Gastroenterology Flashcards

1
Q

Causes of acute abdominal pain

A

Non-specific abdominal pain and mesenteric adenitis

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2
Q

Why should you take a urine sample?

A

identify DM and conditions affecting the urinary tract

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3
Q

Symptoms and signs of acute appendicitis

A

Symptoms:

  • anorexia
  • vomiting
  • abdominal pain (initial central and colicky then localising to RIF)

Signs:

  • fever
  • abdominal pain aggravated on movement
  • persistent tenderness with guarding in RIF (McBurney’s point)

NB: with retrocaecal appendix, localised guarding may be absent. With pelvic appendix there may be few abdominal signs

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4
Q

In what age can you see appendicitis in childten

differences in adults vs preschool children

A

any age but uncommon in under 3 y/o

diagnosis is more difficult in preschool children, particularly early on in the disease

perforation may be rapid as omentum is less well developed and fails to surround the appendix, and signs easy to underestimate at this age

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5
Q

how do we diagnose appendicits?

A

repeated observation and clinical review every few hours

raised neutrophil (not always present in FBC)

WBCs/organisms in urine can be seen as appendix adjacent to bladder and ureter

USS supports diagnosis = thickened, non-compressible appendix with increased blood flow. also shows complications liek abscess, perforation or an appendix mass

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6
Q

how do we treat acute appendicitis?

A

appendicectomy in uncomplicated

fluid resus and IV abx in complicated (mass, abscess, perforation)

IV abx, then appendicectomy after several weeks if palpable mass with no signs of generalised peritonitis

mx should be guided by the surgical team

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7
Q

Non-specific acute abdominal pain and mesenteric adenitis definition and characteristics

A

NSAP = abdominal pain which resolved in 24-48 hours

  • less severe pain than appendcitis
  • tenderness in RIF is variable
  • often accompanites URTI with cervical lymphadenopathy
  • constipation is a common cause

Mesenteric adenitis

  • large mesenteric nodes observed
  • appendix normal
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8
Q

Non-specific acute abdominal pain and mesenteric adenitis management

A

resolving/self-limiting

if not = laparascopy and appendicectomy

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9
Q

Diagnosing acute abdominal pain in older children and adolescents

A

exclude medical causes = LL pneumonia, DKA, hepatitis, pyelonephritis

check for strangulated inguinal hernia or torsion of the testis in boys

guarding and rebound tenderness absent or unimpressive

pain from peritonela inflammation may be demonstrated on coughing, walking or jumping

distinguish between acute appendicitis and NSAP = close monitoring, joint management between paediatricians and paediatric surgeons, and repeated evaluation in hospital

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10
Q

Intusssusception

age

complications

A

invagination of proximal bowel into distal segement (ileum passing into caecum through ileocaecal valve)

MOST COMMON cause of intestinal obstruction in infants after neonatal period

3 months to 2 years of age

complications:

  • stretching and constriction of mesentery -> venous obstruction, engorgement and bleeding from bowel mucosa -> fluid loss, bowel perforation, peritonitis -> gut necrosis
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11
Q

Intussusception presentation

A

paroxysmal colicky pain with pallor around mouth

  • draws up legs
  • recovery between painful episodes but child may become increasingly lethargic

may refuse feeds, may vomit (may be bile-stained depending on site of intusussception)

sausage-shaped mass (often palpable on abdomen)

redcurrant jelly stool (blood-stained mucus) = occurs later in illness and may be first seen in a rectal examination

abdominal distension and shock

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12
Q

intussusception diagnosis and mx

recurrence

A

AXR = distended small bowel and absence of gas in distal colon or rectum , sometimes outline of intussusception can be outlined and visaulised

USS to confirm diagnosis = target/doughnut sign

IV fluid resus IMMEDIATELY (as pooling of fluid in gut -> hypovolaemic shock) SHOCK IS AN IMPORTANT COMPLICATION AND REQUIRES URGENT TX

rectal air insufflation/air contrast enema (US guided) by radiologist and under supervision of paed surgeon in case procedure is unsuccessful or bowel perforation occurs = when no peritonitis

IF FAIL/PERITONITIS = operative reduction

recurrence occurs in less than 5% but more frequent after hydrostatic reduction

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13
Q

Meckel diverticulum definition

symptoms

ix and findings

what can it mimic

mx

A

ileal remnant of vitello-intestinal duct (2% of people)

contains ectopic gastric muscosa/pancreatic tissue

most asymptomatic but may present with severe rectal bleeding which may be LIFE THREATENING (not bright nor true melaena)

techentium scan = increased uptake by ectopic gastric mucosa

  • negative scan does not exclude possibility and a laparoscopic exam can be used to make the diagnosis

acute reduction in Hb

can mimic appendicitis when inflamed

mx = surgical resection

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14
Q

Malrotation definition and how it turns to volvulus

A

congenital abnormality of the midgut

  • small intestine mostly right-hand side of abdomen
  • caecum URQ
  • Ladd bands (fibrous) tether caecum to URQ -> intestinal obstruction by compressing duodenum -> poorly tethered gut swings and twists more readily -> volvulus -> ischaemia of small and proximal large intestine
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15
Q

malrotation and volvulus presentation

and ix for a specific presentation

and mx for a specific presentation

A

1) obstruction
2) obstruction with compromised blood supply

First few days of life (also seen later in age) = obstruction with bilious vomiting

  • URGENT UGI CONTRAST STUDY to assess intestinal rotation
  • if signs of vascular compromise present = URGENT LAPARATOMY
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16
Q

volvulus mx

A

surgical = untwist volvulus and duodenum mobilised, bowel placed in non-rotated positon, malrotation not corrected but the mesentery broadened, appendix removed to avoid diagnostic confusion if appendicits down the line

17
Q

Defintion of recurrent abdominal pain

Causes and assessment of the child with recurrent abdominal pain

A

episodes of abdominal pain at least 4 times per month sufficient to interrupt normal activities and lasts for at least 2 months

classically periembulical pain and child otherwise entirely well

18
Q

What are FAPDs, give examples of FAPDs

A

Functional abdominal pain or functional abdominal pain syndrome (FAPD/S) is an uncommon functional gut disorder characterised by chronic or recurrent abdominal pain attributed to the gut but poorly related to gut function.

IBS (most common)

Abdominal migraine

Functional dyspepsia

Functional abdominal pain (not otherwise specified, i.e. do not meet above classification)

19
Q

IBS characteristic set of symptoms

A

peri-umbilical non-specific abdominal pain, related to one or more of:

  • defecation
  • alteration in stool frequency
  • change in appearance of stool (diarrhoea or constipation)
20
Q

Differentiating IBS with functional constipation

A

functional constipation = abdominal pain resolved with constipation tx

IBS = does not resolve after tx -> IBS with constipation

21
Q

IBS pathogenesis

A

disorder of visceral hypersensitivity and neurological hypervigilance in combination with psychosocial stressors

  • early life events = bowel surgery
  • environmental = cow’s milk protein allergic, post enteritis
  • GI = infections, abx
22
Q

Abdominal migraine

A

paroxysms of intensee, acute periumbilical, midline or diffuse abdominal pain lasting at least an hour, interfering with normal activities

additional sx = nausea, vomiting, anorexia, headaches, photphobia pallor

inbetween episodes (long periods, often weeks) = of no sx interspersed with episodes following a characteristic pattern for the child

personal/FHx of migraine

similar triggers to classic migraine

similar relieving factors

can evolve into migraine headaches in adult life

23
Q

Functional dyspepsia

A

postprandial fullness/early satiety

w/wo upper abdominal bloating, nausea or excessive belching, or severe pain or burning in epigastric area

pain not relieved by defecation

induced/relieved by eating

24
Q

Mx of FAPDs

A

Bio

  • low FODMAP diet
  • anti-spasmodics and alternative therapies
  • anti-migraine (for abdominal migraine)
  • acid blockade w/ histamine receptor antagonists and PPI (functional dyspepsia)

Psychosocial

  • pain is real not imaginary
  • ‘sometimes insides of intestine become so sensitive that some children can feel the foods going round the bends’
  • serious (loss of schooling) vs dangerous
  • avoid triggers and psychosocial factors
  • behaviour modification (improve coping mechanisms and avoid reinforcement of pain) e.g. relaxation, distraction and hypnotherapy where hypnotherapy is most effective
25
Q

LT prognosis of FADPs

A

1/2 of affected children rapidly become free of sx

1/4, sx take months to resolve

1/4, sx continue or return in adulthoods as IBS, migraine or functional dyspepsia

26
Q

PUD

A

uncommon in children

epigastric pain

  • wakes them up at night
  • radiates to back
  • Hx of PUD in 1o relative

H. Pylori infection

Ix:

  • gastric biospy on endoscopy
  • 13C breath test or stool antigen test to confirm successful eradication of H. pylori infection
  • non-invasive tests NOT recommended in children for initial diagnosis and tx

Mx:

  • PPI
  • eradication therapy with abx if H. pylori identified
27
Q
A