General Anaesthetics

Question 1

Analgesia

Answer 1

Loss of pain

Question 2

General anaesthetics have relatively low therapeutic indices

Answer 2

which necessitates

the monitoring of patients when they are used.

Question 3

4 Stages of Analgesia

Answer 3

1. Initial analgesia (loss of pain).
2. Excitement/delirium, with loss of consciousness
   (hypnosis) , but with heightened reflexes. QUICK!
3. Surgical anaesthesia, with all reflexes disappearing
   as stage deepens. Respirator may be used with
   endotracheal tube.
4. Final stage of medullary paralysis, with respiratory
   failure and death. This is why patient monitoring is
   crucial

Question 4

GAs are usually administed

Answer 4

1. IV

2. Inhalation

Question 5

Depolarising Muscle Relaxants:

Answer 5

these are nACh and mACh
receptor agonists at the neuromuscular junctions.
–> Blocks muscle for temp. paralysis (3-5min)

Question 6

Nondepolarising Muscle Relaxants:

Answer 6

these are competitive

ACh receptor antagonists