General Surgery Flashcards

1
Q

Gastroesophogeal reflux

A

Vague sx, hard to distinguish. pH monitoring best. Typical case- overweight person, burning retrosternal pain, heartburn when bending over/tight clothes/flad in bed, relieved by antacids or h2 blockers. If long-standing history, concern = damage to lower esoph, possible Barret- do endoscopy/biopsy

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2
Q

Surgery for GERD

A

Appropriate in long-standing sx disease w/ no medical control. Necessary for ulceration or stenosis, or severe dysplastic changes. For latter, do resection, otherwise laparoscopic Nissen fundoplication. Verify acid reflux w/ pH, do endoscopy/biopsy to lower esoph, that lower esoph sphincter weak, do manometry and gastric emptying study, and a barrium swallow to see where esophagogastric jn is

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3
Q

Motility problems

A

Recognizable clin patterns- crushing pain w/ swallowing = uncoordinated massive contraction, dysphagia = achalasia (solids easier than liquids). D barium swallow then manometry

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4
Q

Achalasia

A

More common in woman, dysphagia worse for liquids, pt can sit up straight and wait to swallow. occasional regurg of food, x-ray shows MEGAESOPHAGUS. Dx w/ manometry, repeated dilatations or surgical myotomy (heller) for tx

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5
Q

Cancer of esophagus

A

Classic progression- dysphagia w/ meath, then solids, then soft foods, liquids, then several mo. saliva. Sig weight loss. Squam CC in men w/ somoking/drinking (esp in AA). Adenocarcinoma in long-standing GERD. Dx w/ endoscopy + biopsy, barium swallow first to prevent perforation. CT scan assesses operabiilty, often just palliative :(

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6
Q

Mallory Weiss tear

A

Prolonged forceful vom => BRB coming up. Endoscopy establishes dx, then photocoag

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7
Q

Boerhaave syndrome

A

Prolonged forceful vom => esoph perforation. Continous, severe wrenching epigastric/low sternal pain (sudden), then fever, leukocytosis + very sick pt. Swallow gastrografin (barium only if gg no work), then emergency surg repair. Delay is BAD

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8
Q

Instrumental perf of esophagus

A

Most common reason for perf, post endoscopy, sx develop. Emphysema in neck is dx, do contrast study + prompt repair

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9
Q

Gastric adenocarcinoma

A

More common in elderly. Arex, weight loss, vague epigastric distress, early satiety, occasional vom blood. Endo/biopsy for dx, then CT scan to assess operability. Surgry is best therapy

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10
Q

Gastric lymphoma

A

Almost as common as gastric adenocarcinoma. Tx w/ chemo/radiation. Surgery done if perforation feared as tumor melts. Low-graded lymphomatoid trans (MALTOMA) reversed by H. pylori erad

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11
Q

Mechanical intestinal obstruction

A

From adhesions from prior ex-lap. Colicky ab pain + protracted vom, progressive ab distention (if low obstruction), no poo or fart. Early- high-pitched bowel sounds and colikcy pain, then silence. xray w/ distented small bowel loops, air-fluid levels. Tx NPO, NG suction and Iv fluids, hope for spont resolution, watch for signs of strangu

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12
Q

Strangulated obstruction

A

Compromised blood supply, pt develops fever, leuko, constant pain, peritoneal irritation => periotnitis/sepsis. Emergency surgery required

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13
Q

Mech intestinal obstruction caused by incarcerated hernia

A

Same clinic picture as strangula, but with a hernia that’s no longer reducible. Do surgery to elim hernia but- emergently post rehydration if strangulation, electively in those that re reducible and have bowel

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14
Q

Carcinoid syndrome

A

Seen in pts w/ small bowel carcinoid tumor w/ liver mets. Diarrhea, face flush, wheezing, right-side vave damage. 24 hr urinary collection for 5hydroxyindolacetic acid for dx. If episodic, only high conc during attack

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15
Q

Acute appendicits

A

Anorexia, vague periumbilical pain => sharp, severe, constant, to RLQ. Tenderness, guarding, rebound to right/below belly. Modest fever and leukocytosis, neutrophilia/immature forms. If not classic pres, do a CT. Then surgery

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16
Q

Right colon cancer

A

Anemia (hypochromic, iron deficiency) in elderly, stool 4+ occult blood. Colonoscopy/biopsy dx, right hemicolectomy tx

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17
Q

Left colon cancer

A

Bloody bowel mvts, bload coats outside of stool, constipation, narrow stool. Flexible proctosigmoidoscopic exam + biopsy dx, then full colonoscopy to rule of synchronous secondary primary. CT scan to eval operability/extend. pre-op chemo/rads if large

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18
Q

Colonic polyps

A

Pre-malig possibility. Malignant potential most in familial polyposis (like Gardener), then villous adenoma, and last adenomatous polyp. Non-malig = juvenile, Peutz-Jegher, inflamm, and hyperplastic

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19
Q

Chronic ulcerative colitis (CUC)

A

manage medically. Surgical if longer than 20 years, severe interference w/ nutrition, multiple hopsitals, needing high dose steroids/immuno sup, or TOXIC MEGACOLON. Definitive treatment of CUC = remove colon, including rectal mucosa

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20
Q

Pseudomembranous enterocolitis

A

From c-dif, caused by clindamycin, or cephalos. Profuse watery diarrhea, cramps, fever, leuko. Look for toxin in stool, stop abx, no antidiarrheals, use metro, or vanco as alternate

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21
Q

Anorectal disease

A

rule out cancer by proper p/e (including proctosigmoidoscopic exam), even if it seems benign

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22
Q

Hemorrhoids

A

Bleed when internal 9tx rubber band ligation), hurt when external (need surgery if conservative fails). Internal hemmorhoids can be painful/itchy if prolapse

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23
Q

Anal fissure

A

Young women, pain w/ poop/ blood streaks on stool. fear of pain => not enough pooping, refuse exam, might need anesthesia. Fissue posterior at midline. Tight sphincter cause/perpetuates problem, so relax it w/ stool softener, topical nitroglycerin, botulin, dilatation or lateral internal sphincterotomy

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24
Q

Crohn’s (anal)

A

Starts w/ fissure/fistula/small ulceration, dx suspected if area fails to heal or gets worse after surgery (normally heals well)

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25
Q

Ischiorectal abscess (perirectal)

A

Febrile, super perirectal pain (can’t sit down or poop). P/e shows classif abscess lateral to anus, need I&D, rule out cancer w/ proper exam. if idabetes, could get bad necrotizing after, so watch

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26
Q

Fistula in ano

A

Post perirectal abscess, epithelial migration from anal crypts and perineal skin make a permane ttract. pt has fecal soiling and occasional perineal discomfort. P/e shows opening/openings lateral to anus. Cordlike tract, discharge expressed. rule out necrosis/draining tumor, treat w/ fistulotomy

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27
Q

squam cell carcinoma of anus

A

more common in HIV+ or homosexuals w/ receptive sex, fungating mass grows out of anus, mets in inguinal nodes. dx w/ biopsy, tx with nigro chemorads then surgery if residual

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28
Q

General GI bleed stats

A

3/4 upper Gi, 1/4 in colon/rectum, few in jejunum/ileum
Gi colon bleeds from angiodysplasia, polyps, divertic, cancer (old ppl). Hemorrhoids more common w/ age. Old person bleed = could be anywhere
young person GI bleed= upper GI (more likely)
Stats for when blood is per rectum

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29
Q

Vomiting blood

A

Upper GI (nose to lig of treitz). Also if blood in NG tube when bleeding per rectum. Otherwise upper GI endoscopy

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30
Q

Melena

A

Digested blood, so it is high up. Uper GI endoscopy

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31
Q

red blood per rectum

A

Come from anywhere (upper Gi if came down too fast). Dx w/ NG tube if actively bleeding (bloody means its upper Gi).
No blood in NG w/ white flluid? Check duod w/ upper Gi endo.
No blood w/ yellow fluid (bile), then it can’t be upper Gi at all

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32
Q

Active bleeding per rectum, not upper GI

A

Harder work up. exclud bleeding hemorrrhoids w/ anoscopy, colonscopy not helpful during active bleeding. Two options- if bleeding more then 2ml/min, angiogram + embolization. If less than .5 ml/min, wait till bleding stops, then colonscopy. In-between, do tagged red cell study, if it puddles, angiogram. Slow test though, so pt might not be bleeding by the end. But could guide a hemicolectomy in future. Or do a colonscopy later

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33
Q

Recent hx of blood per rectum?

A

if young, do Upper Gi, if old, then do full Gi endo

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34
Q

Blood per rectum in child

A

Most likely Meckel’s. workup w/ technetium scan, look for actopic gastric mucosa

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35
Q

Massive upper Gi bleed

A

stressed, multiple trauma, or post-op pt from stress ulcers. dx w/ endo, then angio embo, or avoid by maintaining gastric pH above 4

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36
Q

Acute ab pain

A

perforation, obstruction, inflamm, or ischemia

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37
Q

Perf ab pain

A

Sudden onset, constant/generalized/very severe. Won’t move, protects abdomen. Except in v old/sick, general peritonitis. Free air under diaphragm in upright x ray = dx. Perf peptic ulcer most common. SURGERY

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38
Q

Obstructive acute ab pain

A

sudden colikcy pian, typical location/radiation. pt moves constantly, seeking comfortable position. few physical findings

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39
Q

Inflamm acute abdomen

A

Gradual onset, slow build up at least 6 hrs, constant, starts ill-defined, locates to area over time, typical rads pattern. p/e of peritoneal irritation in affected area + systemic signs (leuko + fever), except in pancreatitis

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40
Q

Ischemic process

A

Combine severe ab pain + blood in gut lumen

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41
Q

Primary peritonitis

A

Child w/ nephrosis + ascites or adult w/ ascites + mild acute abdomen and mabes fever/leuko. Ascitic culture shows single organism (in normal acute ab, many orgs.) Tx w/ abx, not surg

42
Q

Tx for general acute ab

A

Ex-lap, no need for specific dx. if not primary peritonitis, rule out mimics of acute ab (MI, lower lobe pneumo (CXR), PE (immobile patient), and rule out non-surg things (pancreatitis and urinary stones)

43
Q

Acute pancreatitis

A

Alcoholic w/ upper acute abdomen. Classic- rapid onset inflamm, constant, epigastric, radiating through to back, nausea/vom/retching. P/e findings in upper abdomen, modest. Dx w/ serum/urinary amylase or lipase (serum 12-48 hrs, urine if 3-6days). Ct if unclear. tx = NPO, NG suction, Iv fluids

44
Q

Biliary tract disease

A

Fat woman, forties, 55 children, RUQ ab pain

45
Q

Ureteral stones

A

Sudden colicky flank pain radiating to inner thigh/scrotum/labia, sometimes urinary symptoms of urgency/frequency, microhemat in UA. Xray shows stone, CT even better

46
Q

Acute diverticulitis

A

LLQ pain (one of few! tubes/ovary in women). Pt = middle-age/beyond/ fever, leuk, p/e of peritoneal in LLQ, palpable tender mass. Ct dx, tx = npo, iv, abx. Most cool down, surg if not, elective surg if 2+ attacks

47
Q

Volvulus of sigmoid

A

Old people, signs of intestinal ob and severe ab distention, x-rays dx, show air-fluid levels in small bowel, distended colon, air-filled loop in RUQ that tapers down to LLQ (parrots beak shape). Proctosigmoidscopic exam resolves acute problem. Leave rectal tube, recurrence? do elective sig resection

48
Q

Mesenteric ischemia

A

Old ppl, develop acute ab in someone w/ a-fib or recent MI (clot from SMA). Very old dont show super acute abdomen, so late dx, w/ blood in bowel lumen + acidosis and sepsis. If early case, arterio embo saves day!

49
Q

Primary hepatroma (hepatocellular carcinoma)

A

in US, only w/ cirrhosis. vague RUQ discomfort, weight loss. Spcific blood marker = alpha-feto protein. CT scan shows location/extent, resection done if possible

50
Q

Mets to liver

A

More common than primary cancer (20:1). Found by CT f/u for 1st tumor, or b/c of rising CEA in colonic cancer. If slow growing and confined to one lobe, can resect, otherwise radioablation

51
Q

Hepatic adenoma

A

complication of OCP, can rupture and bleed massively in abdomen. Dx CT, emergency surgery

52
Q

Pyogenic liver abscess

A

Complication of biliary tract disease (Acute ascending cholangitis). Pt develops fevr, leuko, tender liver. Sonogram/CT dx, percutaneous drainage reqd

53
Q

Amebic abscess of liver

A

Men w/ mexico connection. Presentation and imaging dx similar, tx w/ metro (rarely needs drainage). Def dx froms erology (ameba not in pus), but takes 2 weeks, so just tx empirically. If improve, no drain

54
Q

Hemolytic jaundice

A

Low level (bili of 6 or 8), all unconjugated (indirect), no elevation of other, no bile in urine. W/u for why hemolysis

55
Q

Obstructive jaundice

A

Elevation of both types of bili, lil elev of transaminase, very high alk phosphatase. First, sonogram, look for dilatation of biliary ducts, also why. If stone, can’t see stone in common bile duct but can see them in gallbladder (can’t dilate).
If malignant obstruct, large, thin-walled distended gallbladder often (Courvoisier-terrier sign)

56
Q

Obstructive jaundice from stones

A

Obese, fecund woman in forties with high alk phsoph, dilated sonogram ducts, nondil gallblader w/ stones. Do ERCP to dx, sphincterotomy, and remove duct stone. Then cholecystectomy

57
Q

Obs. Jaundice from Tumor

A

Cause- adenocarcinoma of head of pan, ampulla of Vater or cholangiocarcinoma from common duct
Dx- snoogram w/ dilated gallbladder, then CT (panc cancers show up), then perc biopsy. If CT neg, ERCP next. Other cancers are smaller, but show in ERCP

58
Q

Ampullary Cancers

A

If malig obstructive jaundice w/ anemia + blood in stool. can bleed into lumen and obstruct biliary flow at once. Do endoscopy first. 40% cure rate

59
Q

Pancreatic cancer

A

Seldom cured, even with whipple (pancreatodudenotomy).

60
Q

Gallstones

A

Responsible for majority of biliary tract pathology, spectrum of disease, 4 Fs, more common in mexican and native americans. Leave asx alone!

61
Q

Biliary colic

A

Stone in cystic duct, tempt occlusion. colicky pain in RUQ, to right shoulder and beltlike to back, after fatty food. Naus/vom, but no peritonitis or systemic. self-limt (10-30 min), stopped by anticholinergics. Sonogram dx, elective surg if ya want

62
Q

Acute cholecystitis

A

Biliary colic, but then stone stays in duct, inflamm process. Constant pain, modest fever/leuk, peritonitis in RUQ. Minimal change in liver fn. Sonogram dx- stones + thick gallbladder, pericholecystic flui. HIDA shows uptake not to gallbladder.
Tx = NG suction, NPO, IV fluids, abx cooldown, elective removal later.
No response? emergency lap chole, or temporize with emerg perc. transhepatic cholecystotomy (DRAIN)

63
Q

Acute ascending cholangitis

A

DEADLY, stones partially block common duct => ascending infection up the duct. Old and very sick, high fever, chills, high WBC (sepsis), some high bili,key = high alk phosoph. Give IV abx + emergency decomp of common duct (ERCP or PTC or surgery). eventual cholecystectomy

64
Q

Obstructive jaundice w/ no cholangitis

A

Stones COMPLETELY block biliary obstruction

65
Q

Biliary pancreatitis

A

Stones impacted in ampulla, obstruct panc and bili ducts. Often pass spontaneously, w/ mild/short episode of cholangitis + pancreatitis. Sonogram dx gallstones, tx conservatively, if not, ERCP and sphincterotomy to dislodge

66
Q

Acute pancreatitis

A

Complication of gallstones, or alcoholics. Edematous, hemorrhagic, suppurative (abscess). => later panc pseudocyst or chronic pancreatitis

67
Q

Acute edematous pancreatitis

A

Alcoholic/gallstones pt. Epigastric/mid ab pain after heavy meal or alcohol, constant, radiates thru back, w/ nause, vom, and retching. tenderness/mild rebund in upper ab. High serum amylase/lipase (urinary later). Know it’s edematous w/ elevated hematocrit. resolution follows few days of panc rest (NPO<, NG, IV)

68
Q

Acute hemorrhagic pancreatitis

A

More deadly, starts edematous, but lower hematocrit = a clue. Also see rnason’s criteria- early elevated WBC and blood glucose, low serum clalcium. Hematocrit lowers by next morning, and calcium low despite tx, BUN up, mets acidosis + low arterial PO2. Terrible progrnosis, need ICU. => multiple panc abscesses, try to anticipate/drain w/ daily CT scans

69
Q

Pancreatic abscess (suppurative)

A

Someoen not getting CT scans, w/ fever + leuko after 10 days of pancreatitis. see pus collections in imaging, do perc drainage

70
Q

Pseudocyst (panc)

A

Late sequela of acute panc or panc upper abdominal trauma, in 5 weeks you see a pseudoscyst, juice outside the ducts (often lesser sac), pressure symptoms (early satiety, vague discomfort, deep palpable mass). DxCT or sonogram. Tx by size/age of psedocyst, smaller than 6 cm or younger than 6 weeksis a-ok, but too big or old means tx- drain it! perc or surg or endoscopically

71
Q

Chronic pancreatitis

A

Devastating disease, esp in alcoholics, get a calcified burned-out pancreas, steatorrhea, diabetes, and epigastric pain. Diabetes/steatorrhea controled with insulin + panc enzymes, but the pain SUCKS. ERCp shows specific pts of obstruction/dilitation, drain pancreatic duct maybe

72
Q

Abdominal hernias

A

electively repair to avoid risk of intestinal obstruction/strangulation, except for umbilical hernias in young patients under 2, and esoph sliding hiatal hernias (not true). Irreducible hernias need emergency surg to prevent strang, those that were always irreducible for years need elective repair only

73
Q

How to rule out cancer in breast disease

A

Get tissue from pathologist. Age is best correlator, quite possible by middle age, very like in old or w/ fam hx

74
Q

Mammography

A

Adjunct to p/e, start at age 40, earlier if fam hx, cant do before 20 or during lactation, can be done during pregos. Mammo guided multiple core biopsy are best way to biopsy breast masses

75
Q

Fibroadenomas

A

Young women (teens, early twenties), firm, rubbery mass, moves easily. Do FNA or sonogram to dx. Can remove if ya want

76
Q

Giant Juvenile Fibroadenomas

A

in very young adolescents, very rapid growth, remove to avoid deformity/distortion

77
Q

Cystosarcoma phyllodes

A

Late 20s, grow over many years, get real big, replace/distort entire breat, not invasive/becoming fixed. Most benign, but could become sarcoma. Do biopsy, and def remove

78
Q

Mammary dysplasia (fibrocystic disease, cystic mastitis)

A

30s and 40s (not after menopause), bilat tenderness with MC + multiple lumps that follow MC. No dom/persistent mass, do mammo, if persistent mass, gotta do aspiration. Clear fluid and mass goes away? Dunzo. Mass persists/recurs, do formal biopsy. Bloody fluid? Send to cyto!

79
Q

Intraductal papilloma

A

Young women (20-40), bloody nipple discharge. Mammogram to look for other lesions, but wont show papilloma. Use galactogram for dx, guide surgical resection

80
Q

Breast abscess

A

Only in lactating women, do i&d, but biopsy abscess wall jic

81
Q

Breast cancer

A

Think it in any woman w/ a palpable breast mass. Also ill-defined fixed mass, orange peel skin, retrac of nipple, eczematoid lesions of areola, reddish orange peel skin over mass, palpable axillary nodes. Trauma does not rule out cancer

82
Q

Breast cancer in pregos

A

Dx same way as if not pregnant, tx same except no rads during preg, and no chemo during first tri. keep baby alive!

83
Q

Mammograms w/ breast cancer show

A

Irregular area of increased density w/ fine microcalcifications that wudn’t there before

84
Q

Treatment of resectable breast cancer

A

Starts w/ lumpectomy + axillary sampling + post-op rads,or modified radical mastectomy. Former only when tumor is small in relatively large breast away from nipple

85
Q

Infiltrating ductal carcinoma

A

standard form! inflamm cancer is only variant that is much worse. Other variants (lobal, medullary mucinous) have slightly better prognosis, tx same way as standard. Lobular might be more bilateral (but not enough to just chop both off)

86
Q

Ductal carcinoma in situ

A

CANNOT mets! But very high incidence of recurrence w/ only local excision, so do total simple masectomy for multicentric lesions, or lumpectomy if its all in one quarter

87
Q

Inoperable cancer of breast

A

Chemo (maybe rads), inoperable based on local extent (not mets)

88
Q

Adjuvant systemic therapy

A

Post surgery in all pts, esp if axillary nodes +. Chemo, or hormonal if receptor positive. premenopausal women get tramoxifen, post menopausal get anastrozole. Frail old women w/ tumors that aren’t too bad should just get hormones!

89
Q

Persistent h/a or back pain in breast cancer pt?

A

METS! Do ct for brain mets, bone scan + x-ray (in pedicles). Radiation + braces

90
Q

Thryoid nodules

A

In euthyroid pts could be cancer (but low incidence so don’t just chop it)
If benign, follow but no intervent
If malignant/indeterminate, do lobectomy, then do frozen section
Total removal if follicular cancers, then tx w/ radioactive iodine later to get the blood-borne mets

91
Q

Thyroid nodules in hyperthyroid pts

A

Almost never cancer, might be hot. Clinical signs = weight loss (but ravenous appetite), palpitations, heat intolerance, moist skin, fidgety, tachycardia, a-fid/flutter, cofirm w/ TSH low or T4 high. Nuke scan shows nodule, tx w/ radioactive iodine or surg the hot adenoma

92
Q

Hyperparathyroidism

A

Serendipitous discovery of high serum calcium! Repeat calc, look for low phosph, rule out bone mets. If persists, do PTH determination (in light of calcium levels). Asx pts get sx at 20%/year, so elective intervention can make sense. Removal = curative, single adenoma

93
Q

Cushing

A

Round, ruddy, hairy face, buffalo hump, fat pads supra clav, obese trunk + abdominal stria, thin weak extremities, osteoporosis, diabetes, HTN, mental instability. W/u w/ low-dose dexameth suppression test. Suppressed at low dose = no disease. If no supression, do 24 hr urine cortisol (if elevated), do high-dose suppression test. If suppressed, high dose pit microadenoma. No suppresion at either dose = adrenal adenoma! Image (MRI pit CT adrenal) and remove. Also a mayo clinic algorithim, look for free urine cortisol and corticotropin levels

94
Q

ZES (gastrinoma)

A

Shows up as virulent peptic ulcer diseases, resistant and too extensive (too many ulcers!) also watery diarrhea. Measure gastrin, look for tumor w/ CT of panc. remove. Also omeprazole for mets disease

95
Q

Insulinoma

A

CNS symptoms b/c of low blood sugar when pt fasting. Ddx is reactive hypoglycemia (after eating) and self-admin of insulin. Plasma assay for disease = high hinsulin and high C, if just insuling, C is low. Do CT of pancreas/locate tumor

96
Q

Nesidioblastosis

A

Devastating hypersecretion of insulin in newborn, needs 95% pancreatectomy (NO!)

97
Q

Glucagonoma

A

Severe migratory necrolytic dermatitis, resistant to therapy, in pt w/ mild diabetes, some anemia, glossitis and stomatitis. Glucagon assay dx, Ct to locate, resect is curative. For inoperable, give somatostatin and streptozocin.

98
Q

Primary hyperaldo

A

Adenoma or hyperplasia. You see: hypoK in HTN female pt NOT on diuretics, some hyperNa, and met ALK. Aldo levels high, renin low. Postural changes (more aldo when upright) suggests hyperplasia, but lack of response is adenoma. Adrenal CT localize, surgical removal

99
Q

Pheochromocytoma

A

Thin, hyperactive women w/ attacks of pounding headache, perspiration, palp, pallor (and extremely high BP). Attacks can subside, not always sustained. start w/u w/ 24 hr urinary determination of VMA or metanephrine (more specific). Follow w/ CT of adrenal glands or radionuke studies if extradrenal chance. Tumors usually big…BE CAREFUL WITH SURGERY…alpha blockers!

100
Q

Coarctation of the aorta

A

Young, htn in arms w/ normal or low or no pressure, CXR shows scalloping of ribs (erosion for large collateral intercostals). Do CT or MRI angio, maybe arteriogram unnecessary. Surgical correction curative

101
Q

Renovascular HTN

A

Two distinct groups- young women w/ fibromuscular dysplacia or old men w/ arteriosclerotic occlusive disease. Either way, HTn resistant to usual meds, and telltale faint bruit over flank or upper abdomen. W/u of scanning + doppler of renal vessels + arteriographic visualization. therapy imperative in yong women (ballon dilatation + stenting) but more controversial in old men!