General Hormones Flashcards
ACTH
Adrenocorticotropic hormone, corticotropin
Activated by CRF (corticotropin-releasing factor)
Controls cortisol production in adrenal gland
TSH
Thyroid-stimulating hormone, thyrotropin
Upregulated by TRH
↑T3, T4 upon stress
FSH
follicle-stimulating hormone
stimulate estrogen and progesterone/testosterone and sperm
GnRH
follicle development
downregulated by progesterone and estrogen
LH
luteinizing hormone
stimulate estrogen and progesterone/testosterone and sperm
GnRH
causes ovulation
PRL
Prolactin
milk production
supressed by dopamine
inhibits GnRH and FSH
ADH
anterior pituitary, neurohormone
Vasopressin
Contracts smooth muscle, raises blood pressure
allows water to diffuse into the blood (recruits aquaporins)
oxytocin
made in hypothalamus, released by posterior pituitary
↑ during orgasm and hugging, during labour
contractions of uterus
hGH
released from anterior pituitary
somatotropin, human growth hormone
Provides nutrients for ATP synthesis
adipose tissue –> ↑lipolysis (↓cholesterol) –> ↑FFA and glycerol
muscles –> ↑ protein synthesis, glucose, AA
bones –> ↑glucose, AA, protein synthesis, BMD, chondrogenesis
Liver –> ↑ gluconeogenesis, glycogenolysis
↑IGF-1
↑Cardiac function
↑muscle mass, strength
IGF-1
somatomedin, insulin-like growth factor
inhibits GHRH
GHIH
somatostatin
Aldosterone
mineralocorticoid
produced in adrenal gland
salt and water balance, blood pressure
Cortisol
glucocorticoid
maintains blood sugar and blood pressure, antiinflamamtion
What increases insulin secretion
↑glucose, FFA, AA incretins (gastrin,cholecystokinin, GIP) glucagon, GH, cortisol PSN (acetylcholide) beta adrenergic simulation insulin resistance
glucagon
Ghrelin
↑Appetite, fat deposition
↑GH release