General

Question 1

Buerger disease is..

Answer 1

thromboangiitis obliterans

chronic thrombosing inflammatory disease of small and medium arteries and veins of arms and legs

Question 2

epidemiology

Answer 2

uncommon in US
Much more common in Asia
male
Onset usually in 20s (before age 40)

Question 3

Pathology

Answer 3

two phases

1. acute phase
2. chronic phase

Question 4

acute phase

Answer 4

segmental transmural acute inflammation, with granulomas and giant cells
WITHOUT necrosis

Question 5

most characteristic of acute phase…

Answer 5

thromboses with “microabscesses” in thrombus

Question 6

chronic phase

Answer 6

nonspecific organization and recanalization of thrombus w/ neovascularization and fibrosis

Question 7

Signs and symptoms

Answer 7

instep claudicaton
cold feet
Raynaud’s phenomenon
migrating superficial nodular thrombophlebitis

Question 8

complications

Answer 8

ulcers and gangrene

Question 9

Diagnosis

Answer 9

History and physical exam!

Angiogram?

Question 10

Angiogram shows

Answer 10

stenosis (more distally) with corkscrew collaterals

Question 11

Treatment

Answer 11

cessation of smoking

amutation

Question 12

Peripheral vascular disease diagnoses made by Hx and physical exam…

Answer 12

Peripheral arterial disease
Acute arterial occlusion
Buerger disease

Question 13

Raynaud’s phenomenon

Answer 13

vasospasm of finger arteries w/ cold exposure

causes tri-color response:

1. fingers turn white from cutoff of arterial blood supply
2. then blue from accumulation of deoxygenated hemoglobin
3. then red from resumption of arterial blood flow

Question 14

What is the most essential aspect of treatment of Buerger disease?

Answer 14

getting the pt to quit smoking

Question 15

Buerger disease is associated with

Answer 15

SMOKING!!! (100%)