General Medicine Flashcards

1
Q

Which regions does Crohn’s affect?

A
  • mouth to anus
  • skipped lesions
  • most commonly terminal ileum
  • transmural inflammation
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2
Q

Which regions does UC affect?

A
  • sigmoid and rectum
  • continuous lesion
  • widespread ulcerations
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3
Q

Empiric treatment for pyelonephritis?

A

amoxi -clav or ciprofloxacin

longer duration than cystitis

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4
Q

Severe pyelonephritis tx

A
  • amoxicillin plus gentamicin
  • gentamicin must be monitored
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5
Q

First line basic AB tx for UTI

A
  • trimethoprim
  • cephalexin

pregnancy -> nitrofuratoin or cephalexin or amoci-clav

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6
Q

What is stage 1 HTN?

A

140-159/90-99

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7
Q

What is stage 2 HTN?

A

160-179 / 100-109

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8
Q

What is stage 3 HTN?

A

> 180 / > 110

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9
Q

What is normal blood glucose level?

A

3.9-5.5mmol/L

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10
Q

What is normal fasting blood glucose level?

A
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11
Q

Most likely cause of pneumaturia with bacilluria and UTI?

A

colovesical fistula - caused by mainly diverticulitis

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12
Q

What are the alarm symptoms of GERD?

A
  • dysphagia
  • odynophagia
  • weight loss
  • haemetemesis
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13
Q

When is pH monitoring indicated for GERD?

A
  • failure of initial treatment plan
  • uncertainty of diagnosis
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14
Q

When is endoscopy indicated for GERD?

A
  • alarm symptoms
  • uncertainty of diagnosis
  • failure of initial tx
  • long standing troublesome symptoms
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15
Q

Treatment for GERD initially?

A
  • PPI 4-8 weeks
  • H2 antagonists may also be used
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16
Q

What is the murphy sign and where is it found?

A
  • acute cholecystitis
  • inspiration halted during deep palpation of gallbladder
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17
Q

Where is the meckel’s diverticulum ?

A
  • 2 inches from the ileocecal valve
  • most common congenital cause of painless blood in stool
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18
Q

Difference between transudate and exudate pleural effusion, example for each.

A
  • transudate < 30g/L
    e.g. HF
  • exudate > 30g/L
    e.g. inflammatory cause -> infection like pneumonia or neoplasm
19
Q

Lights criteria for exudative effusion

A

One of the following:

  • pleural fluid protein to serum protein ratio greater than 0.5
  • pleural fluid LDH to serum LDH ratio greater than 0.6
  • pleural fluid LDH more than two-thirds the normal upper limit for serum
20
Q

What are the autoAB for SLE

A
  • ANA
  • ant-Dna
21
Q

What are the autoAB for RA

A
  • initial RF
  • Anti- CCP (specific)
22
Q

What are the autoAB for Autoimmune hepatitis

A
  • Anti-smooth muscle
23
Q

What are the autoAB for diffuse (CREST syndrome) and limited scleroderma?

A
  • limited: anti-scl70
  • Diffuse (CREST syndrome): anti-centromere
24
Q

What are the autoAB for primary biliary cholangitis

A

anti-mitochondrial

25
What are the autoAB for churg strauss syndrome
p-ANCA
26
What are the autoAB for wegener's granulomatosis
c-ANCA
27
What are the autoAB for drug induced lupus, give examples of drugs.
anti-histone SHIP Sulfonamides Hydralazine Isoniazid Procainamide
28
What is in the well's criteria? What are the scores?
- recent surgery or immobilisation - any malignancy - previous DVT or PE - haemoptysis - clinical symptoms of DVT - HR > 100 low - < 2 high - > 4
29
What is in the PERC criteria?
- estrogen use - age > 50 - HR > 100 - Previous DVT or PE - Recent surgery - unilateral swelling 0 - exclude PE 1 or more -> D dimer
30
Treatment of low severity of pneumonia?
Amoxicillin
31
Treatment of moderate severity penumonia?
benzypenicillin and azithromycin
32
Treatment of severe pneumonia?
Ceftriaxone and azithromycin
33
Treatment of aspiration pneumonia (anaerobes I believe)
IV ampicillin-sulbactam
34
Tx of chronic bronchiectasis exacerbation
Ticarecillin - clavunate
35
Acute exacerbation of bronchiectasis
doxycycline
36
Treatment for moderate pneumonia (no penicillin)
-ceftriaxone and azithromycin
37
Treatment for severe pneumonia (no penicillin)
- ceftriaxone and azithromycin
38
Treatment for moderate/severe pneumonia - when peniclillin or ceph can't be used
moxifloxacin
39
High yield info for aspiration pneumonia?
- ingestion of gastric content or oropharyngeal secretion e.g. dental caries or GERD/hernia - foul smelling sputum
40
Causative agent for aspiration?
- mainly klebsiella - anaerobes -> hence use of IV ampicillin/Sulbactam
41
Bronchiectasis high yield findings
- copious amount of green sputum - dilated bronchioles on imaging - chronic productive cough
42
Management of bronchiectasis
w/o pneumo = amoxicillin / amoxi-clav w pneumo = ticarcillin-clav acute - doxyc pseudomonas - ciprofloxacin
43