General EM Flashcards
what is the most common congenital heart abnormality associated with WPW
Ebstein anomaly
definition of status epilepticus
seizure lasting longer than 5 minutes OR 2 or more seizures without regaining consciousness between them
key historical features when assessing seizure in the ED
presence of a preceding aura, abrupt or gradual onset, progression of motor activity, loss of bowel or bladder control, presence of oral injury, and whether the activity was localized or generalized and symmetric or unilateral, duration of the episode and determine the presence of postictal confusion or lethargy.
common precipitating factors for seizures in epilepsy patients
missed doses of antiepileptic medications; recent alterations in medication, including dosage change or conversion from brand name; sleep deprivation; increased strenuous activity; infection; electrolyte disturbances; and alcohol or substance use or withdrawal.
first line in status epilepticus
lorazepam 2mg IV
second line in status epilepticus
phenytoin loading dose 20mg/kg .. rate of 50mg/min
third line, refractory status epilepticus
propofol 1mg/kg IV
risk factors for aortic dissection
- chronic hypertension
- Marfan, Ehlers-Danlos, bicuspid aortic valve, famhx of dissection
- chronic cocaine or amphetamine use
- previous cardiac surgery
Stanford classification Type A aortic dissection means
any dissection involving ASCENDING aorta
Stanford classification Type B aortic dissection
dissection involving only the descending aorta
3 historical features most highly associated with aortic dissection
abrupt onset, pain described as ripping or tearing, severe in intensity
physical exam findings in aortic dissection
SBP or pulse deficit in extremities, new onset aortic insufficiency murmur, focal neuro deficit PLUS chest, abdo or back pain, and shock or hypotension
CXR findings in aortic dissection
widened mediastinum, abnormal aortic contour, displacement of aortic intimal calcification from previous CXR, pleural effusion, or deviation of trachea, bronchus, or esophagus
imaging study to diagnose aortic dissection
CT angiogram with contrast
goal blood pressure in aortic dissection
below 120mmHg systolic
agent of choice for bp lowering in aortic dissection
short-acting β-blockers such as propranolol, labetalol, or esmolol are preferred over long-acting β-blockers.
management of type A aortic dissection
surgery, endovascular repair
diagnosis of temporal arteritis
need 3 of 5;
- age > 50
- new headache
- temporal artery abnormality (tender, decreased pulsation)
- ESR > 50
- abnormal temporal artery biopsy
risk factors for subarachnoid hemorrhage
Hypertension Smoking Excessive alcohol consumption Polycystic kidney disease Family history of subarachnoid hemorrhage Coarctation of the aorta Marfan's syndrome Ehlers-Danlos syndrome type IV α1-Antitrypsin deficiency
BP target in aortic dissection
below 120/80
BP target in ischemic stroke
receiving thrombolysis - below 185/110
no thrombolysis- treat if above 220/120 (lower by 15%)
BP target in intraparenchymal hemorrhage
SBP below 180 - INTERACT2 trial showed no benefit for below 140
risk factors for venous thromboembolism
age > 50
obesity, BMI >35 increases risk
pregnancy/postpartum state
prior VTE (highest recurrence for unprovoked)
solid cancers (adenocarcinomas and metastatic disease highest risk)
hematologic (acute leukemias and myeloma have highest risk)
thrombophilias (non O blood type, Factor V Leiden, lupus AC, protein C/S deficiency, shortened aPTT)
recent surgery (endotracheal intubation or epidural anesthesia within past 4 weeks)
immobility (2 contiguous joints highest risk, ie. long arm cast)
bed rest (becomes risk at 72 hours)
indwelling catheters (ie. PICC)
travel (flights >6 hours)
CHF (related to systolic function)
stroke (greatest in 1st month after)
estrogen (highest in first few months of use)
non-infectious inflammatory conditions (IBD, lupus, nephrotic syndrome)
syndrome that occurs in patients with PE who have a PFO
paradoxical embolism syndrome - due to shower of emboli through R–>L shunt due to increased right sided pressure due to PE, causes stroke like symptoms