General

Question 1

Progressive dyspnea, cough, facial swelling, neck vein distention

Answer 1

Superior vena cava syndrome

Most common cause is lung cancer.

Question 2

Headache, vomiting, altered mental status with focal neurologic deficit and loss of consciousness

Answer 2

Increased intracranial pressure

Lumbar puncture is contra indicated. Immediate treatment with glucocorticoids.

Question 3

Volume a pleural fluid that can be drained and still avoid re-expansion pulmonary Edema

Answer 3

1500 mL or less.

Question 4

Methods to cause obliteration of the pleural space and avoid recurrent effusion

Answer 4

Tetracycline, bleomycin, talc

Question 5

Chemotherapeutic associated with pulmonary toxicity

Answer 5

Bleomycin

Mitomycin

Question 6

Chemotherapeutic associated with cardiac toxicity

Answer 6

Doxorubicin

Question 7

Chemotherapeutic associated with kidney toxicity

Answer 7

Cisplatin

Ifosfamide

Question 8

Medications that can induce hemolysis in G6PD deficiency (the most common enzyme deficiency)

Answer 8

Sulfonamides, anti malarial, rasburicase

Question 9

Factor VIII deficiency

Answer 9

Hemophilia A

Question 10

Factor IX deficiency

Answer 10

Hemophilia B

Question 11

Which clotting factor has the shortest half-life?

Answer 11

Factor VII,

Will see elevated PTT in severe DIC

Question 12

Given to replace clotting factors

Answer 12

FFP

Question 13

Given to correct fibrinogen

Answer 13

Cryoprecipitate

Question 14

Transfusion reaction with presentation like heart failure and hypertension due to volume overload

Answer 14

TACO, diurese and slow infusion rate

Question 15

Transfusion reaction with fever, chills, hypotension and dyspnea

Answer 15

TRALI,

Stop the transfusion and support

Question 16

Adverse effect trastuzumab (herceptin)

Answer 16

Cardiac toxicity (CHF)
Check echo

Question 17

CRAB criteria for multiple myeloma

Answer 17

Hypercalcemia (>11)
Renal failure (>2)
Anemia (Hb <10)
Bone disease