General Pharmacology Flashcards

1
Q

What is the definition of pharmacology?

A

The study of drugs and their interactions with living organisms.

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2
Q

True or False: Pharmacodynamics is the study of how the body affects a drug.

A

False. Pharmacodynamics is the study of how a drug affects the body.

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3
Q

What is the term for the study of drug absorption, distribution, metabolism, and excretion?

A

Pharmacokinetics.

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4
Q

Which type of drug administration route bypasses the gastrointestinal tract?

A

Parenteral administration.

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5
Q

What is the term for the maximum effect a drug can produce regardless of the dose?

A

Efficacy.

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6
Q

Which term describes the ratio of a drug’s toxic dose to its therapeutic dose?

A

Therapeutic index.

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7
Q

What is the name for a drug that binds to a receptor and causes a biological response?

A

Agonist.

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8
Q

True or False: Antagonists bind to receptors and activate them.

A

False. Antagonists bind to receptors but do not activate them.

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9
Q

What is the term for the study of drug interactions within a living organism?

A

Pharmacodynamics.

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10
Q

Which type of drug administration route involves oral ingestion?

A

Enteral administration.

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11
Q

What is the term for the process of a drug moving from its site of administration into the bloodstream?

A

Absorption.

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12
Q

Which phase of drug metabolism involves the modification of a drug to make it more water-soluble?

A

Phase II metabolism.

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13
Q

True or False: The half-life of a drug is the time it takes for the drug to reach peak plasma concentration.

A

False. The half-life is the time it takes for the drug concentration in the body to decrease by half.

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14
Q

What is the term for the proportion of a drug that reaches systemic circulation unchanged?

A

Bioavailability.

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15
Q

Which term describes the process by which a drug is eliminated from the body?

A

Excretion.

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16
Q

What is the name for a drug that binds to a receptor but does not activate it, blocking the receptor from other molecules?

A

Antagonist.

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17
Q

True or False: The volume of distribution of a drug is a measure of how extensively a drug is distributed in the body.

A

True.

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18
Q

What is the term for the study of how drugs are absorbed, distributed, metabolized, and excreted in individuals?

A

Clinical pharmacokinetics.

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19
Q

Which type of drug administration route involves injection into the muscle?

A

Intramuscular administration.

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20
Q

What is the term for the process of a drug being transported from the bloodstream to the tissues and organs?

A

Distribution.

21
Q

Which phase of drug metabolism involves the modification of a drug to make it more hydrophilic?

A

Phase I metabolism.

22
Q

True or False: The elimination half-life of a drug is the time it takes for the drug to be completely removed from the body.

A

False. The elimination half-life is the time it takes for the drug concentration in the body to decrease by half during the elimination phase.

23
Q

What is the term for the process of a drug being metabolized by enzymes in the liver before reaching systemic circulation?

A

First-pass metabolism.

24
Q

Which term describes the study of how a drug affects individuals based on genetic differences?

A

Pharmacogenetics.

25
True or False: The bioavailability of a drug is 100% when administered intravenously.
True.
26
What is the term for the study of the effects of drugs on populations?
Pharmacovigilance.
27
Which type of drug administration route involves injection directly into the bloodstream?
Intravenous administration.
28
What is the term for the study of drug concentration and response relationships in patients?
Clinical pharmacodynamics.
29
Which phase of drug metabolism involves the conjugation of a drug with endogenous molecules?
Phase II metabolism.
30
True or False: Drug metabolism primarily occurs in the kidneys.
False. Drug metabolism primarily occurs in the liver.
31
What is the term for the process of a drug being broken down into metabolites that are more easily eliminated from the body?
Metabolism.
32
Which term describes the study of how a drug's effects vary based on the dose administered?
Pharmacodynamics.
33
True or False: Drug distribution is the process of a drug moving from the bloodstream to the site of action.
True.
34
What is the term for the time it takes for a drug to reach peak plasma concentration after administration?
Time to peak concentration.
35
Which type of drug administration route involves inhalation of a drug?
Pulmonary administration.
36
What is the term for the process of a drug being removed from the body through urine or feces?
Elimination.
37
Which phase of drug metabolism involves the oxidation, reduction, or hydrolysis of a drug?
Phase I metabolism.
38
True or False: Drug excretion primarily occurs through the lungs.
False. Drug excretion primarily occurs through the kidneys.
39
What is the term for the study of how a drug's concentration in the body changes over time?
Pharmacokinetics.
40
Which term describes the study of how a drug affects individuals based on environmental factors?
Pharmacogenomics.
41
True or False: Drug absorption is the process of a drug being transported from the bloodstream to the tissues and organs.
False. Drug distribution is the process of a drug being transported from the bloodstream to the tissues and organs.
42
What is the term for the study of how drugs interact with each other in the body?
Drug-drug interactions.
43
Which type of drug administration route involves applying a drug to the skin?
Topical administration.
44
What is the term for the process of a drug binding to a receptor and preventing other molecules from binding?
Competitive antagonism.
45
Which phase of drug metabolism involves the conjugation of a drug with endogenous molecules or metabolites?
Phase II metabolism.
46
True or False: Drug metabolism primarily occurs in the gastrointestinal tract.
False. Drug metabolism primarily occurs in the liver.
47
What is the term for the process of a drug being converted into a more polar compound to facilitate excretion?
Biotransformation.
48
Which term describes the study of how a drug's effects vary based on the individual's age and sex?
Pharmacogenomics.