General Pharmacomogy Flashcards
What are pro drugs?
4 points
Prodrug is a pharmacologically inactive derivative of an active drug and undergoes in vivo biotransformation to release the active drug by chemical or enzymatic contact
What is bioavailability
3 things
is the fraction of an administered drug that reaches the systemic circulation following absorption
What is an agonist
3 points
substance that mimics the actions of a neurotransmitter or hormone to produce a response when it binds to a specific receptor
What’s an antagonist?
a substance that stops the action or effect of another substance. For example, a drug that blocks the stimulating effect of estrogen on a tumor cell is called an estrogen receptor antagonist.
What is pharmacokinetics?
It is the study of process by which a drug is absorbed, distributed, metabolized & eliminated by the body. this process involves its passage across cell
membranes. ADME
What is pharmacodynamics the study of on the body (3 things)?
the study of the biochemical, physiological and molecular effects of drugs on the body and involves receptor binding
What’s an enzyme?
What is it almost always?
4 words
biological catalyst
speeds up rate of a specific chemical reaction in the cell. The enzyme is not destroyed during the reaction and is used over and over.
Almost always a protein
What does congestive heart failure mean and what would this produce
Both left and right sided
Pulmonary congestion and peripheral oedema