Gastro-Intestinal Tract Flashcards

1
Q

what are the mouth, esophagus, pharynx, stomach, small intestine and large intestine collectively known as?

A

alimentary canal

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2
Q

what are the 4 major tissue layers that make the GIT tract?

A
  1. mucosa
  2. submucosa
  3. muscularis externa
  4. serosa
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3
Q

what are the 4 main functions of the GIT?

A
  1. motility
  2. secretion
  3. digestion
  4. absorption
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4
Q

what are the 2 types of digestive motility?

A
  1. propulsive movement

2. mixing movement

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5
Q

where does most absorption occur in the GIT?

A

small intestine

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6
Q

what are the 2 nervous systems that regulate the functioning of the GIT?

A

Intrinsic [Enteric Nervous System], Extrinsic [ Autonomic Nervous System]

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7
Q

what are the 2 plexuses of the enteric nervous system?

A
  1. Myenteric plexus [Auerbach]

2. Submucosal plexus [plexus of Meissner]

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8
Q

what is the difference in function of the parasympathetic and sympathetic nervous systems in the GIT?

A
PNS= stimulates motility and secretion via Vagus nerve
SNS= inhibits digestion
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9
Q

what is the term synonymous to Swallowing?

A

deglutition

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10
Q

what are the 3 phases of swallowing and is each phase voluntary or involuntary?

A
  1. Buccal [oral] phase= voluntary
  2. Pharyngeal phase= involuntary
  3. Esophageal phase= involuntary
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11
Q

what are the 2 sphincters present in the esophagus?

A

pharyngoesophageal sphincter and gastroesophageal sphincter

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12
Q

what are the 3 developments within the stomach that prevent it from digesting itself?

A
  1. epithelial cells with tight junctions
  2. thick coat of bicarbonate-rich mucus on wall
  3. gastric glands that are impermeable to HCl
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13
Q

what are the 4 types of gastric exocrine secretory cells and their functions?

A
  1. Parietal cells = secrete HCl and intrinsic factor
  2. G cells= secrete hormones and other substances
  3. Chief Cells= pepsinogen
  4. Mucous Cells= mucus
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14
Q

what are the 3 phases of the regulation of gastric juice secretion?

A
  1. cephalic phase
  2. gastric phase
  3. intestinal phase
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15
Q

what are the 3 ligands that stimulate HCl secretion?

A

ACh, Histamine, Gastrin

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16
Q

what happens at the antrum of the stomach?

A

mixing occurs

17
Q

what feature of the stomach closes to prevent food from leaving the stomach while mixing occurs.

A

pyloric sphincter

18
Q

what are the 3 segments of the small intestine?

A

duodenum, jejunum, ileum

19
Q

true or false. The juice secreted by the small intestine cells contains digestive enzymes

20
Q

what stimulates the defecation reflex?

A

stretch receptors in rectal wall are stimulated by distension.

21
Q

which hormone is released due to the presence of proteins in the stomach?

22
Q

which hormone is released due to the presence of acid in the duodenum?

23
Q

give two functions of the hormone secretin

A
  1. inhibits gastric emptying
  2. stimulates liver to release Na2CO3 for neutralization
  3. inhibits gastric acid release
24
Q

which hormone stimulates pancreatic acinar cells to secrete pancreatic enzymes?

A

Cholecystokinin

25
what is the importance of the liver in the digestive system?
secretes bile salts
26
what does the hepatic portal vein do?
carries deoxygenated nutrient rich blood from the GIT to the liver for processing.
27
when and where are bile salts released from the gallbladder and why?
bile salts are released after meals into the duodenum into to break down large fat globules into smaller droplets.
28
true or false. digestion of carbohydrates occurs in the stomach.
false
29
what are chylomicrons?
lipoproteins composed mainly of triglycerides that transport cholesterol, phospholipids and proteins from dietary lipids from intestines via lymphatic system to other parts of the body.
30
name the fat soluble vitamins
A,D,E,K
31
what is the major cause of ulcer formation?
Helicobacter pylori bacteria
32
what causes gallstones?
when the concentration of cholesterol in the bile is greater than the concentration of the phospholipids and bile salt, , the cholesterol crystalizes
33
what is the condition characterized by large, frequent watery stools termed as
diarrhea
34
what causes lactose intolerance?
when lactase does does not properly digest lactose