General Pharmacology Flashcards
1
Q
Enzyme inhibitors
A
Vit- Valproate K -ketoconazole Can't- Cimetidine Cause -Ciprofloxacin Enzyme- Erythromycin Inhibition- Isoniazid
2
Q
Enzyme inducers
A
G-riseofulvin P-henytoin R-ifampicin S-moking Cell - Carbamazepine Phone -phenobarbitone
3
Q
Cytochrome P 450 inhibitors
A
I-soniazid Am At- allopurinol Cafe-cimetidine Coffee- chloramphenicol Day-disulfiram
4
Q
Drugs with low therapeutic index
A
Warning-warfarin These-theophylline Drugs-digoxin Are-antiepileptics Lethal-lithium
5
Q
Zero order kinetic drugs
A
zero Warfarin Alcohol, aspirin T-theophylline T-tolbutamide Power-phenytoin
6
Q
Acidic drugs
A
Weak -warfarin A-ntiepileptic C-hlorothiazide I-buprofen and aspirin D-opamine prodrug(levodopa)
7
Q
Drug absorption increased by fatty food
A
P-osaconazole L-umefantrine A-lbendazole and atovaquone Gu-griseofulvin E-favirenz
8
Q
Drugs can’t be dialysed
A
B-eta blocker, Benzodiazepine A-mphetamine D-igoxin D O-pioids , organophosphates C-cb's , chloroquine
9
Q
Druge metabolised by acetylation
A
Singer-sulfonamide D-apsone I-soniazid N-itrazepam C-lonazepam H-ydralazine A-mantadine, amrinone, acebutalol K-caffeine Pooja- procainamide, phenelzine
10
Q
Hit and run drugs
A
M-AO inhibitors
O-meprazole
R-eserpine
Gue- guanethidine
11
Q
PgP inhibitors
A
V-erapamil A-miodarone C-yclosporine I-traconazole N-ifedipine E-rythromycin
12
Q
Alpha beta adrenergic receptors function
A
A. Constriction of bv
B. Dilatation of bv , contract heart
13
Q
Opioid (meow) receptor action
A
S-edation C-onstipation A-nalgesic R-espiratory depression E-uphoria D-ependency
14
Q
Beta agonist side effects
A
T-achycardia
T-remors
T-olerance
15
Q
Anticholinergic effects
A
Can’t spit
Can’t shit
Can’t see
Can’t pee
16
Q
MAO inhibitors
A
H-ypertension
H-epatocellular jaundice
H-yperthermia
17
Q
Atropine side effects
A
Hot as a hare Red as a beet Dry as a bone Mad as a hatter Full as a flask Blind as a bat
18
Q
SSRI side effects
A
S-exual dysfunction
S-erotonin syndrome
S-tomach upset
