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cephalosporins > general properties > Flashcards

general properties Flashcards

1
Q

MOA

A

similar to penicillin

bacteriocidal

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2
Q

toxicities

A 
PAD
1- pain at site of inj.
IM --- severe pain
IV --- thrombophlebitis
2- prothrombin def.
3- anaphylaxis
4- allergy ( hypersensitivity ) - penicillin similar
5- disulfiram like rx
6- diarrhea
7- renal toxicity
8- super inf.
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3
Q

with aminoglycosides

A

inc. nephrotoxicity

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4
Q

penicillin

A

cross sensitivity

Steven Johnson syndrome

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5
Q

ineffective against

A

MRSA
L. monocytogenes
c. dificile
enterococci

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6
Q

nucleus

A

7-aminocephalosporanic acid

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7
Q

rings

A

b-lactam

dihydrothiazine ring

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cephalosporins (6 decks)

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