General receptors

Question 1

Major actions of alpha 1 receptors?

Answer 1

increase vascular smooth mm. contraction
increase pup dilator mm contraction
increase intestine/bladder sphincter contract
SYMPATHETIC

Question 2

Major actions of alpha 2 receptors?

Answer 2

decrease sympathetic outflow
decrease insulin release 
decrease lipolysis
increases platelet aggregation
SYMPATHETIC

Question 3

Major action of B1 receptors?

Answer 3

increase
HR, contractility, renin, lipolysis
SYMPATHETIC

Question 4

Major action of B2 receptors?

Answer 4

Vasodilator, bronchodilator
Increase HR, increase contractility,
increase lipolysis, increase insulin

ciliary mm relaxation
SYMPATHETIC

Question 5

Major action of M1 receptors?

Answer 5

CNS, enteric nervous system

PSNS

Question 6

Major action of M2 receptors?

Answer 6

decrease HR
decrease atria contractility
PSNS

Question 7

Major action of M3 receptors?

Answer 7

increase exocrine gland secretion
(lacrimal, salivary, gastric)
increase peristalsis
increase bladder contraction
PSNS

Question 8

M3 receptor effects on bronchioles?

Answer 8

bronchoconstriction

PSNS

Question 9

M3 receptor effects on eye?

Answer 9

increase pupil sphincter contraction (miosis)

ciliary mm contraction (accomodation - near vision)

Question 10

Effects of D1 receptors?

Answer 10

relax renal vascular smooth mm

Question 11

Effects of D2 receptors?

Answer 11

Modulate transmitter release (think BRAIN!)

Question 12

Effects of H1 receptors?

Answer 12

increase nasal and bronchial mucus
increase vascular permeability
contraction of bronchioles, puritis, pain

Question 13

Effects of H2 receptors?

Answer 13

increases gastric acid secretion

Question 14

Which receptors work via Gq and increase [Ca]?

Answer 14

H1
a1
V1
M1, M3
"HAVE1 M&M"

Question 15

Which receptors work via cAMP?

Answer 15

“MAD 2’s”
M2
Alpha 2
D2

Question 16

Presynaptic PSNS nerve releases what at terminal?

Answer 16

ACH!

Question 17

Post synaptic PSNS receptors are ____ ?

Answer 17

nicotinic

Question 18

Preganglionic sympathetics release _____ ?

Answer 18

ACh

Question 19

Post ganglionic sympathetics release what at sweat gland synapses?

Answer 19

Ach

Question 20

Post ganglionic sympathetics release ____ onto ___ and ___ receptors at the nerve ending?

Answer 20

NE onto alpha and beta receptors

think cardiac, smooth mm, gland cells, nerve term

Question 21

Where is Dopamine released post synaptically?

Answer 21

sympathetic nerve terminals in
renal vasculature
smooth muscle

Question 22

Nicotinic ACh receptors are all ________.

Answer 22

Ligand gated!

Question 23

Muscarinic Ach receptors are _______ that act through ______.

Answer 23

Muscarinic Ach receptors are GPCRs that act through 2nd messengers.