General Flashcards

1
Q

Phase 2 …glucuronic acid ?

A

(🧑‍⚕️MAC)
Aspirin …morphine….chloramphenicol

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2
Q

Phase 2…Acetic acid (acetylation)?

A

☄️hip☄️
Isoniazid…hydralazine…procainamide

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3
Q

Phase 2 methylation?

A

Noradrenaline

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4
Q

Phase2 glycine?

A

Aspirin

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5
Q

Phase 2 sulfation?

A

Steroids

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6
Q

Basic drugs ?

A

Ephidrine….amphetamine

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7
Q

Acidic drugs,?

A

Aspirin ….barbiturate

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8
Q

Increase rate of gastric empyting ?

A

Metoclopramide

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9
Q

Decrease rate of gastric empyting ?

A

Atropine

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10
Q

1- Rapid disintegration?
2- slow disintegration,?

A

1- paracetamol
2-digoxin

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11
Q

Hepatic first pass?

A

Pass through liver and distructed via enzymes….(mlpnn)
Morphine …nitroglycrine…lidocaine…propranolol…natural sex hormone

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12
Q

Hepatic enzymes inducers

A

Phenobarbitone
Phenytoin
Carbamazepine
Rifampicin
Androgen
Tobacco smoke

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13
Q

hepatic enzymes inhibitors specific

A

Cimetidine
Ciprofloxacin
Chloramphenicol
Erythromycin
Estrogen
Valproic acid

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14
Q

Hepatic enzymes inhibitors non-specific?

A

hepatotoxic drugs &drugs decreasing hepatic blood flow
as propranolol & cimetidine

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15
Q

Cause absent limbs (phocomelia)

A

thalidomide

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16
Q

Cardiac septal defect

A

Aspirin

17
Q

Cleft palate

A

Phenytoin

18
Q

Hepatotoxicity

A

halothane and paracetamol

19
Q

Nephrotoxicity

A

NSAID and aminoglycosides

20
Q

Neurotoxicity 8 nerve

A

Streptomycin

21
Q

Drugs for Alzehimer’s disease?

A

Galantamine
Rivastigmine
Donepezil

22
Q

Must be injected very rapidly IV?

A

Thiopental
Diazoxide
(Because they are highly bound to plasma protein)

23
Q

Drug not suitable for males as it produces infertility?
……………

كلوربرومازين

A

Chlorpromazine

24
Q

Iatro genic disease,? Drug induced diseases?

A

Salicylate and corticosteroids cause peptic ulcer
Phenothiazine and antisychotics cause parkinsonism