General definitions

Question 1

What is the function of CRP?

Answer 1

CRP is an acute phase protein, produced in the liver, to opsonise pathogens and activate the complement cascade.

Question 2

What cells form the innate immune system?

Answer 2

APCs - Mast, dendritic and macrophage
Phagocytes - neutrophils and macrophages
Granulocytes - neutrophils, eosinophils, mast, basophils

Question 3

What is a cytokine?

Answer 3

A soluble tissue factor that has chemical signals to modulate cell activity and attract cells with chemokines

Question 4

What is the function of the complement cascade?

Answer 4

Opsonisation
MAC formation
Activation and chemoattraction

Question 5

What are the acute phase proteins?

Answer 5

IL-1, IL-6 and TNFalpha

Question 6

Which cytokines suppress an immune response?

Answer 6

TGFbeta and IL-10

Question 7

What cells make up the adaptive immune system?

Answer 7

B cells and T cells and high affinity antibodies

Question 8

What is the difference between innate and adaptive immune response?

Answer 8

Innate:
Rapid, no memory, low specificity, pre-programmed identical response

Adaptive:
Specific, antibody memory, slower

Question 9

What cells are derived from the lymphoid lineage?

Answer 9

B and T lymphocytes and DC cells.

Mostly associated with adaptive immunity.

Question 10

What cells are derived from the myeloid lineage?

Answer 10

Erythrocytes, monocyte/macrophage, eosinophils, basophils, neutrophils.
Associated with the innate immune system.