General Anesthetics

Question 1

Nitrous Oxide

Answer 1

• Inhaled
• Other
• High Fa/F1
• Low Blood/Gas partition coefficient

Question 2

Halothane

Answer 2

• Inhaled
• Hydrocarbon
• Low Fa/F1
• High Blood/Gas partition coefficient (ie. too soluble)
• as a general rule, high rate of metabolism has increased change of toxicity

Question 3

Isoflurane

Answer 3

• Inhaled
• Ethers
• Moderate Fa/F1
• Moderate Blood/Gas partition coefficient

Question 4

Sevoflurane

Answer 4

• Inhaled (90’s)
• Ethers
• Moderate Fa/F1- Moderate Fa/F1
• Moderate Blood/Gas partition coefficient

Question 5

Desflurane

Answer 5

• Inhaled (90’s)
• Ethers
• Moderate Fa/F1
• Moderate Blood/Gas partition coefficient

Question 6

Thiopental

Answer 6

• IV
• Barbiturate
• Rapid Induction of Hypnosis
• AE: Hypotension

Question 7

Propofol

Answer 7

• IV
• Used for sedation and maintenance of anesthesia
• Pleasant dreams
• AE: Hypotension

Question 8

Ketamine

Answer 8

• IV
• Dissociative anesthesia (patients appear conscious)
• Battlefield surgery
• Bad dream
• Antagonists at NMDA

Question 9

Etimidate

Answer 9

• IV
• Similar to action of propofol
• Produces adrenal suppression