Gastroenterology Flashcards
When to EGD Barrett’s Patients
- EGD shows Barretts -> next EGD 1 year
- 1 year later repeat EGD no dysplasia (only metaplasia) -> EGD q3yr
- Low Grade dysplasia - EGD 6 months -> still low dysplasia -> q1yr
- Dysplasia->metaplasia -> q3yr
- High Grade Dysplasia -> Endoscopic RF Ablation
H Pylori Testing
- Non Endo - Ab test for dx only, Urea breath/Fecal antigen Dx AND f/u
- Endo - for culture, urease testing - GOLD STANDARD but expensive
Treatment H Pylori
- PAC x 14 days (PPI, Amox, Clarithro
2. MOC x 14 days (Metronidazole, omep, clarithro)
H Pylori Tx failure
- Quad Tx - Tetra, metronidaz, bismuth, PPI
DO NOT REPEAT triple therapy with same abx (high clarithro resistance rates)
Who to test for H pylori
45yo M with abd pain and PUD
Are steroids ulcerogenic
NO but with NSAIDS increase bleeding by 10x
Dysphasia solids AND liquids with CP
Diffuse Esophageal spasm/corkscrew esophagus–>barium swallow–>manometric study (non-perstaltic rxn–>PPI (if no response CCB)
First bite dysphagia (intermittent)
Schatzki ring/esophageal strictures -> Pneumatic dilation
Food Regurg hours after, dyphagia solids and liquids
Barium swallow -> Birdsbeak -> Achalaisa-> EGD r/o secondary acalasia (cancer) -> surgical myotomy
Food impaction several times, EGD concentric rings, h/o allergies
Eosinophillic esophagitis -> PPI then aerosolized steroid (fluticasone/budesonide) then if refractory EGD dilation
Dysphagia with osteoporosis, acrne on tetracycline erythromcin
Pill esophagitis -> EGD
regurigating food from days ago, halotosis
zenker’s diverticulum
HIV with oral thrush
empiric fluconazole/itraconazole -> if no response -> EGD r/o CMV/herpes
Long standing heartburn with progressive dysphagia solids
Peptic stricture
Heartburn not relieved with antacids
trial of PPI -> if doesn’t work EGD -> if EGD no esophagitis -> ambulatory pH monitoring to prove GERD
Heartburn no response to PPI + weight loss
EGD
Can PPI/fundoplication reverse barretts
NO
PUD Tx
H2 blocker, PPI, sucralafte (cover ulcer)
Zollinger Ellison
MC radiographic finding=single duodenal ulcer Pancrease or duodenal tumors 2/3 tumors are malignant 1/4 a/w MEN I Serum fasting gastrin >1000, low pH dx