Gastrointestinal Flashcards
What does the enzyme renin do?
Converts angiotensinogen into angiotensin 1
What converts angiotensin I into angiotensin II?
Angiotensin converting enzyme
Which organ releases renin?
Kidneys
What does angiotensin II cause?
Vasoconstriction of blood vessels
Stimulates the secretion of vasopressin/ADH
Stimulates release of adrenaline, noradrenaline and aldosterone from hte adrenal gland
What does aldosterone do?
Affects kidneys:
Sodium retention
Water retention
Potassium excretion. More water= higher vol = higher blood pressure
Name the molecules involved in the renin-angiotensin-aldosterone system.
Angiotensinogen –> Angiotensin I –> Angiotensin II
What converts angiotensinogen to angiotensin I?
Renin
Angiotensin II stimulates of adrenaline and noradrenaline. What is the reason for this?
To cause vasoconstriction of blood vessels to decrease vol and increase BP
Where is aldosterone secreted from?
The adrenal cortex
What is the effect of vasopressin?
Also known as ADH. Causes water retention by increasing the number of aquaporins in the collecting ducts of kidneys so more water is reabsorbed.
What is renin released in result of?
Low blood volume in the collecting ducts in the kidney
Where is angiotensin converting enzyme released from?
Lungs
What structure does angiotensin II act on?
Adrenal gland