Gastro-Intestinal Tract Flashcards
what are the mouth, esophagus, pharynx, stomach, small intestine and large intestine collectively known as?
alimentary canal
what are the 4 major tissue layers that make the GIT tract?
- mucosa
- submucosa
- muscularis externa
- serosa
what are the 4 main functions of the GIT?
- motility
- secretion
- digestion
- absorption
what are the 2 types of digestive motility?
- propulsive movement
2. mixing movement
where does most absorption occur in the GIT?
small intestine
what are the 2 nervous systems that regulate the functioning of the GIT?
Intrinsic [Enteric Nervous System], Extrinsic [ Autonomic Nervous System]
what are the 2 plexuses of the enteric nervous system?
- Myenteric plexus [Auerbach]
2. Submucosal plexus [plexus of Meissner]
what is the difference in function of the parasympathetic and sympathetic nervous systems in the GIT?
PNS= stimulates motility and secretion via Vagus nerve SNS= inhibits digestion
what is the term synonymous to Swallowing?
deglutition
what are the 3 phases of swallowing and is each phase voluntary or involuntary?
- Buccal [oral] phase= voluntary
- Pharyngeal phase= involuntary
- Esophageal phase= involuntary
what are the 2 sphincters present in the esophagus?
pharyngoesophageal sphincter and gastroesophageal sphincter
what are the 3 developments within the stomach that prevent it from digesting itself?
- epithelial cells with tight junctions
- thick coat of bicarbonate-rich mucus on wall
- gastric glands that are impermeable to HCl
what are the 4 types of gastric exocrine secretory cells and their functions?
- Parietal cells = secrete HCl and intrinsic factor
- G cells= secrete hormones and other substances
- Chief Cells= pepsinogen
- Mucous Cells= mucus
what are the 3 phases of the regulation of gastric juice secretion?
- cephalic phase
- gastric phase
- intestinal phase
what are the 3 ligands that stimulate HCl secretion?
ACh, Histamine, Gastrin
what happens at the antrum of the stomach?
mixing occurs
what feature of the stomach closes to prevent food from leaving the stomach while mixing occurs.
pyloric sphincter
what are the 3 segments of the small intestine?
duodenum, jejunum, ileum
true or false. The juice secreted by the small intestine cells contains digestive enzymes
false
what stimulates the defecation reflex?
stretch receptors in rectal wall are stimulated by distension.
which hormone is released due to the presence of proteins in the stomach?
gastrin
which hormone is released due to the presence of acid in the duodenum?
secretin
give two functions of the hormone secretin
- inhibits gastric emptying
- stimulates liver to release Na2CO3 for neutralization
- inhibits gastric acid release
which hormone stimulates pancreatic acinar cells to secrete pancreatic enzymes?
Cholecystokinin