General Rheummatology Flashcards
What type of joint is each of the following: Ball and socket (eg.?) Intervertebral Pubic symphysis Costochondral Sacroilliac Hinge (eg?)
Synovial Fibrocartilaginous Cartilaginous (fibrocartilaginous?) Cartilaginous Synovial or fibrous??!! Synovial
What are the 3 types of joint?
Fibrous
Fibrocartilaginous
Synovial
What is arthralgia?
Joint pain when joint appears normal on examination
What is arthritis?
Objective evidence of joint inflammation?
3 signs of ‘objective evidence’ of joint inflammation?
Swelling, deformity, effusion
In history taking, what must you always ask about stiffness?
Is there morning stiffness? >30mins in inflamm arthropathies
What is an arthropathy?
Disease of the joint
Synovial joints:
What is an enthesis?
What is epiphyseal bone?
A point at which ligaments and tendons insert into bone
Bone that abuts the joint and is structurally different from the shaft
What is another name for a shaft of bone?
Lol
Metaphysis
What is the role of a synovial joint? How does it achieve this?
To act as a shock absorber and distribute the load over the joint surface
By being a highly compressible structure
Joint capsule:
What is it lined by?
What is it connected to?
Synovium
Periosteum
What is periosteum?
A membrane that covers the outer surface of all bones
Synovial fluid - what is it secreted by and into where?
Synovial cells into the synovial cavity
What is articular cartilage? What is it composed of (3)?
Hyaline cartilage
Water, type II collagen, proteoglycans
What is the difference between a tendon and a ligament?
Tendon - muscle to bone
Ligament - bone to bone
Between which structures is the bursa?
Between the tendon/ligament/muscle and the joint capsule
What is periarticular pain? 3 causes?
Pain from structures surrounding the joint
Enthesitis, bursitis, tendinitis
Pain arising from the joint itself is known as what sort of pain?
Articular pain
What is oligoarthritis?
Arthritis affecting one to four joints during the first six months of disease
What is a common cause of acute, non-traumatic monoarthritis or oligoarthritis in young adults?
Disseminated gonococcal infections
What is the key investigation in acute monoarthritis?
Synovial fluid aspiration with Gr stain and culture and analysis for crystals in gout and pseudogout
What is the most common type of anaemia in musculoskeletal disease?
Normocytic normochromic
Why might you get hypochromic, microcytic anaemia in musculoskeletal disease?
NSAID induced GI bleeding –> iron deficient anaemia
Which factors are positive in seropositive RA?
Rheumatoid factor and anti-CCP antibodies
What does bone scintigraphy localise?
Sites of increased bone turnover and blood circulation
5 examples where bone scintigraphy will see ‘hotspots’?
Osetomyelitis Septic arthritis Post surgery/traua Malignancy Paget's disease
When can ultrasound be used to assess bone density?
At the heel, as a screening procedure prior too DXA (dual energy Xray absorptiometry
When is MRI particularly useful (2)?
Articular disease
Spinal disorders
What does DXA do? Why is it used?
Measures bone mineral density in diagnosis and monitoring of ossteoporosis
When is arthroscopy useful?
Means off visualizing the inside of a joint, espec knee and shoulder.
Biopsy, small surgery, removal of loose bodies