General Flashcards

1
Q

define meiosis

A

reduction division wherby chromosoma number is halved from diploid to haploid for the production of gametes

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2
Q

Chromosome characteristics?

A

single stranded dna molecules around histone protein in chromatin network

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3
Q

Explain the formation of a homologous pair and what it is?

A

Homologous is a pair of chromosomes with same structure and purpose
Interphase dna replication occurs double the number of chromosomes in the form of two chromatids joined by centromere

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4
Q

Autosomes vs Gonosomes?

A

autosomes are chromosomes that determine features first 22
gonosomes determine sex and is 23rd pair
xx female
xy male

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5
Q

Why are haploid gametes required?

A

overcome the doubling effect of fertilization

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6
Q

Importance of Meiosis (3)?

A

1- overcome doubling effect
2- keep chromosomal number constant through generations
3- genetic variance through crossing over and random assortment to ensure survival through evolution

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7
Q

Explain Downs Syndrome

A

Abnormal meiosis and chromosomes during oogenesis don’t split properly in anaphase 1
This is a form of anuploidy as there will be an extra chromosome in the daughter cell
where one has two on chromosome 21
fertilization occurs and a zygote is formed wherby 23+24=47 and this results in extra pair of chromosome
hence trisomy-21
effect feature- flat face, retard and heart defects

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8
Q

what is a bivalent

A

paternal and maternal chromatids that lie next to each other from two chromosomes as a result of synapsis

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9
Q

define karyotype
and what does it show

A

computer diagram of chromosomes during metaphase organized by size and shape
show sex and abnormalities

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