Gastrointestinal Reflux Flashcards
When antacids (such as Tagamet, Zantac, and Pepcid) are used for GERD, what is there mechanism of action?
antacids neutralize gastric acid and reduce esophageal acid to reduce heartburn. they alleviate esophagitis and prevent respiratory symptoms.
What do prokinetic medications (such as Reglan) do to help relieve GERD?
prokinetic medications promote esophageal peristalsis and accelerate gastric emptying.
Side effects of prokinetic medications (Reglan) include restlessness, drowsiness, and extrapyramidal reaction (involuntary movements that you can not control)
What surgical procedure can be done to help with GERD?
Nissen Fundoplication- this is when a portion of the fundus is wrapped around the lower portion of the esophagus. By doing so, the LES is reinforced and the likelihood of acid being backed up into the esophagus is decreased.
