Gastric Motility - Prunuske

Question 1

Is vagal release of ACh during accommodation associated with contraction or relaxation of the stomach?

Answer 1

Relaxation

Question 2

What are the Gastroileal and Gastrocolic reflexes?

Answer 2

Gastroileal reflex- causes ileoceccal valve to relax transfer contents from small to large bowel
Gastrocolic reflex- induces the need to defecate after ingesting a meal

Question 3

(T/F) Lipid soluble substance such as alcohol and aspirin can be absorbed by diffusion but there is no active transport

Answer 3

True. Lipid soluble substance such as alcohol and aspirin can be absorbed by diffusion but there is no active transport

Absorption of these substances is associated with gastritis.

Question 4

Migrating Motor Complex- housekeeping function to remove indigestible material during [ ] induced by motilin.

Answer 4

Migrating Motor Complex- housekeeping function to remove indigestible material during FASTING induced by motilin.

Question 5

Congenital condition where pylorus fails to relax after a meal leading to malnutrition and dehydration. How do you treat?

Answer 5

Pyloric Stenosis. Treated with surgical myotomy.

Question 6

Reduced gastric emptying often due to diabetic neuropathy involving the vagus and enteric nerves in the stomach such that the stomach fails to generate enough force to empty the stomach. Other causes include drugs and cancer treatments. Results in nausea, vomiting, bloating, poor digestion, weight loss, malnutrition, impaired absorption of medications, and impaired glycemic control. How do you treat?

Answer 6

Gastroparesis. Treat with prokinetic drugs.

Question 7

Rapid gastric emptying often resulting from gastric bypass surgery, vagotomy, and high sugar-containing meals. Rapid entry of gastric contents into the duodenum represents an osmotic challenge, water moves into the lumen resulting in hypovolemia and reduced blood pressure. Results in nausea, weakness, dizziness, sweating, shakiness, diarrhea, heart palpitations

Answer 7

Dumping Syndrome

Question 8

Scarring and ulcers near the pylorus can delay emptying or in duodenal ulcers can lead to rapid gastric emptying due to loss of duodenal negative feedback mechanisms.

Answer 8

Peptic ulcer disease.

Question 9

Causes of vomiting?

Answer 9

Causes: gastritis, poisoning, brain tumors, increased intracranial pressure, migraine, vestibular problems, bowel obstruction, appendicitis.

Emetic stimulants include stimulation of the pharynx, sensory input from higher centers, vestibular information, irritants or blockage in the GI tract, and blood-borne emetics.