Gastritis

Question 1

What is gastritis?

Answer 1

It is the inflammation of the stomach

Question 2

What are common complications of gastritis?

Answer 2

• Bleeding
• Ulceration
• Cancer

Question 3

What are common causes of gastritis?

Answer 3

• Stress
• Spicy foods, coffee
• Alcohol
• Cocaine
• NSAIDs
• H. pylori
• Cocaine

Question 4

What are the acute causes?

Answer 4

• alcohol
• aspirin
• NSAIDs
• Stress
• H. pylori

Question 5

What are the causes of chronic gastritis?

Answer 5

Atrophic - H. pylori, dietry
Chemical - Bile, NSAIDs
Radiation - radiation 
Lymphocytic - Coeliacs
Infectious - Viruses, bacteria, TB, syphilis, parasite

Question 6

What is the pathophysiology of NSAIDs causing acute gastritis?

Answer 6

1. NSAIDs inhibit cyclo-oxygenase-1
2. COX-1 is an enzyme responsible for the synthesis of eicosanoids in the stomach
3. With less eicosanoids this increases the chance of peptic ulcers
4. With less prostaglandins can lead to gastritis

Question 7

how does alcohol cause gastritis?

Answer 7

Erodes the lining and small amounts stimulates the secretion of HCL.

Question 8

What is metaplasia?

Answer 8

Is the reversible transformation from once cell type to another cell type.

Question 9

What is used in the process of diagnosis?

Answer 9

Blood tests 
- FBC
Stool sample - H. pylori, blood
Biopsy 
Endoscopy

Question 10

What is the treatment

Answer 10

1. Treat based on cause
2. Mild - antacids
3. Moderate and severe 0 PPI and H2 blockers