcium levels). Asx pts get sx at 20%/year, so elective intervention can make sense. Removal = curative, single adenoma
93
Cushing
Round, ruddy, hairy face, buffalo hump, fat pads supra clav, obese trunk + abdominal stria, thin weak extremities, osteoporosis, diabetes, HTN, mental instability. W/u w/ low-dose dexameth suppression test. Suppressed at low dose = no disease. If no supression, do 24 hr urine cortisol (if elevated), do high-dose suppression test. If suppressed, high dose pit microadenoma. No suppresion at either dose = adrenal adenoma! Image (MRI pit CT adrenal) and remove. Also a mayo clinic algorithim, look for free urine cortisol and corticotropin levels
94
ZES (gastrinoma)
Shows up as virulent peptic ulcer diseases, resistant and too extensive (too many ulcers!) also watery diarrhea. Measure gastrin, look for tumor w/ CT of panc. remove. Also omeprazole for mets disease
95
Insulinoma
CNS symptoms b/c of low blood sugar when pt fasting. Ddx is reactive hypoglycemia (after eating) and self-admin of insulin. Plasma assay for disease = high hinsulin and high C, if just insuling, C is low. Do CT of pancreas/locate tumor
96
Nesidioblastosis
Devastating hypersecretion of insulin in newborn, needs 95% pancreatectomy (NO!)
97
Glucagonoma
Severe migratory necrolytic dermatitis, resistant to therapy, in pt w/ mild diabetes, some anemia, glossitis and stomatitis. Glucagon assay dx, Ct to locate, resect is curative. For inoperable, give somatostatin and streptozocin.
98
Primary hyperaldo
Adenoma or hyperplasia. You see: hypoK in HTN female pt NOT on diuretics, some hyperNa, and met ALK. Aldo levels high, renin low. Postural changes (more aldo when upright) suggests hyperplasia, but lack of response is adenoma. Adrenal CT localize, surgical removal
99
Pheochromocytoma
Thin, hyperactive women w/ attacks of pounding headache, perspiration, palp, pallor (and extremely high BP). Attacks can subside, not always sustained. start w/u w/ 24 hr urinary determination of VMA or metanephrine (more specific). Follow w/ CT of adrenal glands or radionuke studies if extradrenal chance. Tumors usually big...BE CAREFUL WITH SURGERY...alpha blockers!
100
Coarctation of the aorta
Young, htn in arms w/ normal or low or no pressure, CXR shows scalloping of ribs (erosion for large collateral intercostals). Do CT or MRI angio, maybe arteriogram unnecessary. Surgical correction curative
101
Renovascular HTN
Two distinct groups- young women w/ fibromuscular dysplacia or old men w/ arteriosclerotic occlusive disease. Either way, HTn resistant to usual meds, and telltale faint bruit over flank or upper abdomen. W/u of scanning + doppler of renal vessels + arteriographic visualization. therapy imperative in yong women (ballon dilatation + stenting) but more controversial in old men!