General Physiology Exam I Flashcards

1
Q

Anatomy

A

What does it look like? Form.

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2
Q

Physiology

A

How doe it work? Function.

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3
Q

Homeostasis

A

maintenance of internal environment

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4
Q

Control Theory

A

a control center senses when a physiological condition is out of balance and stimulates an effector organ to return the condition to the normal, optimal level

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5
Q

Acute response

A

temporary, immediate physiological adjustment; ex: movement, inflammation, cell stress response, adjust ventilation/heart rate

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6
Q

Acclimatization

A

plasticity; reversible physiological adjustment over several days; chainge in gene expression, not sequence; ex: adjust makeup of cell membrane, adjust metabolic rate, adjust lung capacity, tanning

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7
Q

Adaptation

A

permanent physiological adjustments over evolutionary time; only occurs between generations; non-reversable; present in DNA sequence

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8
Q

Acclimatization vs Adaptation

A

can share mechanisms; acclimation can maintain a species long enough for genetic adaptation to occur

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9
Q

nucleus

A

contains genetic material (DNA)

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10
Q

endoplasmic reticulum

A

protein and lipid synthesis

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11
Q

golgi complex

A

modification, sorting, and packaging of ER products

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12
Q

vesicles

A

intracellular transport

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13
Q

lysosomes

A

intracellular digestion

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14
Q

mitochondria

A

oxidative phosphorylation (ATP synthesis)

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15
Q

cytosol

A

glycolysis, protein synthesis

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16
Q

genes

A

unit of expression of DNA

17
Q

gene expression

A

the process of turning DNA into a protein (transcription and translation)

18
Q

exons

A

gene consisting of coding sequences

19
Q

introns

A

non-coding sequences

20
Q

golgi cis and trans

A

the cis face is where synthesized proteins and lipids pinch off from the ER and are transported to the golgi complex; modification of ER products includes post-translational modifications of proteins which are then pinched off from the trans face to other organelles or the plasma membrane.

21
Q

regulation of gene expression

A
  1. regulation of transcription; 2. RNA modification; 3. mRNA export; 4. mRNA degredation; 5. translation; 6. modification and sorting; 7. protein degredation; 8. protein activation state
22
Q

Michaelis-Menton Kinetics

A

velocity of the reation is proportional to substrate concentration

23
Q

Michaelis constant (Km)

A

a measure of enzyme substrate affinity; Km is substrate concentration at 1/2 Vmax

24
Q

enzyme flux

A

overall rate of reaction in a pathway