Gastrointestinal Flashcards

Pathology

1
Q

Most common salivary gland tumor. Presents as Painless, mobile mass. Composed of cartilage and epithelium. Recurs frequently

A

Pleomorphic Adenoma

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2
Q

Where do most salivary tumors occur?

A

Parotid gland (most are benign)

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3
Q

Benign CYSTIC salivary gland tumor with germinal centers that grows in LYMPH NODES aka HETEROTOPIC GROWTH.

A

Warthin’s Tumor (Papillary Cystadenoma Lymphomatosum)

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4
Q

Most common MALIGNANT salivary gland tumor. Mucinous and squamous components Frequently painful due to involvement of the facial nerve.

A

Mucoepidermoid carcinoma

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5
Q

What condition is due to failure of the LES to relax attributed to loss of myenteric (Auerbach’s) plexus?

A

Achalasia

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6
Q

Achalasia is associated with what physiology and symptoms?

A

High LES opening pressure and uncoordinated peristalsis. Progressive dysphagia for SOLIDS AND LIQUIDS

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7
Q

What is pathologic finding is this? What diseases/syndromes are associated with this radiologic finding?

A

ACHALASIA= “Bird’s Beak” Barium swallow shows dilated esophagus with an area of distal stenosis

Associated Diseases:

1) Scleroderma (CREST Syndrome): Esophageal dysmotility involving low pressure proximal to LES.
2) South American Immigrant- Think CHAGAS’ DISEASE
3) Lack or Nitrous Oxide implicated in some cases

Associated with INCREASED risk of Esophageal SQUAMOUS CELL CARCINOMA

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8
Q

TRIAD:

1) Dysphagia secondary to esophageal webs
2) Glossitis
3) Iron Deficiency Anema

A

PLUMMER-VINSON SYNDROME

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9
Q

What are esophageal strictures associated with?

A

Lye ingestion & acid reflux

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10
Q

What is a common cause of PAINLESS upper GI bleeds in pts with liver diease?

A

ESOPHAGEAL VARICES- dilated submucosal veins in lower 1/3 of esophagus secondary to portal HTN

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11
Q

What is the most likely cause of painless hematemesis in a bulemic or alcoholic that vomits frequently?

A

MALLORY-WEISS SYNDROME- Mucosal lacerations at teh GASTROESOPHAGEAL junction due to severe vomiting

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12
Q

What causes PAINFUL hematemesis & is a surgical EMERGENCY?

A

BoerHaave Syndrome: TRANSMUAL esophageal rupture due to violent retching. HIGH risk of mediastinal infection

Common Findings Include:

CXR- Pleural Effusions

Crepitus on auscultation of chest wall

Subcutaneous Emphysema

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13
Q

What type of ulcers are found in esophagitis caused by CMV vs HSV?

A

HSV= punched out ulcers

CMV= LINEAR ulcers

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14
Q

Diarrhea, steatorrhea, weight loss, weakness, vitamin & mineral deficiencies are symptoms associated with what type of syndrome? What are some specific diseases?

A

MALABSORPTION SYNDROMES: These Will Cause Devastating Absorption Problems

Tropical Sprue

Whipple’s Disease

Celiac Disease

Disaccharidase Deficiency

Abetolipoproteinemia

Pancreatic Insufficiency

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15
Q

Causes of Pancreatic Insufficiency (increased neutral fat in stool, malabsorption of fat & fat soluble vitamins ADEK)?

A

Cystic Fibrosis

Obstructing Cancer

Chronic Pancreatitis

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16
Q

How does Abetalipoproteinemia present?

A

EARLY childhood with malabsorption and NEUROLOGIC manifestations

Decreased synthesis of lipoprotein B–> inability to generate CM & decreased secretion of cholesterol & VLDL into bloodstream–> fat accumulation in enterocytes

17
Q

What is Acanthosis Nigricans, Virchow’s Node, Krukenberg’s Tumor, & Sister Mary Josph’s Nodule? What can these findings indicate?

A

STOMACH CANCER

Virchow’s Node= involvement of the left supraclavicular node by metastasis from the stomach–> thoracic duct

Krukenberg’s Tumor= bilateral metastases to the OVARIES. Abundant mucus, signet ring cells

Sister Mary Joseph’s Nodule= Subcutaneous PERIUMBILICAL metastasis