General Psychopharmacology Flashcards
Why are we careful in perinatal psychiatry?
there are two patients (baby and mom)
What do you base treatment decisions on?
- based on a risk/benefit analysis
- made on a case by case basis
Is there a single best treatment for all patients?
NO! there is no single best or safest medication for use during pregnancy and the postpartum period
Is there one single study about perinatal psychiatry?
no, it is a conglomerate of studies so you need to read papers
What are the risks of untreated mental illness in pregnancy?
-preterm birth
-low birth weight
-pre-eclampsia
-impact on bonding and attachment
-self medicating with substances/alcohol
-overdose/suicide
***According to CDC, how many maternal deaths are preventable?
***80%
According to CDC, what is the number one cause of maternal death?
mental health (substance use and suicide)
What are the 6 most frequent underlying causes of pregnancy-related deaths?
- mental health conditions 22.7%
- hemorrhage 13.7%
- cardiac and coronary conditions 12.8%
- infection 9.2%
- thrombotic embolism 8.7%
- cardiomyopathy 8.5%
Mental health conditions are the leading underlying cause for maternal death in which groups?
-hispanic women
-non-hispanic white women
Pregnant women’s distress can cause what changes in fetus?
-epigenetic changes in placental genes are seen
-mildly increased DNA methylation of glucocorticoid related genes
Elevated in utero exposure to cortisol is associated with what changes in brain behavior development?
-increased emotionality
-impaired learning and motor development
The negative effect of chronic maternal depression on child social outcomes is related to genetic and peripheral biomarkers in ______ system.
oxytocin