General OB Anesthesia Flashcards
Respiratory effects of pregnancy and anesthetic
- Swelling of nasal and oral
- Increases in MV, TV, VO2, Not RR (returns 6 wks PP)
- PaCO2 to 30 by week 12, pH to 7.44 with metabolic compensation
- Decrease in FRC (returns by 2 weeks PP)
- Use smaller ETT, possible difficult intubation
- Preoxygenate 3-5 min or 4 VC breaths (reduced FRC and increased VO2)
- MAC decreased 40%
CV effects of pregnancy
- Increased CO (highest immediately PP)
- Increased SV, HR
- Decreased SVR, DBP
- No change in BP
- Aortocaval compression (left uterine displacement)
GI effects of pregnancy
- Decreased motility during labor
- Decreased LES tone
- Increased aspiration risk
Hematologic effects of pregnancy
- Increased fluid volume, plasma volume, RBC volume
- Anemia of pregnancy (11 g/dL)
- Increased coagulation factors with shortened PT and PTT
Labs for healthy cesarean
- CBC with platelets
- Type and cross with 4 units (if increased risk of bleeding)
Preoperative medications for healthy cesarean
- Nonparticulate antacid Sodium citrate 30 minutes prior to anesthesia (goal pH > 2.5)
- IV H2 antagonist (ranitidine)
- Fasting guidelines as per non-OB
Monitors, lines for healthy cesarean
Std ASA monitors
- EKG, BP, pulse ox, ETCO2, Foley
- Two large bore IV catheters
- Forced air warmer
- IV fluid warmer
- Intermittent pneumatic compression stockings
- Consider a-line
Anesthesia choice for Placenta previa, accreta, increta, percreta
- Regional is ok for previa, accreta and increta
- Single shot is probably not good idea
- May need to convert to GA if massive bleeding
- General for percreta
Absolute and Relative contraindications to neuraxial anesthesia
Absolute
- Pt refusal
- Hypovolemia
- Infection at needle site
- Coagulopathies
- Mass lesions causing increased ICP
Relative
- Systemic infection (OK if treated)
- Neurological disease (rare)
- Isolated coagulation abnormalities
Expected blood loss
Vaginal 500 ml
Cesarean 1000 ml
Cesarean Hysterectomy 1500 ml
Physical findings of blood loss
< 20%
None
20-30%
Tachycardia, tachypnea
Narrowed PP
Orthostatic hypotension
30-40%
Worsening tachycardia and tachypnea
Hypotension
Oliguria
> 40%
Shock
Altered consciousness
Anuria
Postpartum hemorrhage causes
- Early <24 hrs, and late up to 6 weeks
- Bleeding from placental implantation site
Myometrial hypotonia (uterine atony)
Placenta previa
Retained placental tissue (accreta) - Bleeding from genital tract trauma
Lacerations
Uterine rupture - Coagulation deficits worsen bleeding
Physiology of placental separation
- At term 600 mL per minute flows in placenta
- With placental separation, spiral vessels are avulsed
- Myometrium contracts and compresses large vessels
- Next clotting occurs
- Often it is the lower uterine segment that has less myometrium which contracts poorly
Drugs and maneuvers to enhance myometrial coagulation
- Manual uterine massage
- Uterotonic medications
Oxytocin (Pitocin is synthetic oxytocin)
Increase frequency and duration of contactions
20 units in 1L crystalloid
Can cause hypotension via decreased SVR
Ergot alkaloids
Methylergonovine (Methergine) IM
Tetanic contractions
Avoid in hypertensive
Risk of coronary artery spasm
Prostoglandins
15-methyl prostaglandin F2 (Hemabate, Carboprost)
Avoid in asthma (bronchoconstriction)
When to transfuse?
Never if Hgb > 10
Always if Hgb < 6
Usually if Hgb < 7
Otherwise if evidence of inadequate oxygen carrying capacity
Can you use intraoperative blood salvaging in OB?
Yes, in circumstances with massive hemorrhage and the blood bank is depleted or pt refuses blood bank. Anti-D immune globulin if mother is Rh -