General Flashcards

1
Q

What is autologous cell therapy?

A

Stem cells are removed from a person, stored, and later given back to that same person.

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2
Q

What is allogeneic cell therapy?

A

Stem cells are removed from a person, stored and then given to a different person.

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3
Q

What are the benefits of autologous cell therapy?

A

Immunocompatibility

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4
Q

What are the problems with marketing allogeneic cell therapy?

A

People are iffy over cells from another person.

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5
Q

What are the 5 main stages involved with cell therapy? H.S.A.S.A

A
Harvesting stem cells.
Selection of desired cells.
Amplicification. 
Screening. 
Administration. 

Amplification and screening stages reversed?

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6
Q

What are iPS?

A

Induced pluripotent stem cells (also known as iPS cells or iPSCs) are a type of pluripotent stem cell that can be generated directly from adult cells.

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7
Q

What are the problems with iPS?

A

Tumorigenicity.
Integration of gene delivery vectors and transgenes into host cells. Chromosomal damage, clonal expansion of oncogenic cells, incomplete reprogramming, DNA damage accumulation.

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8
Q

What is the Encaptra drug delivery system?

A

It is a biological/artificial device for diabetes treatment.
It is a semi-permeable containment barrier surrounding a cell therapy. This cell therapy can output insulin, amylin, glucagon etc and use nutritional inputs such as glucose, O2, proteins etc.

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9
Q

What is xenotransplantation?

A

Transplantation of living cells, organs or tissues from one species to another.

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10
Q

What are the main problems with xenotransplantation?

A

Immune rejection,
Life span issues (low)
Cross-species infections.

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11
Q

What are the main problems with transplants in general?

A

Immune rejections.

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