General Hormones Flashcards

1
Q

ACTH

A

Adrenocorticotropic hormone, corticotropin
Activated by CRF (corticotropin-releasing factor)
Controls cortisol production in adrenal gland

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2
Q

TSH

A

Thyroid-stimulating hormone, thyrotropin
Upregulated by TRH
↑T3, T4 upon stress

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3
Q

FSH

A

follicle-stimulating hormone
stimulate estrogen and progesterone/testosterone and sperm
GnRH
follicle development
downregulated by progesterone and estrogen

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4
Q

LH

A

luteinizing hormone
stimulate estrogen and progesterone/testosterone and sperm
GnRH
causes ovulation

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5
Q

PRL

A

Prolactin
milk production
supressed by dopamine
inhibits GnRH and FSH

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6
Q

ADH

A

anterior pituitary, neurohormone
Vasopressin
Contracts smooth muscle, raises blood pressure
allows water to diffuse into the blood (recruits aquaporins)

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7
Q

oxytocin

A

made in hypothalamus, released by posterior pituitary
↑ during orgasm and hugging, during labour
contractions of uterus

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8
Q

hGH

A

released from anterior pituitary
somatotropin, human growth hormone
Provides nutrients for ATP synthesis
adipose tissue –> ↑lipolysis (↓cholesterol) –> ↑FFA and glycerol
muscles –> ↑ protein synthesis, glucose, AA
bones –> ↑glucose, AA, protein synthesis, BMD, chondrogenesis
Liver –> ↑ gluconeogenesis, glycogenolysis
↑IGF-1
↑Cardiac function
↑muscle mass, strength

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9
Q

IGF-1

A

somatomedin, insulin-like growth factor

inhibits GHRH

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10
Q

GHIH

A

somatostatin

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11
Q

Aldosterone

A

mineralocorticoid
produced in adrenal gland
salt and water balance, blood pressure

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12
Q

Cortisol

A

glucocorticoid

maintains blood sugar and blood pressure, antiinflamamtion

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13
Q

What increases insulin secretion

A
↑glucose, FFA, AA
incretins (gastrin,cholecystokinin, GIP)
glucagon, GH, cortisol
PSN (acetylcholide)
beta adrenergic simulation
insulin resistance
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14
Q

glucagon

A
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15
Q

Ghrelin

A

↑Appetite, fat deposition

↑GH release

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16
Q

Leptin

A

↓appetite
from white adipose tissue
triggered by insulin and emotional stress
less leptine –> less POMC (makes ACTH) –> less cortisol
less leptine –> more neuropeptide Y, stimulated carbohydrate intake

17
Q

CCK

A

cholecystokinin
peptide
fat and protein digestion

18
Q

PYY

A

Peptide tyrosine tyrosine

↓appetite, limit food intake

19
Q

estrogen

A

Growth of tissues of sex organs

Strengthens bones, protective effect on the hearth

20
Q

progesterone

A

stimulates uterus lining for fertilization

inhibits FSH and LH

21
Q

androgen

A

kick starts puberty, stimulates pubic and underarm hair

testosterone is an androgen

22
Q

Testosterone

A

hair growth, muscle development, bone strengthening

23
Q

Corticosteroid

A

Produced in adrenal gland
Anti inflammatory, blood sugar levels, muscle strength
ex: prednisone

24
Q

globulin

A

protein, immune clotting

25
Q

albumin

A

protein, colloid osmotic pressure

26
Q

fibrinogen

A

protein, blood coagulation

27
Q

Catecholamines

A

tyrosine and AA derived

dopamine, Ne, serotonin

28
Q

What decreases insulin secretion

A
↓blood glucose
fasting
GHIH
alpha-adrenergic activity
leptin (hunger inhibition)
29
Q

Insulin promotes

A

↑Glucose effect
↑Glycolysis
↑Glycogen synthesis
↑protein synthesis

30
Q

Insulin inhibits

A

gluconeogenesis, glucigenolysis, lipoysis, ketegenesis, proteolysis