Gastroenterology Flashcards

1
Q

Barium swallow, EGD, mamometry: Which test do we do first if suspect achalasia?

A

Barium swallow

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2
Q

When do you do an ambulatory esophageal pH monitoring for GERD?

A

After a normal upper endoscopy and have sx refractory to PPIs

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3
Q

Before having antireflux surgery for GERD, what 2 tests should a patient undergo?

A

pH monitoring and manometry

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4
Q

What is the titration of PPI before doing an upper endoscopy for GERD?

A

daily PPI then BID for 4-8 weeks

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5
Q

Who should be screened for Barrett esphagus?

A

men >50 yo with GERD for more than 5 years with additional risk factors like nocturnal reflux sx, hiatal hernia, elevated BMI, tobacco use and intraabdominal distribution of fat

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6
Q

What is the treatment for Barrett esphagus without dysplasia?

With low or high grade dysplasia?

A

PPI

ablation

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7
Q

How frequently do you do surveillance exams for Barrett esophagus without dysplasia? with low grade dysplasia?

A

Without: 3-5 years

Low grade dysplasia: 6-12 months who don’t choose endoscopic ablation

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8
Q

what are the 3 most common infections causing esophagitis?

A

candida albicans, CMV and HSV

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9
Q

What 5 medications cause pill-induced esophagitis?

A

tetracyclines, NSAIDs, potassium chloride, iron, alendronate

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10
Q

what can be seen on upper endoscopy as mucosal furrowing, stacked circular rings, white specks and mucosal friability?

A

eosinophilic esophagitis

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11
Q

What is a mimicker of eosphageal eosinophilia? How can you tell the difference?

A

GERD

8 week trial of PPI, if improvement, then it is GERD associated instead of eiosinophilic

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12
Q

What are the top 2 causes of peptic ulcer disease?

A

H pylori and NSAIDs

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13
Q

What are 4 complications of peptic ulcer disease?

A

penetration, perforation, outlet obstruction, bleeding

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14
Q

How should a patient <60 yo with dyspepsia without alarm symptoms, be tested for H pylori?

A

Do a “test and treat” approach including urea breath test and stool test

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15
Q

How should a patient >60 yo or those with alarm sx be tested for H pylori?

A

upper endoscopy and H pylori testing

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16
Q

T/F: antibiotics, busmuth containing compounds or PPIs can give you a false negative H pylori test

A

T

Wait 28 days for abx, 2 weeks for PPIs

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17
Q

What can be used to treat H pylori if there is clarithromycin resistance?

A

bismuth quadruple therapy

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18
Q

When is follow up upper endoscopy for gastric ulcers performed?

A

if symptomatic after treatment, cause is uncertain or biopsies not performed initially

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19
Q

T/F: Duodenal PUD without complications requires a follow up upper endoscopy

A

F

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20
Q

What therapy should be used in H pylori with patients with a penicillin allergy?

A

Bismuth quadruple therapy

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21
Q

what 4 meds can cause dyspepsia?

A

NSAIDs, abx, bisphosphonates, potassium supplements

22
Q

What should be investigated for if have acute gastroparesis?

A

pyloric channel obstruction with upper endoscopy

23
Q

What is the next step if patient with gastroparesis with chronic symptoms or negative findings on upper endoscopy?

A

nuclear medicine solid-phase gastric emptying study

24
Q

T/F: A low blood glucose can impair gastric emptying

A

F; hyperglycemia over 275 can cause gastric emptying

25
What medication can be used for acute vs chronic gastroparesis?
acute: IV erythromycin chronic: metaclopramide
26
What are 2 serious side effects of metaclopramide?
tardic dyskinesia and dystonia
27
What causes loose stools and malabsorption following bypass surgery?
blind loop syndrome (SIBO) | tx: abx and nutritional supplements
28
What causes abdominal pain, bloating, difficulty belching after fundoplication?
gas-bloat syndrome | tx: diet modification
29
What 8 medications can cause pancreatitis?
sulfonamides, estrogens, didanosine, valproic acid, thiazide diuretics, azathioprine/6MP, pentamidine, furosemide
30
What 4 diseases can cause increased amylase besides pancreatitis?
kidney disease, intestinal ischemia, appendicitis, parotitis
31
What is the treatment for pancreatic pseudocytsts?
usually resolve spontaneously if sx, then can do transgastric or transduodenal drainage
32
What is the most common cause of chronic pancreatitis?
chronic alcohol use
33
What is the next step after calcifications in the pancreas is NOT seen on CT for a patient with suspected chronic pancreatitis?
MRI, MRCP or endoscopic US
34
What dx can present with "sausage-shaped" pancreatic enlargement with an indistinct border on cross sectional imaging?
autoimmune pancreatitis
35
Which type of autoimmune pancreatiits can be seen in older men, pancreatitis, Sjogren syndrome, PSC, bild duct strictures, autoimmune thyroiditis and interstitial nephritis? What lab value is elevated?
type I | IgG4 increased
36
Which type of autoimmune pancreatiitis is associated with chronic pancreatitis and IBD?
type II
37
What is the treatment for autoimmune pancreatitis?
glucocorticoids
38
Which bacteria can mimic appendicitis or Crohn disease?
Yersinia enterocolitica colitis
39
Which diarrheal illness is common in AIDS?
cryptosporidiosis
40
What is the treatment for diarrhea caused by giardia lamblia or entamoeba histolytica?
flagyl
41
What is the consequence of using loperamide or diphenoxylate for acute diarrhea with EHEC colitis and C diff?
EHEC--causes HUS | C diff--causes toxic megacolon
42
What is the most common infectious cause of chronic diarrhea in developed world in immunocompetent patient?
giardia lamblia
43
What is the first step in evaluation of chronic diarrhea?
colonoscopy eval for Crohn disease and microscopic colitis
44
What is the next step if colonoscopy is negative in evaluating chronic diarrhea?
48-72 hour stool collection with analysis of fat content fat excretion >14g/d is diagnostic of steatorrhea
45
What is the differential for steatorrhea? (3)
small bowel malabsorption disorders, bacterial overgrowth, pancreatic insufficiency
46
What is the formula to calculate osmotic gap?
290- (2x(Na+K)) omostic gap of >100=osmotic diarrhea gap of <50 is secretory diarrhea measured stool osm <250 means factitious diarrhea
47
What is the most common cause of osmotic diarrhea?
lactase deficiency associated with eating, improves with fasting, not nocturnal
48
What sets osmotic and secretory diarrhea apart?
secretory=unchanged by fasting, osm gap<50, nocturnal
49
What is diagnosed in diarrhea in women 45-60yo unreleated to food intake with normal colonoscopy?
microscopic colitis, stop NSADs/PPI, biopsy
50
What is diagnosed with coexistent pulm disease and/or recurrent Giardia infection? (2)
CVI and selective IgA deficiency
51
Malabsorption
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