Gastric Carcinoma Flashcards
How does gastric carcinoma present?
weight loss and abdominal pain, although patients with proximal or gastro-oesophageal junction tumours may present with dysphagia
How is it diagnosed?
Upper gastrointestinal endoscopy with biopsy demonstrating carcinoma is required to confirm the diagnosis. Staging based on imaging is required.
How is it treated?
Early-stage disease is treated with surgery alone.
Locally advanced disease is treated with multimodality approach that includes surgery followed by postoperative chemoradiation, or chemotherapy before and after surgery.
Metastatic disease is treated with chemotherapy, immunotherapy, or chemoradiation and supportive care measures.
What are complications of gastric carcinoma
Common complications are gastric bleeding and gastric outlet obstruction.
What are most tumour types?
Adenocarcinoma
What are some upper GI RF?
- pernicious anaemia
- Helicobacter pylori
- N-nitroso compounds
- diet low in fruits and vegetables
