gastro Flashcards
When to screen Barrett esophagus
No dysplasia -> 1 year, then every 3 years.
Low-grade -> every 6 months.
High-grade -> ablation
Treatment for H. pylori
Clarithromycin, amoxicillin (or metronidazole), and PPI for 10-14 days
Thiamine deficiency signs
Nystagmus, ophthalmoplegia, ataxia, and confusion
Study to predict severity of pancreatitis
BUN
stool osmotic gap
290 - 2 x [stool Na - tool K] ->
100 is osmotic
Celiac disease serologic test
tissue transglutaminase IgA
Sign of ulcerative colitis
acute onset, start at rectum, continuous mucosal microulcerations
Sign of Crohn disease
gradual onset, transmural disease with skip lesions
Dermatologic signs of IBS
erythema nodosum and pyoderma gangrenosum
Who gets acute mesenteric ischemia
older than 50 with cardiac disease
Presentation of acute mesenteric ischemia
acute onset of acute pain, soft abdomen, pain out of proportion to exam
Hereditary Nonpolyposis Colorectal Cancer
colorectal adenomas develop by age 20-30
Familial Adenomatous Polyposis
hundreds of colorectal adenomas by age 16
Peutz-Jeghers Syndrome
mucocutaneous melanocytic macules and gastrointestinal hamartomatous polyps
Polyp, low risk screening
1-2 adenomas, repeat in 5-10 yrs
Polyp, high risk screening
> 2 adenomas, >1cm, villous, high grade dysplasia -> repeat in 3 yrs
Extrahepatic manifestations of hepatitis B
polyarteritis nodosum and membranous glomerulonephritis
Extrahepatic manifestations of hepatitis C
mixed cryoglobulinemia, membranoproliferative glomerulonephritis, porphyria cutanea tarda, and non-Hodgkin lymphoma
Signs of primary biliary cirrhosis
50 yo women with fatigue, dry eyes and mouth, and pruritis
Blood tests for primary biliary cirrhosis
elevated alkaline phosphatase, ast, alt, normal bilirubin. often antimitochondrial antibodies
Histology for primary biliary cirrhosis
focal duct obliteration with granuloma formation
Signs of primary sclerosing cholangitis
40 yo, with pruritis, abdominal pain and jaundice. many with inflammatory bowel disease
Blood tests for primary sclerosing cholangitis
elevated alkaline phosphatase, ast, alt.
Imaging for primary sclerosing cholangitis
cholangiography shows segmental bile duct fibrosis with saccular dilatation resulting in “beads on a string”