General Psychopharmacology Flashcards

1
Q

Why are we careful in perinatal psychiatry?

A

there are two patients (baby and mom)

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2
Q

What do you base treatment decisions on?

A
  1. based on a risk/benefit analysis
  2. made on a case by case basis
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3
Q

Is there a single best treatment for all patients?

A

NO! there is no single best or safest medication for use during pregnancy and the postpartum period

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4
Q

Is there one single study about perinatal psychiatry?

A

no, it is a conglomerate of studies so you need to read papers

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5
Q

What are the risks of untreated mental illness in pregnancy?

A

-preterm birth
-low birth weight
-pre-eclampsia
-impact on bonding and attachment
-self medicating with substances/alcohol
-overdose/suicide

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6
Q

***According to CDC, how many maternal deaths are preventable?

A

***80%

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7
Q

According to CDC, what is the number one cause of maternal death?

A

mental health (substance use and suicide)

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8
Q

What are the 6 most frequent underlying causes of pregnancy-related deaths?

A
  1. mental health conditions 22.7%
  2. hemorrhage 13.7%
  3. cardiac and coronary conditions 12.8%
  4. infection 9.2%
  5. thrombotic embolism 8.7%
  6. cardiomyopathy 8.5%
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9
Q

Mental health conditions are the leading underlying cause for maternal death in which groups?

A

-hispanic women
-non-hispanic white women

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10
Q

Pregnant women’s distress can cause what changes in fetus?

A

-epigenetic changes in placental genes are seen
-mildly increased DNA methylation of glucocorticoid related genes

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11
Q

Elevated in utero exposure to cortisol is associated with what changes in brain behavior development?

A

-increased emotionality
-impaired learning and motor development

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12
Q

The negative effect of chronic maternal depression on child social outcomes is related to genetic and peripheral biomarkers in ______ system.

A

oxytocin

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