general Flashcards

1
Q

furosemide is contraindicated in a person with…

A

any urinary obstruction because it makes you have to pee and it would be difficult to do so with an obstruction

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2
Q

IgA nephritis presents how?

A

asymptomatic hematuria with upper respiratory tract infection or GI infection

also has trace proteinuria and can have GI manifestations as well

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3
Q

acute interstitial nephritis

A

rapidly developing immune mediated tubulointerstitial injury from medications, infection, or other causes. NSAIDs

fevers, rash, joint pain

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4
Q

lupus nephritis presentation

A

can present with hematuria, but also +ANA and low C3 and C4

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5
Q

post streptococcal glomerulonephritis

A

hematuria presents 1-2 weeks after respiratory infection + proteinuria. low C3 and C4

treatment is supportive (control BP and fluid volume). resolves on its own.

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6
Q

diagnostic tools for bladder cancer

A

cystoscopy, bladder biopsy, IV pyelogram

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7
Q

diagnostic tools for renal/uretal stones

A

IV pyelogram

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8
Q

to look for renal cell carcinoma

A

CT scan

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9
Q

RTA type 1

associated with?

A

associated with SLE (nephrocalcinosis and nephrolithiasis) or other autoimmune disorders, liver cirrhosis, sickle cell, lithium use, amphotericin B

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10
Q

what does RTA type 1 look like electrolytes wise?

A

non anion gap acidosis, low plasma bicarbonate, high urine pH, low serum H+, decreased K, nephrocalcinosis and nephrolithiasis

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11
Q

MOA of stones in RTA type 1

A

MOA decreased kidney capacity for hydrogen ion secretion in the collecting tubules

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12
Q

treatment for RTA type 1

A

oral bicarbonate

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13
Q

what does RTA type 2 look like?

A

high urine pH with low urine output, decreased K, osteomalacia and rickets

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14
Q

MOA of RTA type 2

A

no proximal tubular bicarbonate absorption

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15
Q

treatment for RTA type 2

A

volume restriction first, then high dose bicarbonate and/or thiazide

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16
Q

MOA of RTA type 4

A

Adrenal/Aldosterone deficiency

17
Q

what does RTA type 4 look like?

A

Na excretion with K-H retention, hyperkalemia,

18
Q

treatment for RTA type 4

A

Fludrocortisone

19
Q

side effects of furosemide (loops)

A

metabollic alkalosis (with excessive use)

20
Q

how do you correct furosemide overdose?

A

acetazolamide to force the kidneys to excrete bicarb thus reacidifying the blood.

21
Q

how do you treat rhabdomyalisis?

A

saline hydration, mannitol, bicarbonate, and an EKG to rule out life threatening hyperkalemia

22
Q

signs and symptoms of uremia

A

anorexia, nausea, vomiting, uremic pericarditis, “uremic frost”, delirium, seizure, coma

23
Q

nephritic syndrome PHAROH

A

proteinuria (<1.5 g/day), hematuria, azotemia, RBC casts, oliguria, HTN

24
Q

TYPEs of nephritic syndrome

A

post strep glomerular nephritis, IgA nephropathy, Wegeners, Good Pastures, Alports, Lupus nephritis.

25
Q

Types of nephrotic syndrome

A

Minimal Change disease, membranous, membranoproliferative, focal segmental, Amyloidois, Diabetic nephropathy, Lupus nephritis.

26
Q

renal colic caused by renal stones first step in management is?

A

NSAIDs and fluids!

Not abdominal ultrasound

27
Q

how do you treat a pt with pyelonephritis?

A

outpatient with oral cipro

if they seem septic (shaking chills, fevers, hi leukocytes), treat inpatient with IV gentamicin, IV ceftriaxone, or IV ampicillin, or IV fluroquinolone. Once better, switch to outpt treatment for 14 days.

28
Q

microhematuria following minor trauma in a child is suggestive of…?

the first step of workup is..?

A

congenital anomaly of the genitourinary system

sonogram