General Paeds Flashcards
Neonate fluid requirements
Day 1
Day 5
Neonate fluid requirements
Day 1 - 50ml/kg/day
Day 5 - 150ml/kg/day
Paeds Fluid requirements
ml/kg/day
Paeds Fluid requirements
> 10kg - 100ml/kg/day
20kg - 50ml/kg/day
<20kg - 20ml/kg/day
Paeds Fluid requirements
5 kg child
15 kg child
25 kg child
50kg child
Paeds fluid requirements
5 kg child
= 500ml (5 x 100)
15 kg child
= 1250ml (10 x 100 + 5 x 50)
25 kg child
= 1600ml
[(10 x 100) + (10 x 50) + (5 x 20)]
50 kg child
= 2100ml
[(10 x 100) + (10 x 50) + (30 x 20)]
Working weight
- Measurement
Working weight
- Birthweight
- Until Current Weight exceeds
Neonatal disease
- 3 Aetiologies
Neonatal diseases
- Congenital
- Infectious
- Nutritional
Neonatal jaundice
- Prevalence
- Physiology
Neonatal jaundice
- Prevalence
- 60% term
- 80% pre-term - Physiology
- Excess bilirubin (RBCs)
- Immature liver
Neonatal Jaundice
- Pathological aetiologies and causes
Neonatal jaundice
- Pathologies
- Increased RCB breakdown
- Extensive bruising
- Cephalohaematoma - Haemolytic disease
- Rhesus, ABO
- G6PD
- Spherocytosis - Dehydration
- Unwell
- Infection - Prolonged
- Infection
- Metabolic
(hypothyroid, pituitarism, galactosaemia)
- Breast milk
- GI
(Biliary atresia, choledochal cyst)
Physiological jaundice
- Natural History
Natural jaundice history
- Starts d2-3
- Peaks d5
- Resolves d10
- Self limiting
Jaundice
- Presentation
Jaundice presentation
- Colour
- Drowsy
- Short feeds
- Tone/seizures
- Unwell (infection, uring output, abdo sign, black stool)
Jaundice
- Ix
Jaundice Ix
- TCB
>35/40wk
> 24 hrs
<250 micromol - SBR
<35/40wk
<24 hrs
TCB >250micromol - Baby (and mother)
- Blood group
- DCT (direct Coombs)
- FBC
Jaundice
- Tx
Jaundice Tx
- Phototherapy
- NICE Threshold Graph
- Eye protection
- Check for rebound hyperbilirubinaemia
- EBM preferred, no additional fluid - Exchange transfusion
- Encephalopathy
- ICU
- Umbilical line (V or A) - IVIG
- Haemolytic disease
(rhesus/ABO)
- Adjunct to phototherapy
Neonatal Jaundice
- Complications
Kernicterus from Jaundice
- Brain dysfunction
- Irreversible grey-matter damage
Perinatal History
- 7 Steps
Perinatal History
- Anti-natal history
- All scans ok - Mode of delivery
- Why c? - Gestation
- Term? - Birth weight
- Resus?
- Admission?
- NNU, SCBU, PNW - When first BO/PU?
Paeds History
- Feeding
Paeds Feeding Hx
- Enteral vs PN
- Breast/bottle
- EBM - Quality/Regularity/Frequency
eg. 150mlg/kg/day til weaned - When weaned?
- Eating now?
- 1Y -> Home food
Child Imms
- Timings
Child Imms Timings
2mo (Six in one, MenB, Rotavirus)
3mo (6in1, PCV (Pneumo conj), Rota)
4mo (Six in 1, MenB)
1yr (Hib/MenC, PCV, MMR, MenB boost)
3-5yr (DTap/IPV, MMR)
Developmental Timeline
8 Weeks - 5 years
Developmental timeline
8 weeks - Embryogenesis
3-9 months - Fetus
22 weeks - 7 days - Perinatal
0-28 days - Neonate
1mo-1 year - Infant
1 year - 3 years - Toddler
3-5 years - Pre-school
Three Trisomies
Trisomy conditions
- Trisomy 13 (Patau)
- 1/15,000
- 80% CHD
- Holoprosencephaly
- Cleft lip and palate
- Microphthalmia / anophthalmia
- Hypotelorism/cyclops
- Trisomy 18 (Edward’s)
- 1/6,000LBs
- 8% 1Y survival
- 90% CHD
- GI/GU abnormaliites
- Neurological abnormalities
- Micrognathia (small jaw)
- Small facial features/head
- Cleft lip/palate
- Overriding fingers
- Trisomy 21 (Down)
- 1/691
- 50% CHD (AVS 31%+)
- 5% GI obstruction
- Brachycephaly with flat occiput
- Epicanthal folds
- Uplsanting palpebral fissure
- Low nasal bridge, low-set ears
Aneuploidies
- Sex chromosome
Aneuploidies
- 45, X0 (Turner)
- 1/2500 (detected at puberty)
- Intelligence normal
- CHD, IHD, DM, OP
- 47, XXY (Klinefelter)
- 1/660
- Tall
- Hypogonadism
- Sparse hair
- Gynaecomastia
- Minor LDs
- 47, XYY (Jacob’s)
- 1/1000
- No symptoms
- Tall
- Low muscle
- ASD/LD
- 47 XXX (Trisomy X)
- 1/1000
- No symptoms
- Tall
- Curved little finger
- Epicanthal fold
- Flat feet
- Mosaicism
- 45, X/ 46, XX
- 45, X/ 46, XY
Nephrotic syndrome
- S&S
- Ix
- Mx
Nephrotic syndrome
- Triad
- Oedema
- Proteinuria
- Hypoalbuminaemia - Ix
- Varicella IgG - Mx
- Steroid (60mg/m2)
- Oral pred 4/7
- Home urine dip
- Steroid dependence management
Post-strep GN
- S&S
- Mx
Post-strep GN
- S&S
- HTN
- Haematuria
- Low C3 complement
- High ASOT (Antistreptolysin O titre) - Mx
- Furosemide
Nephritis
- Causes
Nephritis causes
- Post-infective GN
- IgA vasculitis
- HSP/Henoch-Schonlein Purpura - SLE
- MPGN II
- Membranoproliferative - Vasculitis (ANCA)
- Anti-GBM
Safeguarding
- Children’s Acts
Children’s Acts
1989 Children’s Act
- Needs of the Child are paramount
2004 Children’s Act
- Statutory Duty
Working together to safeguard children
- Aims
- Years
Working together to safeguard children
- Aims
1. Keep all safe from harm
2. Inter-professional working - Years
1. 2006
2. 2010. 2014, 2018
3. 2021
Lord Laming Reports
- Focuses
Lord Laming Reports
- 2003 - Victoria Climbié
- 2009 - Baby Peter Connelly
Safeguarding
- When can a baby roll?
Safeguarding
- Back to front 4-5 months
- Front to back 6-8 months
Safeguarding
- Bruising
Safeguarding
- I can’t move so I can’t bruise
- Ear injuries are non-accidental
Under-2 Investigation
- Protocol
Under-2 investigation protocol
- Skeletal survey (27 films)
- CT Head
- Ophthalmology
- Clotting screen
Accidental bruising
- Locations
Accidental bruising
- Bony prominences (93%)
- Front sided
- Knees
- Shins
Birthmarks
Birthmarks
- Grey slate nevus
1. 0-4 yo
2. Buttocks, upper leg, Lower back
Salmon patches
1. 0-2yo
2. Eyelids, head, neck
Haemangioma/strawberry
1. 0-7yo
2. Blood vessels, maybe blue
Port wine stains
1. From birth
2. Face/neck
Cafe-au-lait
1. Common dark patches
2. Anywhere
Congenital mole
1. Cancer risk if large
2. Pigment overgrowth
Child development
- Four elements
Child development elements
- Gross motor
- Fine motor and visual
- Speech and hearing
- Social
Development milestones
- Gross motor 6wks - 6mo
Gross motor milestones
6wks
- Turn head to both sides
- Lifts head on belly
- Head lag with pull to sit
- Kicking legs and moving arms on back
3-4mo
- No head lag when pulled to sit
- Pushes up on forearms on belly
- Rolls from belly to back
5-6mo
- Rolls from back to belly
- Brings feet to mouth on back
Development milestones
- Gross motor 6-12 mo
Gross motor 6-12mo
6-8 mo
- Sits alone
- Reaches for toys
- Crawls on belly
9-11mo
- Crawls on hands and knees
- Pulls to standing
- Cruises
- Walks with hands held
11-12-mo
- Walks with one hand held
- Stands along for a few seconds
Development milestones
- Gross motor 12-24mo
Gross motor 12-24 mo
13-14 mo
- Crawls up stairs
- Stands from floor
- Walks alone
15-18 mo
- Kick a ball
- Run with falling
- Stairs with help
24 mo
- Walks and runs fairly well
- Jumps with both feet
- Stairs alone
- Kicks with either foot
Baby Development
- Reflexes
Reflex disappearing
2 mo - Stepping, Moro
3mo - Rooting
5-6mo - Palmar grasp, sucking
5-7mo - Tonic neck/fencing
9-12 - Plantar grasp
Speech and hearing
- Screen
- Development
Speech and hearing
- Day 1/day 2 screening hearing
- 3mo making sounds
Tonsillectomy
- Criteria
- Post-op
Tonsillectomy
- Criteria
4 x 3 years
5 x 2 years
7 x 1 year - Post-op
1. Food and fluids
2. Sats Monitoring
Neonatal Thrombocytopenia levels
1. Normal
2. For procedure
3. For transfusion
Neonatal Thrombocytopenia
150 - Normal
75 - For procedure
50 - For transfusion
NAS
- S&S
- Management
Neonatal abstinence syndrome
- S&S
1. Continuous cry
- Tachypnoea
- Restlessness
- Scratching
- Tremor
- Hypertonia
- Difficulty feeding
- D/V
- Fever
- Convulsions
Mx
1. HepB Vaccine
2. Lipsitz score
3. Oral morphine
4. Phenobarbital
Fontanelles
- Five bones of cranium
Cranium
- Frontals
- Parietals
- Occipital
Anterior fontanelle
- Borders
Anterior fontanelle
- L/R Frontal
- Metopic suture - L/R Parietal
- Sagital suture
- Coronal suture
Fontanelles
- Closure timeline
Fontanelle closure
- Intramembranous ossification
- Anterior
- 13-24 months
- Males before females - Posterior
- 6-8 weeks
Fontanelle associations
- Large
- Delayed closure
Large fontanelle conditions
- T21
- Achondroplasia
- Congenital hypothyroidism
- Rickets
5.Raised ICP
Neonate
- Dehydration signs
Neonatal dehydration
- Sunken fontanelle
- Dry membranes
- Sunken eyes
- Poor tears
- Peripheral perfusion
- Dry diapers
Bulging anterior fontanelle
- Conditions
Bulging a. fontanelle
- Raised ICP
- Hydrocephalus
- Hypoxemia
- Meningitis
- Trauma
- Haemorrhage
Posterior fontanelle
- Borders
Posterior fontanelle
- Parietal lobes
- Occipital lobe
- Lambdoid suture
Posterior fontanelle
- Delayed closure
Open p. fontanelle
- 8+weeks
- Hydrocephalus
- Hypothyroid
Mastoid fontanelle
- Borders
- Closure
Mastoid fontanelle (x2)
- Anterolateral
- Borders
- Parietal
- Temporal
- Occipital
- Closure
1. 6-18 months
Sphenoid fontanelle
- Borders
- Closure
Sphenoid fontanelles (x2)
Borders
1. Frontal
2. Parietal
3. Temporal
4. Sphenoid
Closure
- 6 months
Third fontanelle
- Epidemiology
Third fontanelle
- 6%
- Associations
- T21
- Rubella
B symptoms
- Origin
- Examples
Symptoms
- Origin
1. Ann Arbour Grading
2. Lymphoma - B Symptoms
1. Fever
2. Night sweats
3. Weight loss (10%/6mo)
Haemolysis
- Causes
Haemolysis DDx
- Autoimmune
- Cold agglutinin-mediated (IgM)
(M. pneumonia/EBV/mumps/CMG)
- Warm agglutinin-mediated (IgG)
(HIV, Hep C, Mono)
- Paroxysmal cold haemoglobinuria (IgG)
(URTI, chickenpox, mono) - Infectious
- Malaria
- C. perfringens - Haematological
- MAHA
(TTP, HUS, DIC) - Congenital
Haemolysis
- Ix
Haemolysis Ix
- Reticulocytes
- Low = Anaemic - Smear
- Schistocytes = destruction - (+)LDH and (-)Haptoglobin
- Destruction/haemolysis - INR, PT, aPPT, fibrinogen
- Affected by DIC, not HUS/TTP
Paeds
- General examination
Paeds general exam
- Demographic
- Succinct development
- eg. GM normal for age - HPC
Eg. RDS
- SVIA/HFNC
- Good cry
- Intra/subcostal recessions
- Grunting/Tracheal tug/Nasal flare
Febrile Seizure
- Pres
- Mx
Febrile Seizure
- Pres
1. 6mo-5yo
2. 38º
3. Male
4. 3-5 min seizure, rapid recovery - Mx
1. CBG
2. R/O Meningitis/Encephalitis - ?LP
3. Electrolytes if vomiting/ketotic - Ca, P, Mg
- Fever management
- Para/Ibu - Status management
- Midazolam
- Phenytoin
Floppy Baby
- Pres
- Aetiologies
Hypotonia
- Pres
1. Transient in newborn - Not severe
2. Profound/persistent - Causes
- Acutely unwell child
- Central
- Chromosomal/Genetic - Spinal
- Cord Injury/Ischaemia
- SMA (spinal muscular atrophy) - Polyneuropathies
- NMJ
- Transitory myasthenia
- Familial infantile myasthenia - Myopathy
- Muscular dystrophies
- Myotonic dystrophies
Floppy Baby
- Ix
- Mx
Hypotonic infant
- Ix
- HF exam
- Organomegaly
- Temperature/septic screen
- AVPU
- HIE assessment
- Genetic testing
- Mx
- Bedside
- Airway management
- Resp and feeding support
- VBG
- Hx and Ex - Bloods
- FBC, U&E, Glucose, Electrolytes, TFTs
- CRP + Culture
- CSF - Imaging
- USS - Special tests
- Urine AAs
- Urine GAGs
- EEG
Childhood gait
- Ten Differentials
Childhood gait DDx
- NAI
- <12mo
- Inconsistent - Toddler’s fracture
- Spiral tibia - Septic arthritis
- <10yo (3-7)
- Sudden-onset hip
- Fever - DDH
- 12-24mo
- First-born breech females
- Barlow’s/Ortolani’s - Perthes
- 4-10yo
- Weeks/days - Osgood-Schlatter
- Older child after activity
- Active growth - JIA
- Oligo (pre-school, girls)
- Poly (older,girls) - SCFE
- 11-15yo, boys
- obesity, hypothyroid, delayed 2º sexual - CP
- Muscular distrophies
- Boys, delayed walking
- Family history
Muscular dystrophies
- Epidemiology
- Pathophysiology
Muscular dystrophies
- Epidemiology
1. DMD most common - 1/3000 male births
- 2/3 x-linked
2. Becker MD - 1/25,000
- Pathophysiology
1. Dystrophin protein deficiency
2. Muscle fibre necrosis
3. Rapidly progressive dystrophy- More common than hypotonia at birth
- Delayed motor milestones
Muscular dystrophies
- Staging
- Mx
Muscular Dystrophies
Stage 1 - Ambulatory
1 Psychological support
2 PT
- Muscles
- Contractures (CSTs, surgery)
3 Glucocorticoid therapy
- Muscle strength and function
Stage 2 - Non-ambulant
1 ADLs
- Vehicles
- Computers
2 Nutrition
- Swallow (PEG/RIG)
- Tachypnoea
3 Scoliosis prevention
Stage 3 - Ventilator-supported
1 Muscle rest
- IPPV
- MAC (mechanically-assisted-coughing)
- Support
Paediatric oedema
- 10 General Causes
Generalised paeds oedema
- Nephrotic
- CKD
- CHD
- Protein-losing enteropathy
- CF
- Malnutrition
- Refeeding
- Water overload
- SIADH
- Hypothyroid
Paediatric oedema
- 10 Localised causes
Localised paeds oedema
- Infections/bites
- Trauma
- Henoch-Schonlein P (HSP)
- Graves’
- Juvenile dermatomyositis
- Venous obstruction
- PD
- Lymphoedema