Gatstroenteritis inc. HUS Flashcards

1
Q

What are the 2 mechanisms for bacteria to produce symptoms?

A

Invade bowel wall

produce toxin

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2
Q

What is the most common bacterial cause of gastroeneritis?

A

Campylobacter

serious in very young and old

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3
Q

What other bacteria can cause gastroenteritis?

A

Salmonella

E. coli 0157

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4
Q

What bacteria have a short incubation period of 1-6 hours? Why is this?

A

Staph aureus
Bacillus cereus
Preformed toxin in food leads to rapid absorption

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5
Q

What bacteria have a medium incubation period of 12-48 hours? Why is this?

A

Salmonella
Cl perfringens
invasion of bowel wall and toxin produced in gut

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6
Q

What bacteria have a long incubation period of 2-14 days? Why is this?

A

Campylobacter
E coli 0157
invasion of bowel wall and toxin produced in gut

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7
Q

Where is campylobacter most commonly spread from?

A

poultry and raw milk

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8
Q

Where is salmonella enteritidis most commonly spread from?

A

poultry, meat and raw egg

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9
Q

How are salmonellae typed?

A

O-antigen on body

Antigen on tail

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10
Q

How is E coli 0157 spread?

A

person-person

from food-person

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11
Q

Who are at risk of E coli 0157 complications

A

children and elderly

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12
Q

How does HUS present?

A
Abdo pain
fever 
pallor 
petechiae
oliguria
bloody diarrhoea in 90% cases
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13
Q

What is used to diagnose HUS?

A

LDH >1.5 x normal

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14
Q

What causes HUS?

A

verotoxin produced by E coli (not just 0157) leads to renal cell anc RBC death as well as other cells deaths

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15
Q

If a patient has HUS what should not be given?

A

Antibiotics
anti-motility agents
NSAIDs

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16
Q

Where can E coli 0157 be contracted from?

A

Contact with farm animals
Private drinking water
Burgers
unpasteurised dairy product

17
Q

If a patient has Ecoli 0157 or HUS what has to be done?

A

Contact Health Protection Unit

18
Q

What do bacteria need t multiply?

A

Time, temperature, food source, moisture

19
Q

How does acute enteritis present?

A

fever
D&V
abdominal pain

20
Q

How does acute colitis present?

A

fever
pain
bloody diarrhoea

21
Q

How does enteric fever like illness present? Typhoid presents like this

A
fever 
rigors 
abdo pain
constipation but possible short history of diarrhoea
tired 
muscle pains
22
Q

What infections can cause bloody diarrhoea?

A

Campylobacter
Shigella
E coli 0157
amoebiasis

23
Q

What is Guillain-Barre syndrome?

A

Post infectious sequalea of neurological symptoms

24
Q

How is enteric fever like illness (typhoid) diagnosed?

A
Blood culture (key)
stool and urine cultures
25
What does HUS consist of?
haemolytic anaemia acute kidney failure low platelet count (thrombocytopenia)
26
What is used to determine the severity of a CDI?
Suspicion of pseudomembranous colitis or toxic megacolon or ileus or colonis dilation WCC Creatinine
27
How is gastroenteritis treated?
``` oral rehydration #1 IV fluids anti-spasmodics? Anti-motility? (loperamide, opiates) antibiotics? ```
28
How is C diff described?
Anaerobic gram-positive spore forming bacillus
29
How is pseudomembranous colitis treated?
non-severe - metronidazole | severe - vancomycin