General Flashcards
What is Pharmacokinetics?
-Drug Absorption
-Distribution
-Metabolism
-Elimination
Idiopathic?
Not well understood
Describe the blood brain barrier?
Lipid soluble can go through, ex. O2, CO2, anesthesia
Water soluble need active transport, ex. glucose, urea, proteins, antibiotics
Define:
ac?
pc?
bid?
tid?
qid?
AC: before meal
PC: after meal
2x/day
3x/day
4x/day
Define:
Dose?
Dosage?
Dose: one time amount
Dosage: the regime if the Rx(frequency, amount, # of doses)
What is a drug classification?
Drug defined by what it does/how it does it. Classes with similar drugs. A drug may belong to more than one class. Ex. Aspirin=antipyretic, analgesic, anti-inflammatory.
What is a contraindication?
Factor that prohibits administration of drug.
What is an adverse drug effect?
Unpredictable, serious, harmful rxn of drug administered at normal dose
What is an adverse drug rxn?
Any harmful effect on body due to drugs (therapeutic or abused)
What is a side effect?
Secondary, unintended, predictably cause
What are the 5 factors affecting absorption?
-Route of Administration
-Ability of the med to dissolve
-Blood flow to the site
-Body surface area
-Lipid solubility
Absorption is greatest in the..?
Small Intestine
3 factors influencing distribution?
-Circulation
-Membrane Permeability
-Protein Binding
What are the 10 rights?
-Right pt
-Right drug
-Right dose
-Right route
-Right time
-Right documentation
-Right reason
-Right to refuse
-Right to educate pt
-Right evaluation
When do you check the drug label?
3 checks:
-Before/picking out the med
-During dispensing
-After/putting away
What does active form of drug mean?
Unbinded
What are main organs for metabolism?
Main: liver
Also: kidneys, blood, intestines
Main organ for excretion?
Main: kidneys
Also: liver, bowel, lungs(alcohol and anesthetic), exocrine glands(lipid soluble)
What does biotransformation mean?
Med becoming a less active form, aka metabolism
Define med orders:
Single?
Stat?
Now?
Prn?
Asap?
Single: once, anytime
Stat: once, immediately
Now: 90min
Prn: as needed
Asap: write down
Meds can be submitted on?
-CF2003
-CFHIS
-DND1618
-CF2138
Screening vs Diagnostic test?
Screening: first test to check for an abnormality
Diagnostic: determines what you got