Gender Flashcards
Which were unethical issues associated with the Tuskegee Syphilis trials?
- Treatment known to be effective existed, and was withheld
- No consent given
- False information was provided to recruit participants
- The experiment was conducted on a poor, marginalized population
True or false: In the Tuskegee Syphilis experiment, if there had not existed a treatment for Syphilis at the time, the participants would not have needed to be informed about the study.
False. In the Tuskegee Syphilis experiment, even if there had not existed a treatment for syphilis at the time, the participants still should have been informed about the experiment.
True or false: In general, it is unethical to offer incentives to experimental participants?
False. It can be ethical to offer incentives to experimental participants to participate in a research experiment. Offering incentives can be helpful as a way to compensate participants for their time and for any costs incurred from participating in the experiment. However, the incentives cannot be unreasonably large.
What is the primary purpose of the Belmont Principles?
To define a set of core principles which researchers should adhere to in order to protect humans that are participants or subjects in research.
Which of the following correctly defines “research”?
A systematic investigation designed to generate generalizable knowledge. Usually, research in this sense is the type of research that is conducted involving human participants with the intention of publishing results at some point. In contrast, investigations that are conducted by organizations for internal use only are generally not considered research under this definition. For example, this includes companies that collect data on its customers with the goal of learning more about those customers, not for the purpose of generating generalizable knowledge or publishing their results. For example Google, Yahoo, OK Cupid, and other related companies collect extensive data on their customers, but this is generally not considered to be research under the definition above.
Which of the following correctly defines “human subjects”?
Human subjects are defined as any people from whom researchers collect information or obtain information through intervention or interaction with the individual. The Belmont principles are set out with the primary goal of protecting any human subjects that may be participants in a research study.
Which of the following correctly defines the second principle “beneficence”?
The second key principle of the Belmont principles, beneficence, requires that researchers maximize the benefits associated with a study, while minimizing the harms associated with the research study. This requires that the research will answer a question that has some benefit to society that justifies the use of humans as research subjects, and that at the same time takes steps to ensure that risks to those human subjects from participating in the research are minimized.
What are some of the steps that must be taken to ensure protection of human subjects?
- Ask for informed consent before collecting any personal data, or ensure that you have approval from an institutional review board to waive the requirement for informed consent, where applicable
- Keep all data in a safe place only accessible to the research team
Which of the following statements is true about randomizing treatment, according to the discussion in class?
Randomizing treatment to some people in a sample is ethical, since people have an equal chance of being chosen or not chosen for treatment, and since the control group would not be harmed from having treatment withheld
Which of the following correctly defines “undue inducement”?
Undue inducement refers to the practice of recruiting participants by providing too large of an incentive for people that participate. Researchers are allowed to recruit participants by offering an incentive to participate, but this incentive cannot be unreasonably large.
True or false: If you discover during the course of a research intervention that a particular intervention is highly effective, you are obligated to inform the IRB, who may instruct you to stop the research and enroll the control group in the treatment.
True. If during the course of research, investigators discover that there the intervention is highly effective, then they are obligated to inform the IRB who may ask them to stop the research and enroll the control group in the treatment.
Under which of the following conditions might a human subjects committee waive the requirement for receiving informed consent from research participants?
- Risks to the human subjects are minimal, and collecting informed consent would make the research impossible.
- Collecting informed consent might pose a greater risk to participants, if the researchers would not otherwise collect any personal information from them
Which of the following are examples of “dictatorial” households?
- A parent who make decisions on behalf of their children
- Husbands who make decisions on behalf of the wife
- Households with one member who makes all decisions
True or false: Dictatorial households, where one member makes decisions on behalf of other members, are always harmful for the non-decision makers.
False. Even in “dictatorial” households, it could be that the decision maker highly values the utility of other household members. In that case, the utility of other household members would feature very highly in the decision maker’s utility function. When the decision maker makes decisions on behalf of the other member, he or she would then be making these decisions with the other members’ best interests in mind. It could also be that the preferences of the dictator are closely aligned with the preferences of other household members, in which case by maximizing his or her own utility would similarly maximize the utility of the other members.
Which of the following correctly defines “unanimity” in households?
“Unanimity” in households refers to households where all members have the same preferences. In a “dictatorial” household with unanimous preferences, the dictator could make decisions on behalf of all other members, and everyone would be just as happy as if they had made the decisions themselves to maximize their own utility.