GENERAL ANATOMY Flashcards
What is the smallest unit of heredity?
A. Gene
B. Cell
C. Chromosome
D. Nucleotide
A. Gene
Explanation:
A gene is the smallest functional unit of heredity. It is a specific segment of DNA that contains instructions for making proteins, which determine inherited traits.
Why the Other Options Are Incorrect:
❌ B. Cell
The cell is the basic unit of life, but it is not the smallest unit of heredity.
❌ C. Chromosome
A chromosome is a structure composed of many genes, so it is larger than a single gene.
❌ D. Nucleotide
A nucleotide is the building block of DNA and RNA, but it does not function independently as a hereditary unit.
Which of the following is classified as a start codon?
A. AUG
B. UAG
C. UGA
D. UAA
A. AUG
Explanation:
The start codon is the first codon of an mRNA transcript that signals the beginning of translation. AUG codes for methionine (Met) and serves as the universal start codon in most organisms.
Why the Other Options Are Incorrect:
❌ B. UAG, C. UGA, D. UAA
These are stop codons, which signal the termination of protein synthesis rather than initiation.
UAG → Amber (Stop Codon)
UGA → Opal (Stop Codon)
UAA → Ochre (Stop Codon)
What best describes the anatomic position?
A. A person standing semi supine, with feet flat on the floor, face forward, with hands on the side, palms forward
B. A person standing upright, with feet flat on the floor, face forward, with hands not on the side, palms forward
C. A person standing upright, with feet flat on the floor, face sideward, with hands on the side, palms forward
D. A person standing upright, with feet flat on the floor, face forward, with hands on the side, palms forward
D. A person standing upright, with feet flat on the floor, face forward, with hands on the side, palms forward
Explanation:
The anatomic position is the standard reference position in anatomy. It is described as:
✅ Standing upright
✅ Feet flat on the floor, slightly apart
✅ Face forward (looking straight ahead)
✅ Arms at the sides
✅ Palms facing forward (supinated)
This position is used as a baseline for describing directions and locations of body structures.
Why the Other Options Are Incorrect:
❌ A. “Standing semi-supine” → Incorrect, because the person should be fully upright, not semi-supine.
❌ B. “Hands not on the side” → Incorrect, because the hands should be at the sides.
❌ C. “Face sideward” → Incorrect, because the face should be forward.
What plane divides the body into anterior and posterior halves
A. Sagittal
B. Axial plane
C. Coronal plane
D. Para sagittal
C. Coronal plane
Explanation:
The coronal plane (frontal plane) is the vertical plane that divides the body into anterior (front) and posterior (back) halves.
Why the Other Options Are Incorrect:
❌ A. Sagittal plane → Divides the body into left and right halves.
❌ B. Axial plane (Transverse plane) → Divides the body into superior (upper) and inferior (lower) halves.
❌ D. Parasagittal plane → A non-midline sagittal cut that divides the body into unequal left and right portions.
This lies between the right and left pleura in and near the median sagittal plane of the chest. It extends from the sternum in front to the vertebral column behind, and contains all the thoracic viscera except the lungs.
A. Thoracic cavity
B. Cardiothoracic cavity
C. Mediastinal cavity
D. Pleural cavity
C. Mediastinal cavity
Explanation:
The mediastinum is the central compartment of the thoracic cavity, located between the right and left pleural cavities. It extends from the sternum (front) to the vertebral column (back) and contains all the thoracic organs except the lungs. It houses the heart, great vessels, esophagus, trachea, thymus, and lymph nodes.
Why the Other Options Are Incorrect:
❌ A. Thoracic cavity → A broader term that includes the mediastinum and both pleural cavities (where the lungs are located).
❌ B. Cardiothoracic cavity → Not a standard anatomical term. “Cardiothoracic” refers to the heart and chest region but isn’t used to describe a specific cavity.
❌ D. Pleural cavity → The space surrounding each lung, lined by the pleura, and does not contain the heart or other thoracic organs.
The appendix is an organ found on which abdominal region
A. Right Iliac
B. Right Hypochondriac
C. Right lumbar
D. Right Hypogastric region
A. Right Iliac
Explanation:
The appendix is a small, tube-like structure attached to the cecum (the first part of the large intestine). It is located in the right iliac region, which is the lower right portion of the abdomen, near the right inguinal area. This region is commonly associated with appendicitis, which presents as pain starting around the umbilicus and later localizing to the right iliac fossa (McBurney’s point).
Why the Other Options Are Incorrect:
❌ B. Right Hypochondriac → Contains the liver and gallbladder, not the appendix.
❌ C. Right Lumbar → Contains the ascending colon and right kidney, but not the appendix.
❌ D. Right Hypogastric → No such anatomical term; perhaps meant to be hypogastric region, which is the central lower abdomen and contains the bladder and part of the intestines, but not the appendix.
Proprioceptors are found in each of the following except
A. Pulp
B. PDL
C. Gingiva
D. TMJ
A. Pulp
Explanation:
Proprioceptors are sensory receptors that detect position, movement, and force within muscles, joints, and connective tissues. They are crucial for occlusal force regulation and jaw movement coordination.
✅ Found in:
- Periodontal Ligament (PDL): Detects bite force and tooth position.
- Gingiva: Contains mechanoreceptors contributing to oral tactile sensation.
- Temporomandibular Joint (TMJ): Rich in proprioceptors to monitor jaw movement and positioning.
❌ Not found in:
Dental Pulp: The pulp contains nociceptors (pain receptors), but it lacks proprioceptors because it does not play a role in detecting movement or pressure.
Kidney, spleen, lymph nodes and bone marrow are what type of tissue?
A. Reticular
B. Cartilaginous
C. Adipose
D. Connective
A. Reticular
Explanation:
Reticular tissue is a type of loose connective tissue that forms a supportive framework (stroma) in various organs. It consists of reticular fibers (a type of collagen fiber) and reticular cells that help support immune and blood-forming cells.
✅ Found in:
- Kidney (supports filtration structures)
- Spleen (supports immune cells)
- Lymph nodes (provides a scaffold for lymphatic cells)
- Bone marrow (supports blood cell formation)
Other Options:
❌ B. Cartilaginous → Found in joints, ear, nose, and trachea, but not in these organs.
❌ C. Adipose → Fat-storing tissue, not a supportive framework.
❌ D. Connective → Too broad; reticular tissue is a specific type of connective tissue.
Which cellular junction is damaged in pemphigus vulgaris?
A. Macula adherens
B. Zona occludens
C. Pemphigus
D. Macula lutea
A. Macula adherens
Explanation:
Pemphigus vulgaris is an autoimmune blistering disease caused by autoantibodies targeting desmosomes, specifically desmoglein-1 and desmoglein-3, which are found in macula adherens (desmosomes).
Key Points:
✅ Desmosomes (Macula Adherens): Provide strong cell-to-cell adhesion in epithelial tissues.
✅ Damage to desmosomes leads to acantholysis (loss of intercellular connections), causing blisters and erosions in the skin and mucous membranes.
✅ Clinical sign: Positive Nikolsky sign (skin sloughs off with slight pressure).
Other Options:
❌ B. Zona occludens (Tight junctions) → Involved in barrier function, not affected in pemphigus vulgaris.
❌ C. “Pemphigus” → Not a cellular junction, just part of the disease name.
❌ D. Macula lutea → A part of the retina, unrelated to cell adhesion.
The type of tissue present in the lining of kidney tubules, and ducts of salivary glands.
A. Squamous
B. Cuboidal
C. Columnar
D. Oblique
B. Cuboidal
Explanation:
Simple cuboidal epithelium is commonly found in structures involved in secretion and absorption, such as:
✅ Kidney tubules → Assists in filtration and reabsorption.
✅ Ducts of salivary glands → Helps in secretion of saliva.
Other Options:
❌ A. Squamous → Found in areas requiring diffusion, like alveoli and blood vessels (capillaries).
❌ C. Columnar → Found in areas needing absorption and mucus secretion, like the intestines and respiratory tract.
❌ D. Oblique → Not a recognized epithelial tissue type.
What is the functional unit of compact bone
A. Osteoid
B. Osteon
C. Osteocytes
D. Osteoblast
B. Osteon
Explanation:
The osteon (also called Haversian system) is the functional and structural unit of compact bone. It consists of:
✅ Central (Haversian) canal → Contains blood vessels and nerves.
✅ Concentric lamellae → Rings of bone matrix surrounding the central canal.
✅ Osteocytes → Bone cells trapped within lacunae, maintaining the bone.
✅ Canaliculi → Small channels for communication between osteocytes.
Other Options:
❌ A. Osteoid → Unmineralized organic bone matrix produced by osteoblasts.
❌ C. Osteocytes → Mature bone cells that maintain bone structure.
❌ D. Osteoblasts → Cells responsible for bone formation.
The alveolar bone proper is also known as the cribriform plate because it microscopically reveals minute openings which represent?
A. Areas of osteoclastic activity
B. Regions of hematopoietic activity
C. Attachment sites of Sharpey’s fibers
D. Regions for passage of vascular and nerve elements
D. Regions for passage of vascular and nerve elements
Explanation:
The alveolar bone proper (also called the cribriform plate) is a thin layer of bone that lines the tooth socket. It appears perforated under a microscope, which allows for the passage of blood vessels, nerves, and lymphatics between the bone and the periodontal ligament (PDL). These openings contribute to the bone’s vascularity and innervation, ensuring nourishment to the surrounding structures.
Other Options:
❌ A. Areas of osteoclastic activity → Osteoclastic resorption occurs, but the perforations in the cribriform plate are not due to bone resorption.
❌ B. Regions of hematopoietic activity → Hematopoiesis occurs in bone marrow, but the alveolar bone proper is not a major hematopoietic site.
❌ C. Attachment sites of Sharpey’s fibers → Sharpey’s fibers attach the PDL to the alveolar bone, but they are embedded within the bone, not forming perforations.
Radiograph of which teeth is most likely to demonstrate the coronal process of the mandible?
A. Mandibular molars
B. Maxillary molars
C. Mandibular 8’s
D. Mandibular anteriors
B. Maxillary molars
Explanation:
The coronoid process of the mandible is an upward bony projection of the mandible located anterior to the condyle. It serves as the attachment site for the temporalis muscle.
On dental radiographs, the coronoid process can be seen superimposed on maxillary molar periapical or panoramic images due to its anatomical position. Since the coronoid process extends superiorly when the mouth is open, it can sometimes project into the area of the maxillary third molars in radiographs.
Other Options:
❌ A. Mandibular molars → The coronoid process is a mandibular structure but is located too high to appear in mandibular molar radiographs.
❌ C. Mandibular 8’s (third molars) → The coronoid process is anterior to the mandibular third molars and does not appear in their radiographs.
❌ D. Mandibular anteriors → These radiographs focus on the front teeth, far from the coronoid process.
_______ is a cone-shaped paired depression deep to the infratemporal fossa.
A. Pterygopalatine fossa
B. Sphenopalatine fossa
C. Pterygopalatine process
D. Sphenopalatine process
A. Pterygopalatine fossa
Explanation:
The pterygopalatine fossa is a small, cone-shaped, paired depression located deep to the infratemporal fossa. It serves as a major neurovascular hub, connecting the orbit, nasal cavity, and maxillary region.
Anatomical Location:
*Boundaries:
- Anterior: Posterior wall of the maxilla
- Posterior: Pterygoid process of the sphenoid bone
- Medial: Perpendicular plate of the palatine bone
- Lateral: Opens into the infratemporal fossa
*Contents:
- Maxillary nerve (V2)
- Pterygopalatine ganglion
- Branches of the maxillary artery
- Venous plexus
Other Options:
❌ B. Sphenopalatine fossa → Not an anatomical term; likely confused with the sphenopalatine foramen, which connects the pterygopalatine fossa to the nasal cavity.
❌ C. Pterygopalatine process → No such anatomical structure exists.
❌ D. Sphenopalatine process → Incorrect; likely referring to the sphenopalatine foramen or pterygopalatine fossa.
Interval between the bones in the midline of the cranial base of a newborn child consists of:
A. Hyaline cartilage
B. Elastic cartilage
C. Fibrous cartilage
D. Fibrous connective tissue
A. Hyaline cartilage
Explanation:
In a newborn child, the midline of the cranial base (e.g., the spheno-occipital synchondrosis) consists primarily of hyaline cartilage. This allows for continued endochondral ossification, which contributes to cranial base growth during early development.
Key Points:
- The cranial base forms through endochondral ossification, unlike the cranial vault, which develops through intramembranous ossification.
- Hyaline cartilage is present in synchondroses, which are cartilaginous joints that allow for controlled growth before eventually ossifying.
Important midline synchondroses include:
- Spheno-occipital synchondrosis
- Intersphenoidal synchondrosis
Why Not Other Options?
❌ B. Elastic cartilage → Found in structures requiring flexibility (e.g., ear, epiglottis), not in cranial base development.
❌ C. Fibrous cartilage → Found in intervertebral discs and pubic symphysis; not a component of the cranial base.
❌ D. Fibrous connective tissue → Found in cranial sutures of the skull vault, but not in the cartilaginous growth centers of the cranial base.
Which cartilage can undergo ossification?
A. Hyaline
B. Elastic
C. Fibrocartilage
D. Pseudocartilage
A. Hyaline
Explanation:
Among the different types of cartilage, hyaline cartilage is the one that can undergo ossification through endochondral ossification. This process is essential in bone development, particularly in the formation of long bones and the cranial base.
Key Points About Hyaline Cartilage Ossification:
- Found in growth plates (epiphyseal plates) of long bones.
- Found in the cartilage model during fetal development before being replaced by bone.
- Present in synchondroses of the cranial base (e.g., spheno-occipital synchondrosis).
- Undergoes calcification before being replaced by bone tissue.
Why Not Other Options?
❌ B. Elastic Cartilage → Does not ossify; remains flexible (e.g., ear, epiglottis).
❌ C. Fibrocartilage → Contains dense collagen fibers; resistant to compression but rarely ossifies (e.g., intervertebral discs, pubic symphysis).
❌ D. Pseudocartilage → This is not a true type of cartilage.
The articulating surfaces of the temporomandibular joint are covered by
A. Hyaline cartilage
B. Elastic cartilage
C. Vascular fibrous tissue
D. Fibrous or fibrocartilage tissue
D. Fibrous or fibrocartilage tissue
Explanation:
Unlike most synovial joints, which have hyaline cartilage covering their articulating surfaces, the temporomandibular joint (TMJ) is unique in that it is covered by fibrous or fibrocartilage tissue instead.
Key Points About TMJ Articulating Surfaces:
- The TMJ is a synovial joint but has fibrous (or fibrocartilage) covering, which makes it different from most other joints.
- Fibrocartilage is more resistant to mechanical stress and wear compared to hyaline cartilage, which is why it is found in high-stress joints like the TMJ.
The articulating surfaces include:
- Condyle of the mandible
- Articular eminence of the temporal bone
- Mandibular (glenoid) fossa
Why Not Other Options?
❌ A. Hyaline cartilage → Found in most synovial joints, but not in the TMJ.
❌ B. Elastic cartilage → Found in flexible structures like the ear and epiglottis, not in joints.
❌ C. Vascular fibrous tissue → TMJ is covered by fibrocartilage, which is mostly avascular.
The bifurcation of the trachea lies at the level of the
A. Sternal angle
B. Xiphosternal junction
C. Second thoracic vertebra
D. Attachment of the fourth costal cartilage to the sternum
A. Sternal angle
Explanation:
The bifurcation of the trachea (where it splits into the right and left primary bronchi) occurs at the level of the sternal angle (Angle of Louis), which is at the level of the T4-T5 intervertebral disc.
Key Points About the Tracheal Bifurcation:
- The trachea divides into the right and left main (primary) bronchi at the carina, an important anatomical landmark.
- This occurs at the sternal angle, which is the junction between the manubrium and the body of the sternum.
- This landmark is useful in chest X-rays and clinical examinations to identify important thoracic structures.
Why Not the Other Options?
❌ B. Xiphisternal junction → Located lower, around T9, near the diaphragm.
❌ C. Second thoracic vertebra → Too high, the tracheal bifurcation occurs lower, around T4-T5.
❌ D. Attachment of the fourth costal cartilage to the sternum → This is not a standard anatomical landmark for the tracheal bifurcation.
Foramen transversarium is seen on all cervical vertebra except
A. C1
B. C3
C. C5
D. C7
D. C7
Explanation:
The foramen transversarium is a distinguishing feature of cervical vertebrae. It is present in all cervical vertebrae (C1-C6) and serves as a passage for the vertebral artery and vein. However, in C7, the foramen transversarium is usually small or absent and does not transmit the vertebral artery (only small veins may pass through it).
Key Points About Foramen Transversarium:
- Present in C1-C6, allowing passage of the vertebral artery, vertebral vein, and sympathetic nerves.
- In C7, the foramen transversarium is often rudimentary or absent and typically transmits only accessory veins (not the vertebral artery).
Why Not the Other Options?
❌ A. C1 (Atlas) → Has foramen transversarium for the vertebral artery.
❌ B. C3 → Has foramen transversarium for the vertebral artery.
❌ C. C5 → Has foramen transversarium for the vertebral artery.
The most anterior bone of the pelvis is the
A. Ileum
B. Ilium
C. Ischium
D. Pubis
D. Pubis
Explanation:
The pubis is the most anterior bone of the pelvis. It is one of the three bones that form the hip bone (os coxae) along with the ilium and ischium.
The pubis consists of:
- Superior pubic ramus
- Inferior pubic ramus
- Pubic body, which forms the pubic symphysis, a cartilaginous joint that connects the left and right pubic bones at the midline of the pelvis.
Why Not the Other Options?
❌ A. Ileum → Incorrect spelling; the correct term is “Ilium.”
❌ B. Ilium → The largest and superior part of the hip bone, but not the most anterior.
❌ C. Ischium → Forms the posterior and inferior part of the hip bone; supports body weight when sitting.
The TMJ is classified as what type of lever?
A. Class I
B. Class II
C. Class III
D. Class B
C. Class III
Explanation:
The temporomandibular joint (TMJ) functions as a Class III lever because the force (effort) is applied between the fulcrum and the load (resistance).
In a Class III lever:
- Fulcrum → The TMJ (condylar head in mandibular fossa)
- Effort → The muscles of mastication (e.g., masseter, temporalis, and pterygoids) pulling on the mandible
- Load → The resistance of food being chewed
Why Not the Other Options?
❌ A. Class I → A Class I lever has the fulcrum between the effort and the load (e.g., a seesaw). The TMJ does not work this way.
❌ B. Class II → A Class II lever has the load between the fulcrum and the effort (e.g., a wheelbarrow). This is not how the TMJ functions.
❌ D. Class B → Not a recognized classification of levers.
This is considered as the main stabilizing ligament of the TMJ which prevents posterior and inferior displacement of the jaw.
A. Capsular ligament
B. Lateral ligament
C. Sphenomandibular ligament
D. Stylomandibular ligament
B. Lateral ligament
Explanation:
The lateral ligament (also called the temporomandibular ligament) is the main stabilizing ligament of the TMJ. It plays a crucial role in:
- Preventing posterior displacement of the mandible
- Preventing excessive inferior (downward) movement of the jaw
- Providing lateral stability to the TMJ
Why Not the Other Options?
❌ A. Capsular ligament → This encloses the TMJ, but it is not the primary stabilizer. It mainly helps contain the synovial fluid and provides some support.
❌ C. Sphenomandibular ligament → This ligament limits excessive opening of the mouth but is not the main stabilizer.
❌ D. Stylomandibular ligament → This ligament helps limit excessive protrusion of the mandible but does not primarily stabilize the TMJ.
Which bone forms majority of the palate.
A. Palatine
B. Maxilla
C. Nasal
D. Sphenoid
B. Maxilla
Explanation:
The maxilla forms the majority of the hard palate. Specifically, the palatine processes of the maxilla make up the anterior two-thirds of the hard palate, while the horizontal plates of the palatine bone form the posterior one-third.
Why Not the Other Options?
❌ A. Palatine → Contributes to the posterior part of the hard palate but does not form the majority.
❌ C. Nasal → Forms part of the nose, not the palate.
❌ D. Sphenoid → Helps form the cranial base and contributes to the pterygoid processes, but not the palate.
What is the largest foramen in the human body?
A. Obturator foramen
B. Foramen magnum
C. Acetabulum
D. Subpubic foramen
A. Obturator foramen
Explanation:
The obturator foramen is the largest foramen in the human body. It is a large, oval opening in the pelvic bone formed by the ischium and pubis. Despite its size, it is mostly covered by the obturator membrane, with only a small canal (the obturator canal) allowing for the passage of nerves and blood vessels.
Why Not the Other Options?
❌ B. Foramen magnum → While it is the largest foramen in the skull, it is not the largest in the entire body.
❌ C. Acetabulum → This is the socket of the hip joint, not a true foramen.
❌ D. Subpubic foramen → No such anatomical structure exists.