General Flashcards
anticholinergics
hold all in
Rx: supportive, bicarb if arrythmis, wide qrs
benzo for sz
general work for toxicology
gluc
ECG
lytes
Opiates - morphine, heroine, methadone
sedation
miosis
cinfusion
Cholinergic treatment
decontaminant
supportive
atropine
what are syndromes associated with pyloric stenosis?
Cornelia de Lange
Smith lemli Opitz
Apert syndrome
T 18
serotonin syndrome
alt mental status
neuromuscular hyperactivity
autonomic instability
Rx SSRI OD
supportive care
cyproheptadine
rabies Rx
rabies vaccine(5 dose) and rabies Immunoglobilin - administer into the wound or IM
3 contraindication to ketamine
allergic
uncontrolled HTN
neuropsychiatry state
retropharyngeal abscess on xray
air fluid level
widened preveretbral space
ibuprofen OD
non anion gap metabolic acidosis
apnea
polydipsia
renal dysfunction
pseudoporphyria causes
small hypopigmented scars after small trauma
vesicles in sun exposed areas
caused by NSAID
what med taken in pregnancy causes fetal hypothyroidism
amiodarone + goiter
What are the clinical features of SLE
MD SOAP BRAIN
Malar rash – butterfly rash, sparing of nasolabial folds
Discoid rash –basement mb involved, may cause scarring
Serositis – pleuritis/pericarditis
Oral ulcers
Antinuclear antibody (ANA) – very sensitive test
Photosensitivity – skin rash to sunlight
Blood – haemolytic anaemia, leukopaenia, low PLT
Renal disorder – proteinuria and cell casts
Arthritis – symmetrical, 2+ small or large peripheral joints
Immunological disorder – anti-dsDNA
Neurological – seizures, psychosis
what urological condition should be ruled out in a pelvic fracture?
urethral transection injury
Post renal injury, what is a child at risk for?
HTN, needs periodic BP
what are the CP of cardiac tamponade
tachycardia low arterial BP narrow pulse pressure pulses paradoxus-excessive fall of systolic blood pressure (>10 mm Hg) with inspiration muffled HS distended neck veins - inc JVP
What are clinical features of Carbon monoxide poisoning
HA confusion/dizzy Nausea arrythmia - cardiac arrest rhabdo cherry red skin Sz
How do you treat CO poisoning?
worry if carboxyHb > 25%
- 100% O2
- if CarbHb > 25% - hyperbarric chamber
what are the clinical features of cholinergic overdose (organophosphates/carbamates)
DUMBELLS Diaphoresis Urinary and fecal incontinence Miosis Bradycardia/bronchorrhea Emesis Lacrimation Lethargy Salivation
what is the mgnt of organophosphate poisoning
- decontaminate - remove clothing
- Atropine to competitively inhibit Ach at muscarinic receptor
- Pralidoxine - breaks bong btw OP and enzymes - helps clear
- PICU monitoring for nicotinic effects - Sz, delirium, HTN, inc HR, arryth
what are the clinical features of TCA OD
- anticholinergic toxidrome:
- delirium,
- mydriasis - dilated
- dry mucous membranes,
- tachycardia,
- hyperthermia,
- urinary retention, and slow GI motility. - CNS toxicity - lethargy, coma, myoclonic jerks, and seizures
- Blockade of fast Na channels - wide QRS, arrythmia
how do you manage TCA OD
- activated charcoal if possible
- Alkalinalize - HCO3
- Treat arrythmia - lidocaine or MgSo4
- Sz with benzo
- Low BP with Norepinephrine
MUST avoid Na blocking agents
is dialysis effective in TCA OD
No
after how long can you DC a ? TCA OD if they remain asymptomatic?
can DC after 6 hours if well
what are poor prognostic factors when dealing with submersion injury
Orlowski scale:
- submersion> 5 min
- Age < 3
- time to CPR initiation > 10 min
- Coma
- Ph < 7.1 in ED
what are good prognostic factors for submersion injuries?
ROSC in < 10 min
Sub < 5 min
PERL at scene
NSR at Scene
GCS improvement in first 24-72 - best for CNS outcomes
if pt post head trauma has one asymmetrical pupil that is not responding to light, what CN is effected
CN III due to temporal herniation
how do you treat a hypertensive crisis?
continuous infusion of labetalol or nicardipine
gaol to decrease BP by 20-25 % over the first 8 hours
what is a hypertensive emergency?
symptomatic HTN
what is the most common cause of pediatric deaths in children ged 12-24 mnths
submersion injury
how do you manage a submersion injury
C-spine!!!!! if diving, alcohol, ? trauma give cricoid pressure if doing BMV try to decompress stomach rewarm correct hypoglycemia monitor for coagulopathy
what parts of the skin are involved if superficial burn and what would it look like
Epidermis only red pain NO BLSITERS heal 3-5 days
What does a superficial partial burn look like and what parts of the skin are affected
epidermis + 1/2 of dermis pain MOIST BLISTERS heals in 2 weeks
what layers are involved in a deep partial thickness burn and at does it look like?
epidermis and >1/2 dermis pale dry less pain speckled need graft
WHat layers are involved in a full thickness burn and what does it look like?
into subcutaneous tissu pale charred leathery NO PAIN
what are important steps when managing burns
cover with steriledressing early cooling to prevent further injury Tetanus analgesia measure COHb monitor for low glucose NO ABX
when do we intubate a burn?
singed nasal hair
soot in airway
soot in sputum
hoarsness
what is the parkland formula?
for > 5 yrs
4cc/kg/BSA over 24 hours - 1st hlf in 8 hours, 2nd half in 16 hours
ADD TO MAINTENANCE
use NS
what are the admission criteria for burns? 8
- Suspected non accidental
- > 10% BSA fr partial thickness
- > 2% BSA full thickness
- > 1% BSA of hands/feet/face/perineum
- circumferencial
- inhalation injury
- electrical injury with high tension wire
- Associated trauma
what are the 3 criteria for an ALTE?
apnea
colour change
tone change
frightening for care taker
patient has spinal shock - what HR and/or BP support will you give
if brady - Dopamine and Epi
if hypotensive - Norepinephrine
what lab values will be consistent with a chylothorax?
high TGL
lymphocytes
labs similar to serum
high Ig
if pre-renal failure, what is your FeNa
< 1%
Urine Na < 20
Serum BUN/Creat > 20:1
Urine Osm > 500
if your cause is a acute tubular necrosis, what is you Fraction excretion of Na
> 2%
Urine Na > 40
serum BUN/crea < 20:1
urine Osm > 300
what is the WU for acute renal failure
U/A and R&M Lytes BUN, creat Lytes Urine lytes and Osm Cytstatin C, iCa, Mg, PO4 VBG AUS ECG for high K
what are the indications for dialysis?
AEIOU Acidosis Electrolytes - HIGH K, HIGH PO4, low Na Ingestion - methanol, ethylene, ASA, Li Overload Uremia - pericarditis, SZ...
how do you declare brain death?
- Established etiology capable of causing neurological injury in absence of reversible conditions
- No confounders including:
- Deep unresponsive coma (GCS 3)
Absent brainstem reflexes:
Fixed, dilated pupils, Cough, Gag, Corneal, Vestibulo-ocular (eg cold caloric), Motor response - Absent respiratory effort as measured by apnea test
- Ancillary tests: if cannot perform an element of clinical NDD (angiography or nuclear med)
what is the apnea test?
Preoxygenate
Disconnect from vent
Observe for absence of resp effort AND PaCO2 ≥ 60mmHg AND rise ≥ 20mmHg
what are the differences in brain death declarations?
Children ≥ 1yo = no difference
Children ≥ 30d and < 1yo = 2 separate exams separated by time interval (interval not specified)
Children < 30 days: minimum time from birth 48h, 2 exams separated by at least 24h
what are complications post submersion injury
Cerebral edema - ICP is bad ARDS - myocardial dysfunction DIC ischemic bowel
what ECG findings are consistent with Hypothermia
bradycardia flipped T wave 1st degree AV block Osborn J wave - VF
reasons to transfer a burn to a burn center?
Partial or full thickness burns: >10% in pt < 10 yrs 20% in other age groups Burns of face, hands, feet, genitalia, perineum or major joints. Electrical/chemical burns Inhalation injury Pre-existing conditions that may complicate mgmt. Concomitant trauma Special social, emotional, rehab support