Gene Expression and Regulation Flashcards
What mechanisms regulate gene expression.
Activators, Repressors, DNA methylation, histone modification.
Transcription factors:
Proteins that bind to specific DNA sites to enhance or inhibit RNA polymerase binding.
Transcriptional control:
Regulates how much and whether a gene is transcribed into mRNA
Translational control:
Regulates how much and whether mRNA is translated into protein
Post-translational control:
Regulates whether a protein is active or inactive, and whether it is stable or degraded
Transcription factors:
Proteins that bind to specific DNA sites to enhance or inhibit RNA polymerase binding
Activators:
Transcription factors that induce gene expression
Repressors:
Transcription factors that reduce gene expression
DNA methylation:
A chemical modification of DNA that regulates gene expression
Histone modification:
A chemical modification of histones that regulates gene expression
Operon
A regulatory unit that includes: a promotor (where RNA polymerase attaches), an operator (this will enhance or impede RNA polymerase) and the gene sequence to produce a polypeptide.