GE System-Panre Flashcards
Acute prostatitis (Level 2)
Most common cause is acute bacterial prostatitis → pts are typically acutely ill
with combination of irritative &/or obstructive urinary symptoms, perineal or
pelvic pain
● Most often occurs in young & middle-aged ♂; associated with presence of acute
bacterial urinary tract infection (UTI)
MC organisms in Acute prostatitis (Level 2)
Most common organisms:
○ Escherichia coli , Proteus species
○ If associated with sexually transmitted infection (STI), most common
organisms include Neisseria gonorrhoeae & Chlamydia trachomatis
Acute prostatitis (Level 2) S/S
Fever, chills, malaise, dysuria, urgency, frequency, pelvic
or perineal pain, pain at tip of penis, cloudy urine, sensation of incomplete bladder
emptying, dribbling of urine’ Prostate is exquisitely tender, swollen & firm (prostate massage is
generally contraindicated)
○ Pts may have generalized urosepsis
Acute prostatitis (Level 2) DX
Clinical
○ Urinalysis → WBCs & bacteria
○ Urine gram stain & culture
Acute prostatitis (Level 2) TX
Nontoxic pt: Trimethoprim-sulfamethoxazole (TMP/SMX) or
fluoroquinolone (eg. ciprofloxacin), analgesics, bed rest, stool softeners,
hydration
○ Toxic pts: Hospitalize; intravenous fluoroquinolone, ± aminoglycoside (eg.
gentamicin)
○ Appropriate referral or consult
Bacterial cystitis (Level 2)
Bacterial infection & inflammation of the urinary bladder
Copyright Hippo Education 2019 - All Rights Reserved 1
● Most commonly seen in ♀
Bacterial cystitis (Level 2) MC organism ?
Escherichia coli ( E. coli )
Bacterial cystitis (Level 2) Risk factors
Sexual intercourse, diaphragm & spermicide use, recent antibiotic use,
new sex partner within past year, structural or functional abnormalities of the
urinary tract, instrumentation of the urinary tract
Bacterial cystitis (Level 2) Uncomplicated vs complicated UTI
Uncomplicated: Premenopausal adult ♀ without structural or functional
abnormality of the urinary tract; ∅ pregnancy; ∅ significant comorbid
conditions
○ Complicated: Pregnancy, ♂ sex, structural or functional urinary tract
abnormality, poorly controlled diabetes mellitus, chronic kidney disease,
recent instrumentation of the urinary tract
Bacterial cystitis (Level 2) CM ?
Dysuria, urinary urgency & frequency, sensation of bladder
fullness, suprapubic pain & tenderness
Bacterial cystitis (Level 2) DX
Clinical
○ Dipstick urinalysis: Positive leukocyte esterase, ± blood, ± protein, ± nitrite
○ Microscopic urinalysis: >8-10 white blood cells/mL in a fresh, unspun urine
sample using hemocytometer chamber; bacteria, ± red blood cells
○ Urine culture is usually performed only for pts with complicated UTI
Bacterial cystitis (Level 2) TX?
First-line: Nitrofurantoin, TMP/SMX, or fosfomycin
○ Phenazopyridine for symptomatic dysuria: Turns urine reddish-orange
Benign prostatic hyperplasia (BPH) (Level 2)
Nonmalignant adenomatous overgrowth of the periurethral prostate gland →
varying degrees of bladder outlet obstruction
Benign prostatic hyperplasia (BPH) (Level 2) CM?
Weak stream, hesitancy, urinary urgency & frequency,
nocturia, sensation of incomplete bladder emptying, terminal dribbling, overflow or
urge incontinence
Benign prostatic hyperplasia (BPH) (Level 2) Dx?
Clinical: ↑ prostate gland size, rubbery consistency, loss of median furrow
○ Urinalysis
○ Prostate-specific antigen measurement for patients between 50-69 yo after
shared decision making discussion
Benign prostatic hyperplasia (BPH) (Level 2) TX ?
5-α-reductase inhibitors (eg. finasteride)
○ α-blockers (eg. terazosin)
○ Appropriate referral as needed for further work-up & treatment
Bladder cancer (Level 1)
Carcinoma of transitional epithelium (most common type)
● High recurrence rate (70% in 5 yrs)
● 4 th most common CA in men (♂:♀=3:1)
Median age at diagnosis: 65 yo
Bladder cancer (Level 1) Risk factors
Smoking: #1 most common and most important
○ Aromatic amines (eg. aniline dyes),
○ Analgesic abuse
○ Chronic irritation (eg. chronic catheterization)
Bladder cancer (Level 1) CM
Painless gross or microscopic hematuria → most common
(classic presentation in 80-90%)
○ Also may have dysuria, urgency, frequency
Bladder cancer Dx:
Clinical
○ Urinalysis
Bladder cancer tx
Appropriate referral: cystoscopy with biopsy
Hydrocele
Fluid collection within the tunica vaginalis or processus vaginalis of the scrotum
○ Most commonly seen in boys (rare in girls)
Hydrocele Types ?
types:
○ Communicating (most common): Residual communication of the processus
vaginalis with the peritoneum → peritoneal fluid accumulation
■ Usually seen between ages: newborns~1-2 yo
○ Noncommunicating: Usually occurs in older children
■ May be idiopathic or associated with epididymitis, orchitis,
testicular torsion or tumo
Hydrocele CM?
Communicating hydroceles: Size may fluctuate throughout the day (larger
during the day, smaller at night) or with straining or crying
■ Often reducible with application of pressure
○ Noncommunicating hydroceles: Size is constant & non-reducible
○ Testis may palpable posterior to the fluid collection
○ Positive transillumination (homogeneous glow without internal shadows
Hydrocele DX?
Clinical
○ If indicated, ultrasound study (eg. inability to palpate testis, internal
shadows on transillumination)
Hydrocele TX?
Observation until 1-2 yo; possibly surgery
Varicocele
Dilation of the pampiniform venous plexus & internal spermatic vein; ~85-95%
occur on the left side
● Associated with ♂ infertility
○ ~35% of subfertile or infertile ♂ have varicocele, but only 10-15% of ♂
with varicoceles have fertility problems
Varicocele CM
Usually asymptomatic & may be discovered in a man
seeking evaluation for infertility;
○ Some patients have achy scrotal pain or heaviness especially with standing
Varicocele red flags?
Sudden onset, isolated right-sided, not reducible in supine
position
Varicocele Dx?
Clinical
○ If indicated, high-resolution color-flow Doppler ultrasonography (eg.
equivocal clinical examination, red flags
Varicocele Tx?
Usually observation & symptomatic treatment (eg. OTC analgesics);
appropriate urologic referral for adolescents or adults with significant pain or
discomfort; fertility work-up as indicated
Erectile dysfunction (ED) (Level 2)
Inability to either attain or sustain an erection satisfactory for sexual performance
Erectile dysfunction (ED) (Level 2) Primary ED?
Primary ED: ♂ who has never been able to attain or sustain an erection →
almost always due to psychological factors (eg. guilt, fear of intimacy,
depression, anxiety) or obvious anatomic abnormality
Erectile dysfunction (ED) (Level 2) 2nd Ed?
Usually acquired later in life in ♂ who have previously been
able to attain or sustain an erection and common due to:
■ Vascular disease: Atherosclerosis, HTN, DM, smoking
■ Neurologic disease: Diabetic neuropathy, stroke, multiple sclerosis,
autonomic neuropathies, spinal cord injury, complications of pelvic
(eg. prostate) surgery
■ Others: Drug effect (eg. β-blockers, alcohol), prolonged bicycle
riding, testosterone deficiency
■ Psychological factors: Performance anxiety, stress, depression
Erectile dysfunction (ED) (Level 2) CM?
Establish the presence or absence of erections:
■ Either nocturnally &/or upon awakening (psychogenic ED usually do
have these erections; organic ED often does not)
○ Examination for penile fibrous bands or plaques (eg. Peyronie disease),
testicular atrophy, rectal tone, perianal sensation, bulbocavernosus reflex,
peripheral pulses
ED DX?
Clinical: Screening for mental health (eg. depression), sexual health (eg.
satisfaction with relationship), underlying disorders (eg. DM)
○ Measure morning testosterone level: If ↓, measure prolactin & luteinizing
hormone
○ Additional laboratory testing as guided by signs & Sx
ED Tx?
Phosphodiesterase-5 inhibitors (eg. sildenafil)
■ Contraindication: Concomitant use of nitrates
○ Vacuum erection & constriction devices
○ Appropriate referral: Intraurethral or intracavernosal prostaglandin E1,
surgical implants
○ Treatment directed at any other underlying cause
Peyronie Disease
Curvature of penis from scar tissue (plaque) accumulation in tunica albuginea
● Risk factors: penile trauma, autoimmune dz, Dupuytren dz
● S/Sx: penile curvature, painful erections, erectile dysfunction, difficulty or inability to
have sexual intercourse
● PE: curvature noted on erection, palpable fibrosis, ‘hour-glass’ deformity (indentation of
shaft at plaque site)
● Labs: U/S for plaque delineation & presence of Ca++
● Tx: observation for minimal pain &/or mild curvature (<30°); otherwise, urology referral
Fecal incontinence (Level 1)
Impaired ability to control the passage of gas or stool
Fecal incontinence (Level 1) Etiologies?
Childbirth-related injury (most common), trauma to anal muscles (eg.
anal surgery), age-related loss of anal muscles strength, neurologic injury or
disease (eg. spinal cord injury, severe dementia, stroke), inflammatory diseases (eg.
ulcerative colitis), rectal tumor or prolapse
Fecal incontinence (Level 1) CM?
Range from difficulty controlling gas to inability to control
liquid & formed stools, sense of urgency
Fecal incontinence (Level 1) Dx?
Clinical
○ Evaluate sphincter function, perianal sensation on physical examination
Fecal incontinence (Level 1) TX?
Non-surgical: Bowel pattern management for enhanced predictability,
adequate fluid & dietary bulk intake, possibly constipating medications (eg.
loperamide), perianal muscle strengthening & biofeedback
○ Appropriate referral for additional work-up & treatment including surgery
Stones under what MM would be passed with no problem?
5mm
Nephrolithiasis:
Kidney stone
Urolithiasis
Stone in the genitourinary tract
Nephrolithiasis/urolithiasis (Level 2)
Precipitation of crystals in the urinary tract that can cause acute occlusion to the
passage of urine
● Most stones are calcium oxalate
Nephrolithiasis/urolithiasis (Level 2) CM?
May be asymptomatic or patients may present after
passing gravel or stone
○ ‘Classic presentation’: Nausea, vomiting, mild~excruciating pain that waxes
& wanes in severity, and develops in waves or paroxysms; stone location
often determines pain location:
■ Upper ureter or renal pelvis: Flank pain or tenderness
■ Lower ureter: Pain radiates to ipsilateral testis or labium
Nephrolithiasis/urolithiasis (Level 2) Dx?
Clinical
○ Urinalysis: Most patients will have gross or microscopic hematuria
○ CT scan of abdomen & pelvis without contrast: Preferred imaging study for
identifying stone & hydronephrosis
Nephrolithiasis/urolithiasis (Level 2) Tx?
Hydration (oral if possible; intravenous if unable)
○ Pain control: NSAIDs &/or opiates
○ Admit patients that cannot tolerate oral intake, or if they have fever &/or
uncontrollable pain
○ Possible administration of α-blocker (eg. tamsulosin) or Ca ++ -channel
blocker (eg. nifedipine) for facilitating stone passage
○ Have patient strain urine for several days & bring stone in for analysis
■ Most stones with diameter ≤ 5 mm pass spontaneously
○ Urology consult for urosepsis, acute kidney injury, anuria or intractable
pain, nausea or vomiting
■ Also for stone ≥10 mm or failure to pass stone with conservative
therapy
Struvite stones
(magnesium ammonium phosphate)
■ Form in patients with upper UTI due to urease-producing organisms
(eg. Proteus , Klebsiella ) → usually do not present with classic Sx/S;
instead, patients have recurrent UTI, mild flank pain or hematuria;
urine pH >7.0
Orchitis (Level 2)
Inflammation of the testes