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Medicine > Gastroenterology - Pharmacy Teaching (IBD, Nausea, Vomiting) > Flashcards

Gastroenterology - Pharmacy Teaching (IBD, Nausea, Vomiting) Flashcards

1
Q

Ulcerative Colitis vs Crohn’s

A
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2
Q

IBD Scoring: HBI and SCCAI - what are these?

A

Harvey Bradshaw Index for Crohn’s - not used as much

Simple Clinical Colitis Activity Index for Ulcerative Colitis - used a lot

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3
Q

IBD Scoring: HBI and SCCAI - what are these?

A

Harvey Bradshaw Index for Crohn’s - not used as much

Simple Clinical Colitis Activity Index for Ulcerative Colitis - used a lot

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4
Q

IBD Scoring - Truelove and Witts

A
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5
Q

IBD Categorisation

FCPL ranges?

A
  • Flare - Sx = moderate to severe
  • FCPL - 0-50 is normal, 50-250 is ok, 300-599 is concerning, >600 worried
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6
Q

Treatment Targets: IBD

Proctitis? - …

Proctosigmoiditis? - Liquid enema and …

Left Sides Colitis? - … enema and … orally

Whole Colon? - Oral medication

A

Proctitis? - Suppositories

Proctosigmoiditis? - Liquid enema and suppositories

Left Sides Colitis? - Foam enema and medication orally

Whole Colon? - Oral medication

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7
Q

Flare Management pathway - IBD

A
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8
Q

Flare Management pathway - IBD

A
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9
Q

UC Maintenance Management: 5ASA

A
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10
Q

Oral mesalazine (also known as mesalamine) is a 5-aminosalicylic acid compound used in the treatment of mild to moderate … …, with high rates of efficacy in induction and maintenance of remission

A

Oral mesalazine (also known as mesalamine) is a 5-aminosalicylic acid compound used in the treatment of mild to moderate ulcerative colitis, with high rates of efficacy in induction and maintenance of remission

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11
Q

UC Flare Management

  • ​What do we do?
A

DOUBLE mesalazine

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12
Q

Does adherence matter in UC?

A

Yes! helps remission

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13
Q

Steroids; UC and Crohn’s

  • … cure - but provide a good effect
  • Ensure not …
  • … care - often not high enough from GPs
  • Concern if >… courses/year
  • mirror IBD Sx
A
  • Short cure - but provide a good effect
  • Ensure not infective
  • Primary care - often not high enough from GPs
  • Concern if >2 courses/year
  • mirror IBD Sx
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14
Q

Steroids; UC and Crohn’s - Flare up

A
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15
Q
  • Alternative Steroids
  • B or B…
A

Budesonide - PO and Rectal

  • 9mg OM 8/52

Beclamethasone - PO

  • 5mg OD 4/52 - 5mg Alt days 4/52 then stop
  • Non inferior to prednisolone
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16
Q

Define Post Operative Nausea and Vomiting

A

Postoperative nausea and vomiting (PONV) is defined as any nausea, retching, or vomiting occurring during the first 24–48 h after surgery in inpatients.

17
Q

Vomiting - pathway

A
18
Q

Risk Assessment for N+V

What score is used?

A
19
Q

Pharmaceutical Management for N+V

A

Antihistamines

5HT3 Antagonists

Phenothiazines

Butyrophenones

Anticholinergics

Dopamine Receptor …

20
Q

Cycylizine - Antihistamine

A
21
Q

Ondansetron - 5HT3 Antagonists

A
22
Q

Phenothiazine - Prochlorperazine

A

Medicine (14 decks)

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