General Flashcards
1
Q
1st hyperoxaluria MOI and cause?
A
AR, reduce liver alaine glyoxylate aminotransferase
2
Q
CUA ddx
A
PVD ulcer herpes zoster vasculitis pyoderma gangrenosum atheroemboli cryoglobulinemia warfarin induced systemic oxalosis
3
Q
systemic CUA sym?
A
myopathy, hypotension, fever, dementia, stroke, bowel ischemic, IHD
4
Q
CUA dx?
A
clinical
transcutaneous oxygen sat, bone scan, xeroradiography
biopsy potentially induce ulcer
5
Q
CUA Tx?
A
stop VitD, Ca supp, increase dialysis regime low Ca HD / PD cinacalcet / parathyroidectomy Vit K supp Na thiosulfate (SE: HAGMA) IV 25g (12.5 if BW < 60) after HD over 60min x 3 months bisphosphonate
6
Q
resistive index?
A
PSV - EDV / PSV
> 0.8: Renal disease, ureteric obstruction
In CRT can be due to ATN, RVT, rejection, drug toxicity, ureteric obstruction
7
Q
New agent for anemia in CKD?
A
Hypoxia-inducible factor stablizer:
prolyl hydroxylase inhibitors
8
Q
causes of EPO hyporesponsiveness?
A
Fe deficiency: ferritin < 1000, Fe% 35 Inadequete dialysis hyperPTH B12 / folate deficiency BM failure (MDS, MM) Chronic infection / malignancy chronic blood loss Aluminium toxicity pure red cell aplasia due to Anti EPO
