General Pharmacomogy Flashcards

1
Q

What are pro drugs?
4 points

A

Prodrug is a pharmacologically inactive derivative of an active drug and undergoes in vivo biotransformation to release the active drug by chemical or enzymatic contact

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2
Q

What is bioavailability
3 things

A

is the fraction of an administered drug that reaches the systemic circulation following absorption

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3
Q

What is an agonist
3 points

A

substance that mimics the actions of a neurotransmitter or hormone to produce a response when it binds to a specific receptor

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4
Q

What’s an antagonist?

A

a substance that stops the action or effect of another substance. For example, a drug that blocks the stimulating effect of estrogen on a tumor cell is called an estrogen receptor antagonist.

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5
Q

What is pharmacokinetics?

A

It is the study of process by which a drug is absorbed, distributed, metabolized & eliminated by the body. this process involves its passage across cell
membranes. ADME

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6
Q

What is pharmacodynamics the study of on the body (3 things)?

A

the study of the biochemical, physiological and molecular effects of drugs on the body and involves receptor binding

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7
Q

What’s an enzyme?
What is it almost always?
4 words

A

biological catalyst

speeds up rate of a specific chemical reaction in the cell. The enzyme is not destroyed during the reaction and is used over and over.

Almost always a protein

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8
Q

What does congestive heart failure mean and what would this produce

A

Both left and right sided
Pulmonary congestion and peripheral oedema

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