General on Viruses Flashcards
1
Q
Circo
A
- ssDNA, circular
- Icosohedral, No envelope
- infects dividing cells
- replicates in the nucleus
- resistent to the environment
2
Q
Adeno
A
- dsDNA, linear
- icosohedral
- encodes it’s on DNA polymerase and factors regulating cell processes
- has a fibre and penton to bind to cell surface
- highly immunogenic
- causes RBC to clump: inhibited by a specific AB: HAI test
3
Q
Herpes
A
- dsDNA, linear
- icosohedral, envelope with glycoproteins
- monocistronic genome
- a,b,g subclasses
- latency properties
4
Q
Papilloma
A
- dsDNA, circular
- Icosohedral (with 72 star shaped capsomers)
- L1 and L2 proteins
5
Q
Asfar/pox
A
- dsDNA, linear
- has an envelope
- replicates in the cytoplasm
- vector mediated
6
Q
Parvo
A
- ssRNA, linear
- Icosohedral
- infects and kills dividing cells
- persists in environment
- crosses placenta
7
Q
Retro
A
- dsRNA
- lipid envelope
- reverse transcriptase
- persistent infections
- long incubation periods
- susceptible to dessication
8
Q
Pico
A
- ssRNA +ve sense
- Icosohedral
- replicates in cytoplasm
- +ve sense can act as mRNA
- encodes it’s own viral polymerase
9
Q
Calci
A
- ssRNA +ve sense
- Icosohedral
- single capsid protein (star of david)
- 2/3 reading frames
10
Q
Birna/Reo
A
- dsRNA linear
- Icosohedral
- replicates in cytoplasm
- viral polymerase
11
Q
Corona
A
- ssRNA +ve sense
- mutates frequently
12
Q
Arteri
A
grows in macrophages/endothelial cells
13
Q
Orthomyxo
A
- segmented RNA
- envelope with HA/NA glycoproteins
- encodes own viral polymerase
14
Q
Paramyxo
A
- ssRNA -ve sense
- helical, enveloped
- replicates in cytoplasm
15
Q
Rhabdo
A
- ssRNA -ve sense
- Helical, enveloped
- bullet shaped